1/24. Mucinous tumor of the gallbladder with a separate nodule of anaplastic carcinoma.A case of mucinous tumor of the gallbladder with a separate nodule of anaplastic carcinoma is reported. The patient was an 83-year-old Japanese man who underwent cholecystectomy under the preoperative diagnosis of a mucus-producing gallbladder tumor. A mucinous tumor was found in the neck and distal body of the gallbladder, associated with a separate nodule in the fundus. The latter nodule was initially diagnosed as a benign xanthogranulomatous lesion. However, the immunohistochemical study revealed that the atypical cells in the superficial part of the nodule were positive for cytokeratin and epithelial membrane antigen, confirming the diagnosis of anaplastic carcinoma. Although the occurrence of mural nodules in mucinous cystic tumors of the ovary and pancreas is well reported, to our knowledge, this is the first report on the occurrence of a mucinous tumor with a nodule of anaplastic carcinoma in the gallbladder.- - - - - - - - - - ranking = 1keywords = gallbladder (Clic here for more details about this article) |
2/24. Unusual origins of pseudomyxoma peritonei.pseudomyxoma peritonei is a rare neoplastic condition in that gelatinous intraperitoneal fluid collections and mucinous implants on the peritoneal surfaces and omentum are found. The pathological origin is usually an adenoma or well-differentiated adenocarcinoma of the appendix. A smaller number of cases arises from ovarian tumors. We report two unusual cases of pseudomyxoma peritonei. As a child, the first patient underwent several surgical procedures of the large bowel to relieve the consequences of hirschsprung disease that were complicated by recurrent enteric fistulae. Colonic epithelial cells, with neoplastic changes due to chronic inflammation in the presence of enteric fistulae, were probably dislocated during these episodes, causing pseudomyxoma peritonei. In the second patient, pseudomyxoma was caused by intraperitoneal seeding of a mucinous urachal adenocarcinoma. We hypothesize that seeding of mucus producing epithelial cells into the abdominal cavity may result in this rare entity called pseudomyxoma peritonei, regardless of the source.- - - - - - - - - - ranking = 8.8745577523413E-5keywords = inflammation (Clic here for more details about this article) |
3/24. Usefulness of MR imaging in the postsurgical monitoring of gallbladder cancer in a patient with bile duct cancer that developed 7 years after resection of mucinous adenocarcinoma of the gallbladder.We encountered a case of left hepatic duct cancer that developed 7 years after surgical resection of early-stage adenocarcinoma of the gallbladder. A 65-year-old woman was hospitalized with high fever and general fatigue. She also had elevated serum levels of alkaline phosphatase, gamma-glutamyltranspeptidase, and carbohydrate antigen 19-9. Seven years earlier, she had undergone extended cholecystectomy and resection of the extrahepatic bile duct for early-stage mucinous adenocarcinoma of the gallbladder. Conventional examinations did not reveal any responsible lesions. Magnetic resonance (MR) cholangiography, however, showed a tumor obstructing the left hepatic duct, and dynamic MR images revealed multiple foci of bacterial abscess in the liver. Surgically resected tissue again revealed mucinous adenocarcinoma. The present case is rare in that metachronous mucinous adenocarcinoma of the biliary system occurred after a long interval. This case suggests the usefulness of MR imaging in the postsurgical monitoring of patients with gallbladder carcinoma.- - - - - - - - - - ranking = 1.375keywords = gallbladder (Clic here for more details about this article) |
4/24. Mucin-producing carcinoma of the gallbladder: imaging demonstration in four cases.We report four cases of mucin-producing carcinoma of the gallbladder (three papillary adenocarcinomas and one mucinous carcinoma), with an emphasis on imaging features. Our findings suggest that when a papillary protrusion or thickened wall, including cystic areas and/or calcifications, is seen radiologically in the enlarged gallbladder, mucin-producing carcinoma of the gallbladder should be included in the differential diagnosis.- - - - - - - - - - ranking = 0.875keywords = gallbladder (Clic here for more details about this article) |
5/24. Gastric adenocarcinoma presenting as an eyelid and conjunctival mass.A 50-year-old white man complained of "inflammation" of his right eyelid since January 1989. In June 1990, he had undergone a gastrectomy for an adenocarcinoma of the stomach. In August 1990, his right eye showed a painless, firm infiltration of the upper and lower lid, ulceration and loss of eyelashes of the upper lid and a reddish, subepithelial thickening of the medial bulbar conjunctiva. Biopsies of the right upper lid and nasal bulbar conjunctiva disclosed a metastatic, poorly differentiated adenocarcinoma of the stomach (signet ring cell carcinoma) both in the lid and conjunctival biopsies. carcinoembryonic antigen (CEA) was detected in the tumor cells. Electron microscopic examination revealed tumor cells with signs of secretory activity. Although metastases to the eyelids and conjunctiva are rare, they may precede the clinical manifestation of the primary tumor for months or even years. In patients with chronic, recalcitrant lesions of eyelids or conjunctiva, especially if accompanied by loss of eyelashes, a primary or secondary malignancy should be excluded by early biopsies and histopathological examination.- - - - - - - - - - ranking = 8.8745577523413E-5keywords = inflammation (Clic here for more details about this article) |
