Cases reported "Adrenal Gland Diseases"

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1/11. The incidentally discovered asymptomatic adrenal tuberculous mass mimicking malignancy.

    Tuberculous adrenal mass without any tuberculous changes in other sites is a rare entity. In this study we describe such a case. A male patient of 47 years with 6 months history of anorexia and weakness was presented. ultrasonography and computed tomography revealed a mass in the right adrenal gland. It was mistaken as a malignant neoplasm and the diagnosis was confirmed by surgical exploration.
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keywords = neoplasm
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2/11. Clitoral cyst as a cause of ambiguous genitalia.

    BACKGROUND: Ambiguous genitalia need appropriate evaluation, because a serious disease can manifest as this condition. CASE: A 28-year-old woman was referred with a "penis" present from age 12 years that enlarged throughout puberty but recently was unchanged. Differential diagnosis included true hermaphroditism; adrenal hyperplasia; clitoral, ovarian, and adrenal neoplasms; stromal hyperthecosis; polycystic ovarian syndrome; and exogenous androgen exposure. Free testosterone was not elevated. dehydroepiandrosterone sulfate, 17-hydroxyprogesterone, total testosterone, androstenedione, deoxycorticosterone, 11-deoxycortisol, chromosomal analysis (46,XX), an intravenous pyelogram, and pelvic ultrasound were normal. The patient elected surgical removal. The mass was a chronic inflamed epidermoid cyst. CONCLUSION: If this patient had been appropriately evaluated earlier, she would have been spared anxiety and embarrassment over a simple epidermoid cyst.
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ranking = 1
keywords = neoplasm
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3/11. Idiopathic unilateral adrenal hematoma: report of a case.

    We report an unusual case of idiopathic unilateral adrenal hematoma, which was asymptomatic and unaccompanied by a hematologic disorder. The surgical specimen contained a large tumor comprised of subacute to chronic organized hematoma. The preoperative magnetic resonance imaging findings were compatible with characteristics reported previously, except for spotty strong enhancement in the peripheral part of the mass. It is important to differentiate this benign lesion from a neoplasm, although we were not able to identify it preoperatively and a precise diagnosis was only confirmed when the resected specimen was examined pathologically.
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ranking = 1
keywords = neoplasm
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4/11. Bilateral benign haemorrhagic adrenal cysts in beckwith-wiedemann syndrome: case report.

    beckwith-wiedemann syndrome is the most common overgrowth malformation syndrome. The classical features include macrosomia, macroglossia, omphalocele and ear lobe anomalies. Among the associated adrenal anomalies, foetal cortical cytomegaly, outer cortical haemorrhage and unilateral benign cysts are well described. A term neonate was admitted with typical features of the syndrome. Radiological evaluation revealed a rare association of bilateral benign hamorrhagic adrenal cysts. Serial sonography confirmed hamorrhage into benign cysts and ruled out neoplasms. Only one similar case has been documented in the literature previously.
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ranking = 1
keywords = neoplasm
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5/11. Sustentaculoma: report of a case of a distinctive neoplasm of the adrenal medulla.

    A case of a morphologically distinctive tumor of the adrenal medulla occurring in a 54-year-old woman is described. On microscopic examination, the tumor was well circumscribed and characterized by the presence of ill-defined, irregular nests of spindle cells with oval to elongated nuclei, tiny nucleoli, and abundant eosinophilic cytoplasm. The tumor was associated with a moderate infiltrate of lymphocytes and plasma cells with occasional lymphoid follicles. necrosis, marked cellular atypia, and mitoses were absent. Immunohistochemical studies demonstrated the tumor cells to be strongly reactive for vimentin, S-100 protein, and CD56, and nonreactive for glial fibrillary acidic protein, chromogranin, synaptophysin, melanoma-associated antigens, and dendritic cell markers. Ultrastructural examination showed elongated cells with interdigitating cytoplasmic processes devoid of a basal lamina. No secretory granules were noted. The morphology, immunophenotype, and ultrastructure of this unique neoplasm suggest derivation from sustentacular cells of the adrenal medulla. We propose the designation "sustentaculoma" for this hitherto undescribed neoplasm of the adrenal gland.
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ranking = 6
keywords = neoplasm
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6/11. Massive adrenal hemorrhage secondary to metastatic lung carcinoma.

    The adrenal glands are frequently metastatic sites of lung and other primary neoplasms. These metastases are usually clinically occult and secondary adrenal hemorrhage is extremely rare. Two patients who developed massive adrenal hemorrhage secondary to metastatic lung carcinoma to the adrenal glands are presented.
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ranking = 1
keywords = neoplasm
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7/11. Massive adrenal haemorrhage complicating adrenal neoplasm.

    Two patients presented to hospital with clinical features of acute retroperitoneal haemorrhage. In each case, laparotomy revealed massive adrenal haemorrhage, and histological evidence of underlying neoplasia was eventually found.
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ranking = 4
keywords = neoplasm
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8/11. Primary adrenal insufficiency manifesting as malignant lymphoma.

    Primary adrenal insufficiency associated with a hematologic malignant neoplasm is a rare entity. Most malignant neoplasms with metastases to the adrenal gland are secondary to solid carcinomas of the lung and breast. A 55-year-old man was seen with clinical and biochemical evidence of primary adrenal insufficiency as the initial manifestation of his malignant lymphoma. At autopsy the architecture of both adrenal glands was completely effaced by malignant plasmacytoid cells. This case emphasizes that infiltrative lymphoma of the abdomen is a rare cause of primary adrenal insufficiency and may be the initial manifestation. Furthermore, it should be included in the differential diagnosis.
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ranking = 2
keywords = neoplasm
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9/11. Malakoplakia of the adrenal gland.

    The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it is suggested that malakoplakia is due to an abnormal macrophage response to E coli infection.
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ranking = 1
keywords = neoplasm
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10/11. Spontaneous retroperitoneal hemorrhage: a diagnostic challenge.

    Spontaneous retroperitoneal hemorrhage can present a difficult diagnostic dilemma. We present 4 illustrative cases within the last 2 years at our institutions. Excluding traumatic injury to the retroperitoneum and abdominal aortic aneurysms, about 75 per cent of the cases are related to neoplasms or vascular anomalies. An awareness of predisposing disease states is important. A high index of suspicion and an aggressive diagnostic approach are necessary. If evaluation does not disclose an etiology for retroperitoneal hemorrhage then non-operative management may be considered. This is especially true if an underlying systemic condition is present.
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ranking = 1
keywords = neoplasm
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