1/3. Clear cell adenocarcinoma of the male urethra.We present a rare case of clear cell adenocarcinoma of the male urethra. These tumors are usually presented with hematuria, obstructive voiding symptoms or urinary retention. Histologically, they display tubulocystic, tubular, papillary or diffuse patterns with clear and hobnail cells. The present case of this rare disease emphasizes the aggressive nature of urethral clear cell adenocarcinoma in males.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/3. Clear cell carcinoma arising in a cesarean section scar. Report of a case with fine needle aspiration cytology.BACKGROUND: Clear cell carcinoma arising in a cesarean section scar is an extremely rare disease. To the best of our knowledge, there is no published report on the aspiration cytology. CASE: A 56-year-old woman presented with a mass in a cesarean section scar. Initially an abdominal desmoid was considered, but the features of fine needle aspiration (FNA) cytology suggested an adenocarcinoma. The resected tumor was histologically composed of clear cell carcinoma showing cystic, solid and papillary patterns. CONCLUSION: FNA cytology of masses arising in a surgical scar can be a useful tool in obtaining an accurate pathologic diagnosis of a malignant neoplasm.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/3. Vaginal clear cell carcinoma in a young patient with ectopic termination of the left ureter in the vagina.The association of clear cell adenocarcinoma of the vagina and vaginal adenosis with prenatal exposure to diethylstilbestrol (DES) is well-documented in the united states. In europe, however, DES was never used in the therapy of threatened abortion and, therefore, clear cell adenocarcinoma and vaginal adenosis remained rare diseases. We report on the clinical and pathological features of a case of clear cell adenocarcinoma of the upper vagina in a 17-year-old German girl, who had a history of hypoplasia of the left kidney with an ectopic termination of the ureter in the upper vagina, removed surgically 2 years before. No previous report of a similar coincidence of vaginal clear cell carcinoma and a congenital disorder of the genitourinary tract exists. Congenital anomaly of the ureter interfering with the development and the differentiation of the distal Mullerian tract and its epithelium might have provided a similar histological basis for carcinogenesis in our patient to that in those provided exposed to DES.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |