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1/6. bacteremia and endocarditis caused by a Gordonia species in a patient with a central venous catheter.

    We report the first case of endocarditis caused by a Gordonia species genetically related to G. sputi but exhibiting some atypical biochemical features in a 31-year-old woman with a central venous catheter. This unusual pathogen may be a new cause of opportunistic infections in patients with severe underlying diseases.
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ranking = 1
keywords = opportunistic infection
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2/6. Medical management of pneumonia caused by rhodococcus equi in a renal transplant recipient.

    rhodococcus equi is an animal pathogen that occasionally causes opportunistic infections in immunocompromised patients. The most common clinical picture is one of necrotizing pneumonia with a tendency toward cavitation and the formation of abscesses. We report a case of pneumonia caused by R equi in a renal transplant patient. An excellent response was shown to antibiotic treatment. Symptoms regressed, and the progressive disappearance of the lesion was confirmed on follow-up computed tomography scans. Surgical intervention or other invasive procedures were not required. To our knowledge, 14 cases of infection by R equi in solid-organ transplant patients have been described to date. Nine were recipients of a renal allograft. Surgery was required in many of these patients, and all the renal transplant recipients required the use of invasive therapeutic techniques, such as pleural drainage. This is the first case of a renal transplant recipient in whom radiologic presentation was as a solid nodule without ensuing cavitation that resolved exclusively with antibiotic treatment.
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ranking = 1
keywords = opportunistic infection
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3/6. Catheter-related bacteremia due to Kocuria rosea in a patient undergoing peripheral blood stem cell transplantation.

    BACKGROUND: micrococcus species may cause intracranial abscesses, meningitis, pneumonia, and septic arthritis in immunosuppressed or immunocompetent hosts. In addition, strains identified as micrococcus spp. have been reported recently in infections associated with indwelling intravenous lines, continuous ambulatory peritoneal dialysis fluids, ventricular shunts and prosthetic valves. CASE PRESENTATION: We report on the first case of a catheter-related bacteremia caused by Kocuria rosea, a gram-positive microorganism belonging to the family micrococcaceae, in a 39-year-old man undergoing peripheral blood stem cell transplantation due to relapsed hodgkin disease. This uncommon pathogen may cause opportunistic infections in immunocompromised patients. CONCLUSIONS: This report presents a case of Kocuria rosea catheter related bacteremia after stem cell transplantation successfully treated with vancomycin and by catheter removal.
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ranking = 1
keywords = opportunistic infection
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4/6. empyema caused by kingella denitrificans and peptostreptococcus spp. in a patient with bronchogenic carcinoma.

    empyema caused by kingella denitrificans and peptostreptococcus spp. was diagnosed in a patient with bronchogenic carcinoma. This appears to be the third report providing evidence of a pathogenic role for K. denitrificans, and the first concerning infection in the pleural space and in a patient with underlying immunosuppressive disease. K. denitrificans should be added to the list of fastidious gram-negative bacteria associated with opportunistic infections in the compromised host.
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ranking = 1
keywords = opportunistic infection
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5/6. rhodococcus equi pneumonia. An unusual early manifestation of the acquired immunodeficiency syndrome (AIDS).

    Infection with rhodococcus equi has been reported as an occasional cause of cavitary pneumonia in severely immunocompromised patients, including those with the acquired immunodeficiency syndrome (AIDS). We report two cases of R equi pneumonia presenting in one month in patients infected with human immunodeficiency virus (hiv) who had not previously had an opportunistic infection. The clinical and radiographic manifestations of the disease are distinctive and should suggest the diagnosis. R equi pneumonia in a person with hiv infection should be considered diagnostic of AIDS. Recognition of this entity is important since antibiotic therapy is different from that conventionally used in pneumonias in AIDS patients and must be prolonged.
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ranking = 1
keywords = opportunistic infection
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6/6. Uncommon manifestations of opportunistic infections in an hiv infected patient.

    A case of an hiv infected patient complicated with penicillium marneffei and rhodococcus equi infection is reported. He presented with chronic ulcer as pyoderma gangrenosum-like on his right calf and submandibular lymphadenitis as scrofuloderma-like. penicillium marneffei and rhodococcus equi were isolated from the ulcer and lymph node respectively.
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ranking = 4
keywords = opportunistic infection
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