1/7. sex-determining region Y levels in maternal plasma: Evaluation in abnormal pregnancy.AIM: A number of studies for the measurement of cell-free fetal dna in maternal blood have been reported; however, their clinical significance has remained unclear. We proposed to clarify the relationship between fetal dna levels and obstetrical disorders. methods: One hundred and eighty-five cases of normal pregnancy, ranging from 8 to 40 weeks' gestation, and 70 cases of abnormal pregnancy were included. SRY levels in maternal plasma were quantified with a real-time quantitative polymerase chain reaction. RESULTS: sex-determining region Y (SRY) levels and the number of patients with positive levels peaked at 33-36 weeks in normal pregnancy. The SRY levels in threatened abortion (11.6 /- 4.8 copies/mL to 0 /- 0, P < 0.05) and threatened preterm labor (44.6 /- 16.1 copies/mL to 15.9 /- 6.2, P < 0.01) were significantly higher than those of the normal group. In pre-eclamptic patients, SRY levels were markedly higher than those of the normal group (173.2 /- 94.8 copies/mL to 22.4 /- 8.9, P < 0.05). patients with premature separation of the placenta (266.8 /- 137.1 copies/mL to 4.9 /- 3.7, P < 0.05) and placenta previa (167.7 /- 32.4 copies/mL to 37.0 /- 17.3, p <0.01) also showed elevated SRY levels. CONCLUSION: sex-determining region Y levels in maternal plasma were elevated in patients with an abnormal pregnancy, particularly those with placental injury of damage. These results suggested that increased SRY levels are consistently caused by the leak of fetal components, and thus the measurement of SRY levels in maternal plasma is useful for the evaluation of placental injuries.- - - - - - - - - - ranking = 1keywords = abortion (Clic here for more details about this article) |
2/7. Transient parkinsonism: induced by progesterone or pregnancy?We report on the development of transient parkinsonism after progesterone injection in a pregnant patient with a risk of abortion. Etiological possibilities are discussed, including pregnancy itself, possible toxic effects of the dead fetus, and progesterone injection. progesterone-induced parkinsonism seems the most likely diagnosis in this case.- - - - - - - - - - ranking = 1keywords = abortion (Clic here for more details about this article) |
3/7. Treating threatened abortion with Chinese herbs: a case report.In the report a patient who suffered from threatened abortion was successfully cured with Chinese herbs. After treatment, vaginal bleeding stopped and the aching sensation in the loins and prolapsing sensation in the abdomen disappeared. The gestational ring changed from a crescent moon shape to a normal shape.- - - - - - - - - - ranking = 5keywords = abortion (Clic here for more details about this article) |
4/7. A case of rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis?Despite the recommended 28 weeks' gestation antenatal, postnatal, and postabortion prophylaxis with Rh immune globulin, residual Rh immunization still occurs in Rh-negative women. We describe a patient whose history suggests development of an anti-D antibody after first-trimester bleeding. To our knowledge, this is the first such case reported in the English literature.- - - - - - - - - - ranking = 5keywords = abortion (Clic here for more details about this article) |
5/7. Velamentous insertion of the umbilical cord and vasa previa.We report 31 cases with velamentous insertion of the umbilical cord of whom two had coexistent vasa previa. The prevalence of the former was 0.22% and of the latter 0.014%. perinatal mortality was low, 3.2%, but there was a high rate of complications during pregnancy, such as threatened abortion, antepartum and intrapartum bleeding, premature delivery and fetal distress. Fifteen patients underwent caesarean section. Four of the term infants were small for gestational age. One infant had congenital malformations. The two cases with vasa previa are described in detail. We conclude that velamentous insertion of the umbilical cord should be kept in mind in the differential diagnosis of fetal distress accompanied with antepartum or intrapartum vaginal bleeding.- - - - - - - - - - ranking = 1keywords = abortion (Clic here for more details about this article) |
6/7. Prevention of fetal growth retardation by buffy-coat transfusions--a case report.A case is described with two previous unsuccessful pregnancies (one missed abortion and one severe fetal intrauterine growth retardation ending in fetal death). Examination showed that the patient and her husband each share one antigen of the HLA-A and -B series. In spite of two previous pregnancies the patient had no lymphocytotoxic antibodies. The patient then received 5 buffy-coat-pool transfusions and the sera reacted with an increasing number of panel cells (Fig. 1). A mature healthy infant was born at term. We consider that the cytotoxic antibodies achieved, took over a protective function for the later undisturbed progress of the pregnancy. This may be a possible way of preventing intrauterine growth retardation caused by immunologic factors.- - - - - - - - - - ranking = 1keywords = abortion (Clic here for more details about this article) |
7/7. Gonococcal endocarditis after a threatened abortion. A case report.BACKGROUND: Disseminated gonocococcal infection arising during pregnancy is an uncommon occurrence. Gonococcemia following a threatened abortion has not been documented previously. CASE: Gonococcal arthritis and endocarditis in a 22-year-old primigravida occurred following a midtrimester threatened abortion. CONCLUSION: Since gonococcemia is thought to be secondary to endocervical disruption, chemoprophylaxis in the gravid cardiac patient after a threatened abortion is recommended.- - - - - - - - - - ranking = 7keywords = abortion (Clic here for more details about this article) |