6/24. Mucinous adenocarcinoma arising in rectovaginal fistulas associated with Crohn's disease.BACKGROUND: Crohn's disease is a chronic inflammatory disorder characterized by focal, transmural inflammation of the intestine. Gynecologic involvement, including rectovaginal fistula formation, is frequent. Case #1. A 53-year-old female with a 30-year history of Crohn's disease and numerous perirectal fistulas developed a foul smelling, purulent drainage from her rectum and a mucopurulent, bloody discharge from her vagina. A lower vaginal lesion biopsy demonstrated a low-grade mucinous adenocarcinoma. Case #2. A 42-year-old female with a 15-year history of Crohn's disease developed drainage from her vagina. physical examination revealed an enlarging mass involving the posterior wall of the vaginal vault that connected to the anus by a fistula tract. A biopsy revealed mucinous adenocarcinoma. CONCLUSIONS: Malignant transformation of persistent rectovaginal fistulas is a potential complication of Crohn's disease.- - - - - - - - - - ranking = 8.8745577523413E-5keywords = inflammation (Clic here for more details about this article) |
7/24. Metastatic appendiceal adenocarcinoma presenting late as epididymo-orchitis: a case report and review of literature.BACKGROUND: Whereas testicular metastases are in themselves a rare entity, testicular secondaries from an appendiceal carcinoma have not yet been described. The case also illustrates the diagnostic dilemma of a tumour presenting as epididymo-orchitis. CASE PRESENTATION: The authors present a case of an appendiceal carcinoma that, two years after radical therapy, manifested as a secondary in the testis. It was misdiagnosed as an epididymo-orchitis and was only revealed through histology. CONCLUSIONS: Practitioners need to remember that long-standing testicular inflammation may result form secondary tumours. Even "exotic" primary tumours in the medical history of the patient must give rise to an increased suspicion threshold.- - - - - - - - - - ranking = 8.8745577523413E-5keywords = inflammation (Clic here for more details about this article) |
8/24. Imaging findings in mucin-producing carcinoma of the gallbladder.Mucin-producing carcinoma of the gallbladder is rare, and its imaging features have not been well documented. Its symptoms and signs are nonspecific and the prognosis of the disease is poor. We present a 73-year-old male with mucin-producing carcinoma of the gallbladder, emphasizing its imaging features on ultrasound, computed tomography and magnetic resonance imaging. The tumor usually presents as a cauliflower-like soft tissue mass with small calcified spots in the gallbladder wall and some laminated high viscosity fluid inside the gallbladder cavity. Recognition of these features can provide clues to the diagnosis of mucin-producing carcinoma of the gallbladder.- - - - - - - - - - ranking = 1.125keywords = gallbladder (Clic here for more details about this article) |
9/24. Composite endocrine cell, typical adenocarcinoma and signet ring carcinoma of the gallbladder.The authors report a case of composite tumor of the gallbladder which exhibited features of both adenocarcinoma (with typical areas, signet ring cells and clear cells) and endocrine cell carcinoma. The histological picture suggests the origin of both components in a common primitive cell with the capacity to differentiate to different types of metaplastic epithelium and supports the hypothesis of a sequence metaplasia--dysplasia--carcinoma.- - - - - - - - - - ranking = 0.625keywords = gallbladder (Clic here for more details about this article) |
10/24. Mucinous adenocarcinoma of the temporal region initially diagnosed as temporomandibular disorders: a case report.adenocarcinoma occurring in the temporal region has not previously been reported. We present a case of mucinous adenocarcinoma of the temporal region. A 62-year-old female patient was diagnosed as having temporomandibular disorders because of severe trismus and joint pain. Although trismus progressively worsened, there were no abnormal findings on diagnostic imaging studies including magnetic resonance imaging (MRI) and bone scintigraphy. As swelling of the temporal region was observed, biopsy was performed. Histologic examination showed chronic inflammation of the striated muscle. Approximately 6 months later, follow-up MRI demonstrated an ill-defined mass lesion in the infratemporal region extending to the intracranium. Histologic diagnosis of the biopsy showed that this mass lesion was moderately differentiated mucinous adenocarcinoma.- - - - - - - - - - ranking = 8.8745577523413E-5keywords = inflammation (Clic here for more details about this article) |
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