1/13. carcinoid tumor of the cystic duct.A 69-year-old male was admitted to an outside institution for severe right abdominal pain radiating to the flank. An extensive work-up, including lower GI series, IVP, and ultrasound of the kidneys were normal. Ultrasound of the liver demonstrated a thickened gallbladder as well as cholelithiasis. Despite some improvement, his symptoms returned intermittently and cholecystectomy was performed. Pathologic examination of the gallbladder showed a carcinoid tumor, 5.4 mm in maximum diameter, in the cystic duct. A small metastatic focus was also found in the cystic duct lymph node. In this paper we compare the clinical presentation, pathological findings and outcome of this case to the previously reported six cases of cystic duct carcinoid. A comparison is also made between the general features of carcinoid at this rare location and the more common gastrointestinal carcinoid.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
2/13. Synchronous carcinoma of the gallbladder in a patient with intrahepatic bile duct carcinoma.An 83-year-old woman, diagnosed as having cholelithiasis, was admitted to the Department of Surgery, Nippon Medical School, with right hypochondrial pain. ultrasonography and computed tomography revealed a mass in the gallbladder fundus and a hypovascular tumor in the anterior segment of the liver. magnetic resonance imaging showed stenosis of the intrahepatic bile duct and dilatation of its proximal portion. She was diagnosed as having intrahepatic bile duct carcinoma combined with gallbladder carcinoma. At laparotomy, there was evidence of multiple peritoneal metastases and intraoperative histological examination of the gallbladder tumor revealed adenocarcinoma. Accordingly, only cholecystectomy and needle biopsy of the liver tumor was performed. Histological examination of the gallbladder revealed papillary adenocarcinoma invading the muscularis propria with medullary growth or intermediate stroma. There was no microvessel invasion, no perineural invasion and no lymph node involvement. On the other hand, the liver tumor was a cholangiocarcinoma with a well-differentiated tubular pattern. Therefore, this was a rare case of synchronous carcinoma of the gallbladder associated with intrahepatic bile duct carcinoma.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
3/13. Giant cell tumor-like cholangiocarcinoma associated with systemic cholelithiasis.A cholangiocarcinoma of the hepatic hilus with an element of giant cell tumor that occurred in a 59-year-old man is reported. His medical history included systemic cholelithiasis and repeated operations on the biliary passages. Four years after the last operation, which was a hepatic segmentectomy, he was readmitted because of persistent fever. A computed tomography scan showed a low-density area and stones in the hepatic hilus. He died of hepatic failure approximately 1 month later. At autopsy, a fist-sized tumor and gallstones were found at the hepatic hilus. Histologically, the tumor mainly showed sarcomatoid features and some tubular adenocarcinoma. An element of giant cell tumor consisting of many osteoclast-type giant cells also was noted. The results of immunohistochemical studies showed a positive reaction to cytokeratin and vimentin in some of the spindle-shaped sarcomatoid cells. Sarcomatoid bile duct carcinomas are rare, as are those with osteoclast-type giant cells. The authors also discuss the histogenesis of these giant cells.- - - - - - - - - - ranking = 5keywords = cholelithiasis (Clic here for more details about this article) |
4/13. Eosinophilic cholangitis: a self-limited cause of extrahepatic biliary obstruction.The first case of eosinophilic cholecystitis with radiographically documented biliary tract obstruction is presented. Differences between eosinophilic cholecystitis with and without obstruction in terms of gender predilection and the incidence of associated cholelithiasis suggest these may be two distinct disease processes. The dense eosinophilic infiltration of the porta hepatis seen in the present case has led us to believe that extrahepatic obstruction was due to "eosinophilic cholangitis." The self-limited nature of eosinophilic cholangitis makes it an essential consideration in the evaluation of presumed neoplasms of the porta hepatis.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
5/13. Hepatocellular carcinoma presenting extrahepatic obstructive jaundice due to bile duct invasion--clinicopathological study of two cases.Two rare cases of autopsy and surgery presenting extrahepatic biliary obstruction due to intrabile-duct growth of hepatocellular carcinoma were reported. Clinically obstructive jaundice was predominant in comparison with the other symptoms in both cases. In one autopsy case, hepatocellular carcinoma developed in the right lobe of the cirrhotic liver (posthepatitic). It involved the secondary branch of the right hepatic duct and grew into the common hepatic duct. In the other case of surgical operation, hepatocellular carcinoma, which developed in the posterior portion of the right lobe of the cirrhotic liver (posthepatitic), destroyed the posterior wall of the bifurcation of the bilateral hepatic duct and obstructed the common hepatic duct due to the intraductal cancer growth. From the site of the bile duct invasion or permeation by the tumor, two cases were classified into the peripheral (the former case) and proximal (the latter case) types, respectively. Furthermore, as far as obstructive jaundice is clinically concerned, the possibility should be kept in mind that hepatocellular carcinoma may proliferate into the large bile ducts, apart from that of cholangiocarcinoma or cholelithiasis.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
6/13. Pancreatic enzyme levels in bile of patients with extrahepatic biliary tract disease.A total of ninety three patients with biliary tract disease were studied to determine the concentration of the pancreatic enzymes, amylase and lipase, in bile obtained from the gallbladder and/or common bile duct. Of seventy gallbladder bile samples, amylase levels were higher than actual or predicted serum levels in 87 per cent, while bile lipase were higher than serum lipase values in 66 per cent. Bile obtained from the common bile duct had enzyme concentrations which fluctuated from values similar to those in serum to remarkably high levels. This suggests that pancreatic enzymes enter the biliary system through a common terminal ampulla which is known to exist in 60 to 90 per cent of human subjects. The premise is advanced that pancreatic enzymes may initiate inflammatory changes in the gallbladder and could play a role in gallstone formation by altering the constituents which maintain cholesterol in a soluble state. Biliary reflux of pancreatic enzymes could play a role in the pathogenesis of some cases of cholecystitis can cholelithiasis.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
7/13. Heterotopic duodenum in the cystic duct.Duodenal tissue was an incidental microscopic finding in a gallbladder that was removed for an acute and chronic cholecystitis with cholelithiasis and choledocholithiasis. To my knowledge, no other case of duodenal heterotopia in the cystic duct or gallbladder has been reported in the literature.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
8/13. Asbestos bodies in a bile duct cancer after occupational exposure.A case of asbestosis after 5 years of occupational asbestos exposure is presented. At the postmortem examination, cholelithiasis and a cancer developing from the cystic duct were found and identified histologically as a squamous cell carcinoma. After digesting the tumor tissue, short asbestos bodies and fragments could be identified having a similar shape as those observed in the lung. The possible role of asbestos in the carcinogenesis of the observed bile duct cancer is proposed. The digestive examination of all malignant tumors of any origin after an asbestos exposure is suggested for the identification of the possible presence of ingested asbestos fibers, and to obtain further comprehensive human pathological data.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
9/13. Granular cell schwannoma of the extrahepatic biliary system.We report the case of a woman who presented with a typical picture of cholelithiasis and choledocholithiasis. A percutaneous transhepatic cholangiogram revealed instead a concentric narrowing of the common bile duct and at operation she was found to have a rare, benign tumor of the extrahepatic biliary tree, a granular cell schwannoma.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
10/13. Case report: granular cell tumour of the biliary tree--the sonographic appearance.A case of granular cell tumour (GCT) of the biliary tree is reported with the first published sonographic images of this tumour. The difficulty in distinguishing this tumour from cholelithiasis is illustrated.- - - - - - - - - - ranking = 1keywords = cholelithiasis (Clic here for more details about this article) |
| | Next -> |