Cases reported "Anthrax"

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1/6. GI anthrax: report of one case confirmed with autopsy.

    BACKGROUND: Bacillus Anthraces is a non-motile, rod like, gram-positive and aerobic bacillus that produces central oval-shaped spores and characterized by rough, irregular and often comma-shaped colonies in blood agar. About 95% of human anthrax is cutaneous and 5% respiratory. GI anthrax, a very rare type, has been reported in less than 1% of all cases. We thus report a case of GI anthrax with autopsy findings. CASE REPORT: A 15-year-old young adult man was admitted to our hospital with history of fever, abdominal pain and bloody diarrhea from 48 hours after ingestion of half-cooked sheep's meat. In endoscopic exam of upper GI tract, the esophagus had been filled with fresh blood without any varices, stomach showed evidence of hemorrhage and had multiple erosion but no ulceration of duodenum. penicillin g 24,000,000 U/day IV was started but unfortunately severe upper and lower GI hemorrhage developed, leading to hypotension and death. In autopsy, ascites, paraaortic and mesenteric lymphadenopathy was accident with some of them being hemorrhagic. The spleen was slightly enlarged with hemorrhagic congestion in some parts of it. In the blood sample drawn from the spleen, the filamentous bacillus was successfully found. CONCLUSIONS: Because of the fatal nature of the disease and the similarity of the signs and symptoms to the other gastrointestinal diseases, we should consider it as one of the probable differential diagnosis in the patients with upper and lower gastrointestinal bleeding with fever esp. in the endemic areas.
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2/6. anthrax of the eyelids.

    anthrax is a disease caused by bacillus anthracis. The disease affects primarily herbivores including sheep, cattle, horses, and other domestic animals. humans may rarely be affected. We examined one male and two female patients with a localised itchy erythematous papule of the eyelid. A necrotising ulcer formed in each of the three cases resulting in a black lesion. Scraping in each case showed Gram positive rods and culture grew bacillus anthracis. All three patients responded to the intravenous administration of penicillin g, and the lesion resolved leaving scars in two cases. anthrax is a rare disease but should be considered in the differential diagnosis of ulcers or pustules of the eyelids.
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3/6. Three rare cases of anthrax arising from the same source.

    anthrax is an acute bacterial infection caused by bacillus anthracis. humans become infected under natural conditions by contact with infected animals or contaminated animal products. About 95% of human anthrax is cutaneous and 5% respiratory. Gastrointestinal anthrax is very rare, and has been reported in less than 1% of all cases. anthrax meningitis is a rare complication of any of the other three forms of disease. We report three rare cases of anthrax (gastrointestinal, oropharyngeal and meningitis) arising from the same source. The three patients were from a single family and were admitted with different clinical pictures after the ingestion of half-cooked meat from a sick sheep. These cases emphasize the need for awareness of anthrax in the differential diagnosis in areas where the disease remains endemic.
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4/6. An outbreak of anthrax meningoencephalitis.

    We report a common-source outbreak of anthrax meningoencephalitis in Chittoor district in Andhra Pradesh, southern india, in October 1990. The source of infection was the carcass of a sheep. Of 5 persons who skinned and cut up its meat for human consumption, 4 developed anthrax meningoencephalitis and one a malignant pustule. Another person who wrapped the meat in a cloth and carried it home on his head developed a malignant pustule on his forehead and also meningoencephalitis. All subjects with anthrax meningoencephalitis died, but the one with only a malignant pustule recovered. A large number of people who cooked or ate the cooked meat of the dead sheep remained well. The medical, public health and veterinary authorities were alerted and sheep, goats and cattle in the locality were immunized with anthrax vaccine. Although rules against consumption of meat of dead animals exist, their violation shows a lack of public awareness. health education should be undertaken to correct this situation.
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5/6. Indigenous human cutaneous anthrax in texas.

    In December 1988 an indigenous case of cutaneous anthrax was identified in texas. The patient, a 63-year-old male Hispanic from southwest texas, was a sheep shearer and had a recent history of dissecting sheep that had died suddenly. He experienced an illness characterized by left arm pain and edema. A necrotic lesion developed on his left forearm, with cellulitis and lymphadenopathy. After treatment with oral and intravenous penicillins, the patient fully recovered. Western blot testing revealed a fourfold or greater rise in antibody titer to bacillus anthracis protective antigen and lethal factor. This represents the first case of indigenous anthrax in texas in more than 20 years.
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6/6. anthrax as the cause of preseptal cellulitis.

    anthrax is an infectious disease caused by bacillus anthracis. It is primarily a disease of domestic animals such as cattle, goats, and sheep; but humans can rarely be infected by contact with infected animals or contaminated animal products. Our case is a 4-year-old boy who was initially diagnosed as preseptal cellulitis, but later he showed the characteristic anthrax lesions with a black necrotic eschar. Scrapings from the necrotic tissue showed gram positive rods and culture grew bacillus anthracis. The patient responded to intravenous administration of penicillin g, and the lesions resolved, leaving a scar on the right upper eyelid. Eyelid involvement of anthrax is rarely seen in clinical practice, but should be considered in differential diagnosis.
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