1/10. Acrokeratosis paraneoplastica (Bazex syndrome) with adenocarcinoma of the colon: report of a case and review of the literature.Acrokeratosis paraneoplastica is a rare disease and is uncommon even in patients with upper aerodigestive tract cancer. We report a 63-year-old man with a 1-month history of numerous pruritic lesions and vesicles on both feet. Although he had received local therapy, progressive dense scale formation involving both palms and both soles was found. colonoscopy was performed because of hematochezia, and it revealed an early colon cancer. After the resection of the cancer, the skin lesions began to fall off dramatically. To the best of our knowledge, there is no report of acrokeratosis paraneoplastica associated with colon cancer in the literature. This is the first case report of acrokeratosis paraneoplastica associated with early colon cancer.- - - - - - - - - - ranking = 1keywords = acrokeratosis (Clic here for more details about this article) |
2/10. Bullous lesions in Bazex syndrome and successful treatment with oral psoralen phototherapy.A 59-year-old man presented with a psoriasiform dermatitis with associated bullae and destructive nail dystrophy of the hands and feet. He had lost 10 kg weight over 6 months and a mass in the neck was noted. He was provisionally diagnosed with Bazex syndrome (acrokeratosis paraneoplastica) and subsequent investigations revealed a squamous cell carcinoma in the right piriform fossa. His skin lesions were treated with oral psoralen and ultraviolet A phototherapy and this cleared the cutaneous changes, but the nail changes have persisted at 18 months follow up.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
3/10. Coexistence of Darier's disease and acrokeratosis verruciformis of Hopf.Darier's disease and acrokeratosis verruciformis are inherited with the same pattern and they share similar clinical properties. We present a patient with both Darier's disease and acrokeratosis verruciformis. The patient had had brownish and skin-colored papules, initially on her face and neck, since the age of 25. Similar lesions had gradually spread to various parts of her body and lastly the dorsal aspect of her feet. On dermatological examination, brownish and skin-colored, 2 to 5 mm, keratotic papules were observed on her face, neck, both axillae, inframammary regions, and dorsa of the hands and feet. The nail examination revealed "V" shaped notches and longitudinal ridges on the fingers of both hands. The biopsy taken from the neck showed typical findings for Darier's disease. The biopsy from the dorsa of the left foot revealed the distinctive structures of acrokeratosis verruciformis. In this article the clinical and histopathological findings of these diseases are reviewed based on our patient.- - - - - - - - - - ranking = 13.538396700195keywords = acrokeratosis verruciformis, acrokeratosis, verruciformis (Clic here for more details about this article) |
4/10. Bazex syndrome (paraneoplastic acrokeratosis).Bazex syndrome (paraneoplastic acrokeratosis) is characterized by the presence of hyperkeratotic lesions on the nose, ears, palms, and soles that appear in association with malignancies of the upper aerodigestive tract, most often a squamous cell carcinoma. We present a case of Bazex syndrome and provide a review of the literature.- - - - - - - - - - ranking = 2.5keywords = acrokeratosis (Clic here for more details about this article) |
5/10. Unusual association between acrokeratosis verruciformis of Hopf and multiple keratoacanthomas. Successful therapy with acitretin.A 62-year-old man presented with the unusual association of acrokeratosis verruciformis of Hopf and multiple keratoacanthomas. Both conditions were treated successfully with acitretin.- - - - - - - - - - ranking = 9.6702833572824keywords = acrokeratosis verruciformis, acrokeratosis, verruciformis (Clic here for more details about this article) |
6/10. Cutaneous paraneoplastic syndrome (acrokeratosis paraneoplastica) preceding squamous cell carcinoma of the glottic larynx.paraneoplastic syndromes that occur in the minority of cancer patients are the produced signs and symptoms at distant sites from the tumour or its metastases. These syndromes may occur due to the production of substances by tumoural lesions that directly or indirectly cause distant symptoms or depletion of normal substances or host response to the tumours. A paraneoplastic syndrome may be the first sign of a malignancy so its recognition may be critical for early cancer detection. Most of the paraneoplastic syndromes associated with head and neck tumours are endocrinologic or neurologic; dermatologic syndromes are less common. head and neck cancers also have occasionally been reported in association with paraneoplastic syndromes and to date there are only a few cases in the literature about the presence of a cutaneous paraneoplastic syndrome as the first manifestation of a laryngeal cancer, especially glottic larynx cancer. A wide variety of cutaneous syndromes are associated with malignancies and these syndromes may precede, follow, or be concurrent with the underlying malignancy. In this report we present a case with cutaneous syndrome of acrokeratosis paraneoplastica preceding squamous cell carcinoma of glottic larynx, and review the other cutaneous paraneoplastic syndromes reported in the literature.- - - - - - - - - - ranking = 2.5keywords = acrokeratosis (Clic here for more details about this article) |
7/10. Acrokeratosis paraneoplastica (Bazex's syndrome): association with liposarcoma.Acrokeratosis paraneoplastica (Bazex's syndrome) is a rare obligate paraneoplastic dermatosis characterized by erythematosquamous lesions localized symmetrically at the acral sites. The condition almost exclusively affects Caucasian men older than 40 years. It is usually associated with primary malignant neoplasms of the upper aerodigestive tract. In most cases, the skin changes precede the clinical manifestation of the underlying neoplasm. The dermatosis can be cured only by removal of the underlying carcinoma. We describe a case of acrokeratosis paraneoplastica associated with a retroperitoneal liposarcoma in a 71-year-old Caucasian man. The liposarcoma was surgically removed but recurred several times, with acrokeratosis paraneoplastica showing a parallel development. We, therefore, add liposarcoma to the growing list of malignant neoplasms associated with acrokeratosis paraneoplastica.- - - - - - - - - - ranking = 1.5keywords = acrokeratosis (Clic here for more details about this article) |
8/10. Bazex syndrome (acrokeratosis paraneoplastica).A 67 year old woman with an extensive oropharyngeal carcinoma developed acrokeratosis paraneoplastica. She suffered severe pain in the fingers and toes and experienced some symptomatic relief with psoralen ultraviolet A therapy.- - - - - - - - - - ranking = 2.5keywords = acrokeratosis (Clic here for more details about this article) |
9/10. Acrokeratosis paraneoplastica (Bazex syndrome) with oropharyngeal squamous cell carcinoma.A 65-year-old white man presented with all the clinical features of acrokeratosis paraneoplastica of Bazex, characterized by violaceous erythema and scaling of the nose, aural helices, fingers, and toes, with keratoderma and severe nail dystrophy. Examination of the patient for possible associated malignancy disclosed an asymptomatic squamous cell carcinoma at the oropharyngeal region. The skin lesions resolved almost completely following radiation therapy of the neoplasm, but the onychodystrophy persisted. This case report illustrates the importance of early recognition of Bazex syndrome.- - - - - - - - - - ranking = 0.5keywords = acrokeratosis (Clic here for more details about this article) |
10/10. Bazex syndrome (acrokeratosis paraneoplastica).Acrokeratosis paraneoplastica (Bazex syndrome) is a rare but distinctive dermatosis associated with carcinomas of the upper aerodigestive tract with possible cervical lymph node metastases. The cutaneous lesions occurring in the syndrome are non-metastatic skin involvement that parallels (as cutaneous marker) the evolution of the malignancy. Since only a few case reports have been published in the otolaryngologic literature, we present our experience and review some of the findings previously reported.- - - - - - - - - - ranking = 2keywords = acrokeratosis (Clic here for more details about this article) |
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