1/30. lobomycosis. Report of the eighth Colombian case and review of the literature.The eighth Colombian case of lobomycosis and the one hundredth in the world literature is reported here. The patient was a 38-year-old female who showed a bilobed mass on the left forearm which had appeared at the site from where a similar lesion had been excised 19 years previously. She had always lived in a rural area, located in the humid subtropical forest. The tissue reactions to the fungus as well as the fruitless attempts to culture it are described. An analysis of the relevant literature is made and suggestions for experimental animal models are given in the text.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
2/30. Isolation of blastomyces dermatitidis from pigeon manure.We recently diagnosed and treated a 45-year-old white male horticulturist with acute progressive blastomycosis. epidemiologic studies revealed that the patient used a load of pigeon manure as fertilizer approximately 6 weeks before becoming ill. He used the pigeon manure only once, resealed the remainder, and stored it in his hothouse. Samples of the pigeon guano were digested with 10 per cent KOH, and the characteristic yeast forms of blastomyces dermatitidis were seen in large numbers. The fungus was cultured from another sample of the same material. This is the first time that the pathogenic fungus B. dermatitidis has been isolated from the environment in association with a human case.- - - - - - - - - - ranking = 2keywords = fungus (Clic here for more details about this article) |
3/30. Expanding epidemiology of blastomycosis: clinical features and investigation of 2 cases in colorado.On the basis of case reports of blastomycosis, blastomyces dermatitidis is widely accepted to be endemic in the central United States in and around the ohio and mississippi River Valleys. blastomycosis also occurs in parts of canada and in the southeastern united states. However, there has been no large-scale skin testing, and the environmental range of B. dermatitidis may have been underestimated. We describe 2 immunocompetent patients with blastomycosis acquired while working in the Front Range region of the Rocky Mountains. The patients were coworkers engaged in a prairie dog relocation project. In the course of this work, they had extensive contact with contaminated soil. Significantly above-average rainfall before the exposure may have contributed to favorable conditions for sporulation of the fungus.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
4/30. Tropical mycoses.The most common tropical subcutaneous and deep mycoses include chromomycosis, sporotrichosis and mycetoma. All are commonly found in Natal and in other subtropical countries. Although blastomycosis is endemic in north america, only 4 cases have been identified in Natal during the last 25 years, and all presented with atypical clinical features. African histoplasmosis, caused by histoplasma capsulatum var. duboisii and limited mainly to central and western Africa, has been found in only 1 patient in Natal. paracoccidioidomycosis, though the most common deep mycosis in latin america, is limited to that area and there is no experience of this disease in south africa. Over the past 8 years, itraconazole has been used in clinical trials for all 3 mycoses. The results in sporotrichosis, non-meningeal blastomycosis and paracoccidioidomycosis suggest that for these diseases itraconazole may be the drug of choice. The results in histoplasmosis are encouraging, as are the results in chromomycosis, particularly those cases associated with cladosporium carrionii. Where Fonsecaea pedrosoi is the causal agent and in mycetomas, however, successful management still remains a therapeutic problem. Enhanced efficacy by combining flucytosine and itraconazole was seen in 3 patients. Even over prolonged periods, itraconazole has an impressive safety profile. In the present series of 41 patients, no side-effects were observed, no adverse reactions occurred, and serum chemistry values remained within normal limits. It appears, therefore, that itraconazole, though not the final answer to management of deep mycoses, is certainly a major improvement on previous drugs.- - - - - - - - - - ranking = 53.489108128949keywords = mycoses (Clic here for more details about this article) |
5/30. blastomycosis: a reminder of kentucky's other fungus.Although not as common as histoplasmosis, the disease caused by blastomyces dermatitidis is also endemic in the Commonwealth of kentucky. Greater clinical awareness of this systemic mycosis and the newer effective forms of treatment may lessen the significant morbidity and mortality of this potentially serious infection. To illustrate the varied manifestations of this illness, we contrast the presentation of an urban female with blastomycosis and atypical chest radiographic changes to the more classic features of blastomycosis described in the literature.- - - - - - - - - - ranking = 4keywords = fungus (Clic here for more details about this article) |
