1/6. Tufted hair folliculitis associated with pemphigus vulgaris.Tufted hair folliculitis (THF) is a rare disease which is characterized by the emergence of multiple hairs from widely dilated follicular orifices surrounded by an inflammatory infiltrate resulting in scarring alopecia. The pathogenesis is not yet fully understood. Although colonization with staphylococcus aureus could not always be detected and systemic treatment with antibiotics alone is not sufficient, this microorganism is considered to play an important role. Around 30 patients with THF have been reported since the first publication. We present a patient with pemphigus vulgaris who developed THF. To our knowledge, this is the fourth case with an association of these two entities. Amongst other causing mechanisms, the autoimmune reaction may play an important role for the development of THF.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/6. Lipedematous alopecia of the scalp.Lipedematous scalp is a rare disorder, mainly described in adult African-American females. We report 2 adult caucasian males with lipedematous scalp associated with androgenetic alopecia. patients were studied by dermoscopy and histopathology; they were treated with finasteride 1 mg. In our patients, lipedematous scalp affected the occipital and the vertex areas and pathologically exhibited mild edema and thickening of the adipose subcutaneous layer. At videodermoscopy, lipedematous scalp areas showed linear areas of teleangiectasia within the scalp creases, possibly caused by compression of the superficial blood capillaries by the increased volume of the subcutaneous fat layer within the thickened scalp. finasteride at a dose of 1 mg per day for 1 year induced mild improvement of androgenetic alopecia in one patient and stabilization of the disease in the other. The lipedematous scalps remain unchanged. Lipedematous scalp is apparently a rare disease even though the condition is probably underdiagnosed. As a matter of fact, we diagnosed lipedematous scalp in our patients during a clinical examination for androgenetic alopecia, which was the patients' complaint. The association of lipedematous scalp and androgenetic alopecia in our two patients appears to be coincidental.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/6. acrodermatitis enteropathica--a case report.acrodermatitis enteropathica is a rare disease affecting infant girls. The skin in these cases develop rashes which start as vesicles and then dries to form erythematous squamous psoriasiform type of lesions. Dystrophy of nails and alopecia with loss of eye lashes and eye brows is also seen. Low serum zinc level is found in these patients and is thought to be the cause of this disease.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/6. Inherited progressive cone--rod dystrophy and alopecia.Two young sisters of Yemenite Jewish family with progressive cone-rod dystrophy accompanied with progressive alopecia of the scalp in one patient and with alopecia of the scalp and eyelashes in the other patient are presented. This rare disease seems to be autosomal recessively inherited since the patient's parents are first cousins and the family history is positive for a paternal grandmother and great-aunt having the same condition.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
5/6. Aplasia cutis congenita. A follow-up evaluation after 25 years.Aplasia cutis congenita is a rare disease with less than 300 cases reported in the literature. A patient with extensive involvement of the skin was observed for 25 years. During adolescence, a reactive depression related to the residual cicatricial alopecia on the left side of the scalp developed. The psychiatric distress disappeared after corrective surgery was performed. It is recommended that patients with this disorder be regularly observed to select cases appropriate for early plastic surgery.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
6/6. Intravenous gammaglobulin therapy of Satoyoshi syndrome.Satoyoshi syndrome is a very rare disease of unknown etiology, characterized by intermittent painful muscle spasms, alopecia, multiple epiphyseal changes, diarrhea and endocrine disorders. We administered intravenous gammaglobulin to a 7-year-old girl with Satoyoshi syndrome. Frequency of muscle spasms and the titers of antinuclear antibody and anti-dna antibody decreased. This is the first report of gammaglobulin therapy of Satoyoshi syndrome. We suggest that this illness could be related to an autoimmune mechanism.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |