Cases reported "Abnormalities, Multiple"

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1/4. Gerstmann tetrad in leopard syndrome.

    We report a 12-year-old boy with multiple lentigines (Leopard) syndrome who was evaluated for learning difficulties and Gerstmann tetrad syndrome (i.e., dyscalculia, left-right disorientation, finger agnosia, and dysgraphia). Cranial computed tomography revealed left ventriculomegaly, more pronounced in the occipital horn suggesting mild atrophy of the left parietal lobe. This is the first report of an association between the Leopard and Gerstmann syndromes and one of the few to demonstrate a computed tomographic abnormality in the latter.
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keywords = leopard syndrome, leopard
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2/4. The occurrence of supernumerary teeth with isolated, nonfamilial leopard (multiple lentigines) syndrome: report of case.

    A case of leopard syndrome with abnormal dental findings of supernumerary teeth is described. The risks involved with providing dental care to patients with this syndrome is also discussed.
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ranking = 0.39606412373755
keywords = leopard syndrome, leopard
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3/4. 'Leopard spot' retinopathy in Warburg syndrome.

    A female infant with brain and muscle abnormalities characteristic of Warburg syndrome had an atypical retinal dysplasia which appeared clinically as a 'leopard spot' retinopathy. The retinal histology is described in detail and is remarkable for periodic thinning of the inner nuclear layers and for isolated rosettes in the periphery. We believe 'leopard spot' retinopathy is yet another ocular manifestation of the Warburg syndrome.
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ranking = 0.073032061868774
keywords = leopard
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4/4. Factitial dermatitis as the presenting sign of multiple lentigines syndrome. Therapeutic effect of autodermabrasion.

    Factitial dermatitis was the presenting sign of the multiple lentigines syndrome (leopard syndrome) in a young woman. Six years of an unremitting succession of erosive lesions was medically interpreted as a continuous, nonverbal appeal for help in avoiding an undesirable job. Manifestations of her multiple lentigines syndrome included generalized lentigines, mild mental retardation, diabetes mellitus, transitory ECG abnormalities, a cardiac murmur, ocular hypertension, eye muscle paresis, webbed toes, and skeletal deformities of the hands and chest. Through the years, the repetitive sequence of factitial, erosive, nonscarring lesions eradicated her lentigines, leaving the relatively inaccessible back as the only site of residual multiple lentigines.
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ranking = 0.25
keywords = leopard syndrome, leopard
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