6/30. Disseminated blastomycosis in an infant.blastomycosis is an uncommon life-threatening disease caused by the dimorphic fungus blastomyces dermatitidis. Estimates of the percentage of cases occurring in children range from 2% to 11%, and it is exceedingly rare in individuals less than 1 year of age. We present the case of an otherwise healthy infant with disseminated blastomycosis acquired in Northern ontario and a brief review of the pediatric literature.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
7/30. blastomycosis presenting as recurrent tender cutaneous nodules.blastomycosis is caused by inhalation of airborne spores from blastomyces dermatitidis, a dimorphic fungus found in soil. It is endemic in the southeastern, Midwestern, and south central states of north america. The clinical spectrum of blastomycosis is varied, including asymptomatic infection, acute or chronic pneumonia, and disseminated disease. Definitive diagnosis is based on identification of the characteristic thick-walled, broad-based budding yeasts by direct examination of tissue or the isolation of blastomyces in culture. itraconazole is the treatment of choice for mild to moderate pulmonary disease. amphotericin b is the first line agent in life-threatening disseminated disease, central nervous system involvement, acute respiratory distress syndrome, pregnancy, immunocompromised states, and in those who cannot tolerate or fail azole therapy. We report a case of blastomycosis presenting as a fever of unknown etiology and recurrent skin nodules.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
8/30. blastomycosis in a South Indian patient after visiting an endemic area in USA.We describe a case of blastomycosis in a diabetic patient from South india who had visited Milwaukee, wisconsin, an endemic area for blastomycosis in the USA. After his return to Bangalore, india, the patient developed intermittent fever of moderate to high grade, cough, loss of weight and appetite, and abscesses in the left cubital fossa and thigh regions. Systemic examination at our hospital revealed that he had dullness to percussion over the chest region and decreased breath sounds. Direct examination of Gram-stained smears of the pus from an abscess showed many broad-based budding yeast cells and culture yielded a dimorphic fungus later identified as blastomyces dermatitidis. Histologic examination of the curettage tissue slides stained with hematoxylin and eosin, periodic acid Schiff's reagent, and Gomori's methenamine silver stain procedures showed many broad-based budding cells characteristic of B. dermatitidis. The patient was successfully treated, initially with amphotericin b, followed by oral itraconazole for a period of 6 months. blastomycosis cases in india are reviewed and the likely source of infection in this patient is discussed.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
9/30. Northern wisconsin married couple infected with blastomycosis.blastomycosis is an uncommon, chronic, granulomatous disease caused by the dimorphic fungus blastomycosis dermatitidis. The great majority of infections start with primary pulmonary involvement through inhalation of spores. Hematogenous dissemination to other sites occurs in 25% to 30% of cases. The most common secondary site is the skin, followed in order by bone, genitourinary system, and central venous system. We report 2 cases of blastomycosis originating in a husband and wife who were both symptomatic and diagnosed with blastomycosis within 4 months of each other. One presented with pulmonary symptoms, the other with cutaneous symptoms. These 2 cases of husband and wife are of interest not only because of their rarity but also because of the potential mode of transmission.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
10/30. Exfoliative cytology in the rapid diagnosis of pulmonary blastomycosis.Four patients with pulmonary blastomycosis are reported. Their bronchial washings, submitted for cytologic evaluation and stained by the standard Papanicolau technique, yielded the diagnosis, subsequently confirmed by cultural identification of the fungus. In three additional cases, retrospective evaluation of cytologic material also revealed the organism, even though the diagnostic significance was not appreciated originally. Since cytologic techniques are simple, readily available, and rapid, they can be helpful in differentiating pulmonary neoplasms from pulmonary blastomycosis, thus reducing the need for diagnostic thoracotomies.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
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