1/9. Mushroom worker's lung resulting from indoor cultivation of pleurotus osteatus.Indoor cultivation of oyster mushroom pleurotus osteatus lead to an outbreak of extrinsic allergic alveolitis in two workers. High titer of indirect fluorescent antibody and positive precipitins against basidiospores of P. osteatus were demonstrated in sera of the patients. Mushroom workers should protect themselves from the basidiospores, being aware of their pathogenicity.- - - - - - - - - - ranking = 1keywords = alveolitis (Clic here for more details about this article) |
2/9. hypersensitivity pneumonitis induced by the spore of pleurotus Eryngii (Eringi).We reported the first case of hypersensitivity pneumonitis (HP) by an edible mushroom, pleurotus Eryngii (Eringi). A 54-year-old woman had worked in a Bunashimeji mushroom factory for 42 months, and she moved to a new factory producing Eringi. Two months after, she was found to have HP by the spore of Eringi. Although no radiological finding was detected 6 months before the onset of HP, serum surfactant protein D (SP-D) had been elevated. We speculated that type II pneumocyte activation might prepare the ground for HP during the former exposure to Bunashimeji, and serum SP-D levels might reflect their conditions.- - - - - - - - - - ranking = 4.4261876423782keywords = pneumonitis (Clic here for more details about this article) |
3/9. hypersensitivity pneumonitis due to occupational inhalation of fungi-contaminated corn dust.hypersensitivity pneumonitis or extrinsic allergic alveolitis can be defined as a lung disease caused by a wide group of antigens that reach the lung by inhalation of organic and/or inorganic dust of various sources. The dust of the stored maize corn has been reported as cause of respiratory symptoms. During the storage process, maize corn dust can be contaminated by moulds and thermophilic actinomycetes, which have not been described until now as the causing antigens of these symptoms. We present a case of occupational hypersensitivity pneumonitis in an agricultural worker who cultured and stored maize corn. Clinical findings, precipitating antibodies, and evolution after having removed him from his work, confirmed the diagnosis. In our case, Aspergillus species contaminating the maize corn dust are probably the antigens that caused the disease.- - - - - - - - - - ranking = 6.3114251708538keywords = alveolitis, pneumonitis (Clic here for more details about this article) |
4/9. Acute toxic pneumonitis complicating chronic obstructive pulmonary disease (COPD) in a farmer.BACKGROUND: Toxic pneumonitis or Organic dust Toxic syndrome (ODTS) is a common, usually self-limiting condition among agricultural workers, occurring after high level exposure to agricultural dust. CASE REPORT: We describe the case of a 68-year-old smoker and farmer who became ill with dyspnea, flu-like symptoms, and hypoxia after cleaning out a grain bin. RESULTS: Chest radiograph was normal. He was treated with steroids, antibiotics, and oxygen supplementation and recovered over 3 months, but continues with lingering exercise intolerance after 2 years. DISCUSSION: Although toxic pneumonitis usually follows a relatively benign course with spontaneous recovery and no permanent sequale it can lead to the exacerbation of underlying lung conditions, resulting in incomplete or delayed recovery. Prevention is aimed at limiting exposure by avoidance, by increasing ventilation in closed spaces and by appropriate use of personal protective equipment.- - - - - - - - - - ranking = 5.3114251708538keywords = pneumonitis (Clic here for more details about this article) |
5/9. Successful treatment of hypersensitivity pneumonitis caused by grifola frondosa (Maitake) mushroom using a HFA-BDP extra-fine aerosol.We successfully treated a patient with occupational hypersensitivity pneumonitis (HP) caused by grifola frondosa (Maitake) mushroom spore with an extra-fine aerosol corticosteroid; beclomethasone dipropionate (BDP) dissolved in hydrofluoroalkane-134a (HFA). A 49-year-old woman developed respiratory symptoms 3 months after beginning work on a mushroom farm. She was diagnosed as HP based on radiological and serological findings. Oral prednisolone therapy improved her HP and she returned to the same farm. Her HP relapsed after 5 months, and daily 400 microg of HFA-BDP was administered with gradual improvement. An extra-fine particle inhaled corticosteroid might reach appropriate alveoli to be effective therapy for mild HP.- - - - - - - - - - ranking = 4.4261876423782keywords = pneumonitis (Clic here for more details about this article) |
