1/4. Interstitial granulomatous dermatitis with plaques and arthritis.Interstitial granulomatous dermatitis and arthritis (IGDA) is a rare disease entity with female predominance. The case of a 53-year-old woman with erythemas, plaques and nodules associated with polyarthritis is presented. She was treated with cyclosporin A, with improvement of the joint affliction and complete clearance of skin lesions. The differential diagnosis of IGDA is discussed briefly.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/4. A case of hereditary angioedema with recurrent arthritis, erythema marginatum-like rash and chest pain.Hereditary angioedema (HAE) results from a congenital deficiency of C1 inhibitor and is characterized by submucosal and subcutaneous edema of skin, larynx and abdomen. Occasional reports have appeared linking HAE with autoimmune diseases. We report a case of HAE presenting recurrent nondeforming polyarthritis, erythema marginatum-like rash and chest pain. There were no significant radiographic joint changes. serologic tests for rheumatologic and autoimmune diseases were negative. After danazol treatment, physical examination and laboratory findings were normal over five years. We suggest that pediatricians should be aware of this rare disease and treat patients accordingly.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/4. adult-onset acute rheumatic fever: possible resurgence in southern taiwan.BACKGROUND: By the late 1980s, acute rheumatic fever (ARF) had become a rare disease in taiwan. The low prevalence rate in this area is attributed to a better economic status, which has led to improved public health and adequate medical services. OBJECTIVES: The increasing number of patients with adult-onset ARF in the united states described in the literature prompted us to evaluate the cases diagnosed in our medical center. methods: A retrospective chart review was performed for patients with arthritis from July 1988 to October 2004. To be included, patients had to meet revised Jones criteria. RESULTS: Three adult patients with ARF have been diagnosed since June 2001, with no childhood ARF being diagnosed. All cases presented with migratory polyarthritis, whereas 1 had erythema marginatum and transient carditis. These patients responded well to treatment with antibiotics and nonsteroidal antiinflammatory drugs. CONCLUSIONS: Clinicians must provide careful assessment and treatment to patients presenting with acute pharyngitis. A possible resurgence of ARF can be eradicated by primary prevention of streptococcal pharyngitis.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/4. melkersson-rosenthal syndrome in a patient with sero-negative oligoarthritis.The melkersson-rosenthal syndrome is a rare disease consisting of orofacial swellings, facial nerve palsy and plicated tongue. The etiology is unknown. On histopathological examination a characteristic granulomatous inflammation is found. A case of this syndrome in a young white female with seronegative oligoarthritis is described and the possible relationship between the two diseases is discussed on the basis of the literature.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |