1/10. Transient acanthosis-nigricans-like dermatosis in re-epithelializing lesions of pemphigus foliaceus.A patient is described who developed hyperkeratotic, hyperpigmented plaques, similar to acanthosis nigricans in re-epithelializing erosions of pemphigus foliaceus. The lesions regressed completely after a few months. This phenomenon can be attributed to a Kobner phenomenon after epidermal damage or can be a result of systemic corticosteroid therapy.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
2/10. Malignant acanthosis nigricans, tripe palms and the sign of Leser-Tre'lat, a hint to the diagnosis of early stage ovarian cancer: a case report and review of the literature.BACKGROUND: Malignant acanthosis nigricans is a mucocutaneous eruption associated with internal malignancies. Tripe palms refers to a characteristic velvety thickening of the palms, with exaggeration of normal skin markings. The sign of Leser-Tre'lat is the presence of multiple seborrheic keratoses and scattered skin tags caused by a malignancy. We are reporting the first case of ovarian cancer in association with three coexisting cutaneous paraneoplastic dermatosis. CASE: A 52-year-old female presented with skin manifestation consistent with MAN, TP and the sign of Leser-Tre'lat. Patient underwent extensive work up and was discovered to have stage I, high grade adenocarcinoma of the ovary. skin manifestations gradually recovered after initiation of chemotherapy. CONCLUSION: The presence of acanthosis nigricans in conjunction with tripe palms and the sign of Leser-Tre'lat are highly suggestive of an internal malignancy and necessitate an extensive investigation in order to discover the underlying malignancy.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
3/10. Malignant acanthosis nigricans and its unusual association with carcinoma of the colon and carcinoma of the cervix.Malignant acanthosis nigricans is rarely associated with carcinoma of the bowel or cervix. However, this dermatosis is described in a case of adenocarcinoma of the ascending colon, and in another with carcinoma of the cervix.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
4/10. Steroid-induced acanthosis nigricans in dermatomyositis.acanthosis nigricans of the groin, axillae, and neck developed in a patient on long-term steroid therapy for dermatomyositis after eight years. The dermatosis resolved spontaneously ten years after the steroid use had been discontinued. review of three personal cases and the literature suggests that acanthosis nigricans may have a hormonal basis.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
5/10. acanthosis nigricans maligna. Clinical and virological investigations.2 cases of acanthosis nigricans associated with an adenocarcinoma (signet ring cell carcinoma) of the stomach and a metastasizing small-cell carcinoma of unknown origin are reported. In both cases the skin lesions preceded the diagnosis of the carcinoma by months and acanthosis nigricans maligna was suspected by onset and localization of the dermatosis. There was no evidence of a papillomavirus etiology of the warty skin lesions. Virus particles could not be demonstrated either in ultrathin sections or in buffer extracts. Virus-specific dna was not detectable after CsCL-ethidium bromide gradient centrifugation and cellular dna did not hybridize under stringent or relaxed conditions with 32P-labelled human papillomavirus 6 or human papillomavirus 8 dna.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
6/10. Cutaneous manifestation of internal malignancies (I). acanthosis nigricans.Skin changes may be the first clue to a neoplastic process at a stage when it still is treatable (Such as the development of Acanthosis Nigrican (AN) in an otherwise healthy adult). Ninety percent of the neoplasm responsible for the development of AN originate in the abdomen. The tumor, even in a subclinical state, seems to possess unidentified properties that activate the dermatosis.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
7/10. Reticulate pigmented anomaly of the flexures. Dowing Degos disease, a new genodermatosis.Acquired reticulate pigmentation of the flexures developed in ten patients. Additional features in some cases were pitted scars near the angles of the mouth and scattered dark comedone-like lesions on the neck (dark dot follicles). The disease affects both sexes, usually develops in early adult life, and is slowly progressive. The abnormality is characterized by pigmented filiform epidermal downgrowths closely resembling an adenoid seborrheic wart, but similar proliferations also develop around the variably dilated pilosebaceous follicles. The occurence of the anomaly in siblings and in mother and daughter in two families suggests the condition in a new genodermatosis. Reticulate pigmented anomaly of the flexures bears a spurious clinical resemblance to acanthosis nigricans and, thus, the recognition of this new genodermatosis should spare patients undergoing unnecessary investigations to exclude visceral malignancy.- - - - - - - - - - ranking = 1.5keywords = dermatosis (Clic here for more details about this article) |
8/10. Reticulate pigmented anomaly of the flexures. case reports and genetic investigation.Reticulate pigmented anomaly of the flexures is a pigmented macular disease characterized by punctate, hyperpigmented macules on the flexural areas. Histopathologic findings include acanthosis, keratinization of the follicular infundibulum, and filiform downgrowths of epidermal cells. Examination of a family has revealed the presence of the disease in six members. Analysis of these data suggests that reticulate pigmented anomaly of the flexures is an autosomal dominant genodermatosis with possibly variable penetrance, variable expressivity, and delayed onset.- - - - - - - - - - ranking = 0.25keywords = dermatosis (Clic here for more details about this article) |
9/10. Pseudoatrophoderma colli. A familial case.A case of familial pseudoatrophoderma colli was found in a 22-year-old Indian woman whose sister and father had similar eruptions. Pseudoatrophoderma colli is an unusual papillary dermatosis in which the lesions appear atrophic. The condition responded very well to treatment with 5% lactic acid ointment. It is likely that pseudoatrophoderma colli is more common than has been reported. It should be considered in the differential diagnosis, along with acanthosis nigricans and confluent and reticulated papillomatosis of Gougerot and Carteaud when a pigmented and papillary dermatosis is present around the neck and upper part of the thorax.- - - - - - - - - - ranking = 0.5keywords = dermatosis (Clic here for more details about this article) |
10/10. Terra firma-forme dermatosis.Terra firma-forme dermatosis (TFFD) is a relatively common but usually unrecognized clinical problem. The cause is unknown. The changes usually occur on the neck in childhood as dirty brown patches that cannot be removed with soap but are easily removed with alcohol. Terra firma-forme dermatosis may be mistaken for acanthosis nigricans.- - - - - - - - - - ranking = 1.5keywords = dermatosis (Clic here for more details about this article) |
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