6/9. hypersensitivity pneumonitis induced by spores of penicillium citrinum in a worker cultivating Enoki mushroom.A 47-year-old Japanese woman was admitted to our hospital with a 2-week history of dry cough and shortness of breath. She had been engaged in Enoki mushroom production for 22 years. Chest X-ray and chest computed tomography (CT) scan showed bilateral fine-nodular shadows and ground glass opacity. bronchoalveolar lavage fluid demonstrated an increase of total cell counts with predominant lymphocytosis. Pathological specimens obtained by video-assisted thoracoscopic surgery revealed alveolitis and noncaseating granuloma with giant cells. Lymphocyte stimulation test showed positive responses with Enoki mushroom, culture medium, and penicillium citrinum. On double immunodiffusion test, a precipitation line was observed between patient's serum and penicillium citrinum antigen. She was found to have hypersensitivity pneumonitis caused by penicillium citrinum. This is the first report of mushroom worker's lung caused by penicillium citrinum.- - - - - - - - - - ranking = 5.4261876423782keywords = alveolitis, pneumonitis (Clic here for more details about this article) |
7/9. hypersensitivity pneumonitis and extrinsic asthma. An unusual association.A farmer who had no prior history of pulmonary disease developed tightness in the chest of rapid onset, shortness of breath, fever, and pulmonary infiltration while farming. The symptoms of his disease worsened with repeated exposure to the dusty farm field but remitted after each of five hospitalizations. Provocative challenge with inhalation of a water-soluble extract of dust from the field reproduced both asthmatic and pneumonitic features of the disease, while administration of corticosteroids clinically controlled the entire process. The data suggest a common cause for asthma and pneumonitis in this patient.- - - - - - - - - - ranking = 4.4261876423782keywords = pneumonitis (Clic here for more details about this article) |
8/9. hypersensitivity pneumonitis resulting from aspergillus fumigatus in a greenhouse.A 57-y-old female who had cultivated vegetables in a plastic greenhouse developed a case of hypersensitivity pneumonitis from aspergillus fumigatus. This report exemplifies a potential hazard caused by a thermotolerant fungus, A. fumigatus, in a poorly constructed greenhouse.- - - - - - - - - - ranking = 4.4261876423782keywords = pneumonitis (Clic here for more details about this article) |
9/9. hypersensitivity pneumonitis in peat moss processing plant workers.A nonsmoking 54-yr-old man, employed in a peat moss packaging plant, developed dyspnea and recurrent fever. The diagnosis of hypersensitivity pneumonitis (HP) was made. Thirteen of 14 coworkers and 13 nonexposed control subjects were studied. Five workers were nonsmokers, two were minimal smokers, and six were smokers. HP was found in another subject. Monocillium sp. and penicillium citreonigrum, 4.6 x 10(7) CFU/g, were found in the peat moss. Three nonsmokers, the two minimal smokers (including the subject with HP), and the index case had antibodies to these microorganisms; none of the six heavy smokers had antibodies. serum TNF-alpha was higher in the workers than in the control subjects (0.930 /- 0.177 versus 0. 350 /- 0.076). Three of the four asymptomatic seropositive workers and two seronegative smokers were further evaluated. All three seropositive workers had normal lung functions and CT but they all had a lymphocytic alveolitis (30, 34, and 68% lymphocytes in their bronchoalveolar lavage [BAL]). The smokers had normal lung functions, CT, and percentage of BAL lymphocytes (3 and 13%). This study identified a previously unrecognized work environment that can lead to HP and documented a protective effect of smoking on the response to antigens.- - - - - - - - - - ranking = 5.4261876423782keywords = alveolitis, pneumonitis (Clic here for more details about this article) |