1/3. Ketoalkalosis as a result of triple derangement of acid-base equilibrium in a diabetic patient.A diabetic patient presented with weight loss, ketosis, and hyperventilation, thus mimicking the clinical picture of diabetic ketoacidosis. Laboratory investigations revealed alkalemia and a pattern consistent with a triple derangement of acid-base equilibrium: respiratory alkalosis, metabolic acidosis and metabolic alkalosis. High cortisol level suggested a genesis of ketosis different from diabetes mellitus. The patient died suddenly from acute gastrointestinal bleeding. autopsy showed a carcinoma of the head of the pancreas with secondary portal hypertension and rupture of varices. Pulmonary micrometastases were demonstrated. It is suggested that stress hormones were the main cause of the 'ketoalkalotic' pattern observed.- - - - - - - - - - ranking = 1keywords = ketosis, ketoacidosis (Clic here for more details about this article) |
2/3. Diabetic ketoalkalosis.The usual metabolic derangement in uncontrolled diabetes mellitus is metabolic acidosis, with an increase in the anion gap because of increased ketoacids and lactate. However, diabetic ketoalkalosis may occasionally be encountered, the prominent clinical feature of which is vomiting, with depletion of potassium, chloride, and hydrogen ions. Self-medication with absorbabe alkali may also contribute to the alkalosis. It would be dangerous to treat hyperlgycemic patients with alkali if their condition is ketoalkalosis instead of ketoacidosis.- - - - - - - - - - ranking = 0.040645436915263keywords = ketoacidosis (Clic here for more details about this article) |
3/3. Salicylate-induced hypoglycemia and ketoacidosis in a nondiabetic adult.A 78-year-old nondiabetic woman was admitted to the hospital with salicylate-induced hypoglycemia. ketosis was present with a moderate metabolic acidosis and primary respiratory alkalosis. The patient's mental status improved immediately following intravenous administration of glucose. The case illustrates salicylate's hypoglycemic activity, and that the metabolic acidosis may have exacerbated symptoms of cerebral glucopenia.- - - - - - - - - - ranking = 0.16258174766105keywords = ketoacidosis (Clic here for more details about this article) |