1/7. Postoperative pressure-induced alopecia: report of a case and discussion of the role of apoptosis in non-scarring alopecia.We report a case of postoperative pressure induced alopecia in a 21-year-old black female after multiple intraoperative procedures. The histopathology is distinctive and demonstrated features in common with trichotillomania and alopecia areata, including the presence of pigment casts, catagen follicles, melanophages and apoptotic bodies. External hair manipulation is considered the primary event in the etiology of pigment casts, however, our present case demonstrated numerous pigment casts despite a complete lack of evidence of external hair manipulation. We performed pattern analysis and in situ end-labeling in 19 cases of non-scarring alopecia. Pigment casts were seen in postoperative alopecia (1 case), alopecia areata (1 case) and trichotillomania (5 cases). These forms of alopecia have in common the sudden termination of the anagen phase of the hair cycle. When the anagen portion of the hair cycle is prematurely disrupted hairs enter into catagen. Pigment casts may represent a non-specific reaction pattern of follicles that are suddenly transformed from anagen to catagen. We therefore propose that hair manipulation is not uniquely responsible for the formation of pigment casts. The primary pathophysiology resulting in the formation of pigment casts more correctly reflects the sudden termination of the anagen phase of the hair cycle.- - - - - - - - - - ranking = 1keywords = trichotillomania (Clic here for more details about this article) |
2/7. trichotillomania.trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance clinic and they all showed improvement with behavior therapy. A close liasion between the dermatologist, psychiatrist and parents would go a long way in preventing this alopecia- - - - - - - - - - ranking = 0.5keywords = trichotillomania (Clic here for more details about this article) |
3/7. Ant-induced alopecia: report of 2 cases and review of the literature.Localized scalp hair loss is associated with many processes, including alopecia areata, trichotillomania, tinea capitis, and early lupus erythematosus. There are several reports of localized alopecia after tick- and flea-bites and bee stings, but there are only two reports of ant-induced alopecia in the literature. We present two cases of alopecia induced by ants of genus Pheidole (species pallidula) and review the literature for insect-induced alopecia. Ant-induced alopecia should be considered in the differential diagnosis of localized sudden-onset alopecia, at least in some geographic areas of the world.- - - - - - - - - - ranking = 0.5keywords = trichotillomania (Clic here for more details about this article) |
4/7. trichotillomania associated with alopecia areata.An 18-year-old woman had alopecia areata of two years' duration. Initially, the clinical findings were quite characteristic of alopecia areata; however, the hair that grew back into the areas of alopecia remained short and sparse. Histopathologic examination suggested trichotillomania, which was confirmed by shaving a small area on the scalp and observing normal hair regrowth.- - - - - - - - - - ranking = 0.5keywords = trichotillomania (Clic here for more details about this article) |
5/7. Diagnostic value of exclamation mark hairs.Exclamation mark (EM) hair can lead to the misdiagnosis of alopecia areata (AA) because it is widely considered as pathognomonic for AA. Typical EM hairs were also found in trichotillomania. EM hairs collected from 2 cases of trichotillomania and 9 cases of AA were compared under light microscopy. There were two sorts of EM hairs, one with frayed distal ends and the other with blunt distal ends. The majority (77.8%) of the EM hairs from AA had frayed distal ends, while the majority (82.2%) of that from trichotillomania had blunt distal ends. EM hairs, even with frayed distal ends, are not pathognomonic of AA.- - - - - - - - - - ranking = 1.5keywords = trichotillomania (Clic here for more details about this article) |
6/7. trichotillomania in connection with alopecia areata.alopecia areata and trichotillomania present the most frequent causes of circumscribed hair loss in children. The connection between trichotillomania and alopecia areata has confused former observers. It may result from scratching at the site of alopecia areata that is symptomatic with pruritus, initiating a habit-forming behavior, or patients with a mental predisposition may artificially prolong the disfigurement as the hair on the bald patches of alopecia areata regrows. We have seen the concomitant occurrence of trichotillomania and alopecia areata in a 13-year-old boy, and confirmed the diagnosis by results of histopathologic examination. With regard to pathogenesis and prognosis, the differentiation of trichotillomania in connection with alopecia areata from the more common patterns of temporary localized childhood trichotillomania and severe adult trichotillomania is suggested.- - - - - - - - - - ranking = 3keywords = trichotillomania (Clic here for more details about this article) |
7/7. pachyonychia congenita-associated alopecia. A microscopic analysis using transverse section technique.pachyonychia congenita (PC) is a rare genodermatosis with characteristic nail abnormalities and occasional palmoplantar keratoderma and leukokeratosis oris; alopecia may occur (10% of patients). This report is the first microscopic description of a patient with PC-associated alopecia. Transverse section histologic features include diminished follicular density with preservation of follicular units, prominent miniaturization of follicles, dyskeratosis of outer root sheath keratinocytes, and moderate parakeratotic and orthokeratotic follicular hyperkeratosis. These microscopic features may be seen individually in other nonscarring alopecias, but the combination may be unique to PC-associated alopecia. Differential diagnoses include alopecia areata, androgenetic alopecia and traction alopecia/ trichotillomania.- - - - - - - - - - ranking = 0.5keywords = trichotillomania (Clic here for more details about this article) |