1/6. Idiopathic diabetic bullosum. A case report.The authors describe a case in which an 88-year-old black male with a long-standing history of diabetes, blindness, and dialysis therapy presented with idiopathic diabetic bullosum of the left foot distal extremities. The lesions usually are intraepidermal and resolve spontaneously over a period of weeks with no resulting scar formation. The lesions are highly recurrent. In this specific case, the long healing time may be attributed to the age of the patient as well as the decrease in immune and systemic response to injury, weakened by dialysis therapy and his poor arterial status.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
2/6. Intermediate alpha 1-antitrypsin deficiency with apical lung bullae and spontaneous pneumothorax. Presence of a Z variant in an American black.A 43-year-old black man had an 18-year history of apical lung cystic-bullous disease. Following two episodes of spontaneous pneumothorax and two instances of thoracotomy for bullectomy and pleural abrasion, he was found to have an intermediate AAT deficiency with an MZ phenotype. It is believed that this is the first case of localized bullous lung disease to be reported in association with any degree of AAT deficiency. There is evidence that the cystic lesions progressed to form upper lobe bullae. It is postulated that the AAT deficiency may have played a role in this progression, as did the patient's cigarette smoking. Following two instances of surgery, CT scans of the lungs, compliance studies and complete pulmonary function tests show no further evidence of lung bullae or emphysema. The rarity of the Z variant of AAT in blacks is discussed.- - - - - - - - - - ranking = 6keywords = black (Clic here for more details about this article) |
3/6. A cluster of blister-associated toxic shock syndrome in male military trainees and a study of staphylococcal carriage patterns.In March-April 1985, toxic shock syndrome (TSS) developed in three male military trainees at one base secondary to infected blisters acquired while marching during basic combat training. One trainee died. staphylococcus aureus was isolated from the blisters in all three patients, and the two strains available for testing both produced toxic shock syndrome toxin-1 (TSST-1). A culture survey identified carriage of S. aureus in 44% (145/333) of the trainees; carriage rates did not differ between the company with two ill trainees and a control company. Carriage was more frequent in the nose than foot (41% versus 9%, p less than 0.0001). White trainees were more likely to carry S. aureus than black trainees (47% versus 28%, p = 0.013), although the same proportion of strains was positive for TSST-1 in both races. The two strains obtained from the patients had similar but not identical phage typing patterns, but had identical antibiograms, and neither strain carried any plasmids. Based upon phage typing of the TSST-1 positive S. aureus strains isolated in the study, widespread carriage of the case strain(s) in other trainees was not found nor was clustering noted by barrack room. It is possible that differences in carriage rates may partially explain the low rate of TSS in blacks.- - - - - - - - - - ranking = 2keywords = black (Clic here for more details about this article) |
4/6. cryotherapy improves prurigo nodularis.A 55-year-old black woman with an eight-year history of prurigo nodularis was treated successfully with blistering cryotherapy. cryotherapy resulted in smooth macule formation and afforded extended relief of pruritus. Several standard modalities of treatment had been used previously and had resulted in only partial relief of symptoms and minimal reduction of nodule size. This case demonstrates that cryotherapy can be a useful therapeutic alternative for prurigo nodularis.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
5/6. Infantile acropustulosis.Infantile acropustulosis (IA) is a syndrome characterized by recurrent crops of 1- to 2-mm intensely pruritic vesicopustules that are found primarily on the distal extremities of infants. It is reportedly responsive to sulfones and unresponsive to other therapy, but if left untreated spontaneously resolves at about 2 years of age. It is more common in black male patients. The histopathologic findings and clinical course are distinct.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
6/6. Three cases of idiopathic interstitial pneumonia with bullae seen in schoolteachers.We encountered three patients with chronic interstitial pneumonia with many bullae in the lower lung fields whose lifetime occupation was teaching school. Pathological examination of autopsy lungs of these patients revealed interstitial pneumonia and multiple bullae throughout the lungs, including the lower lobe. Since blackboard chalk has been used as a popular writing material among teachers in japan, the mineral contents in the lungs of two of the three cases and four control cases with idiopathic interstitial pneumonia (IIP) (whose occupations were not teaching) were analyzed. The amount of deposition of total dust, inorganic dust, non-SiO2 inorganic dust, and calcium was significantly higher in the lungs of two schoolteachers compared with those of the control lungs. The amount of free silica in case 1 and alpha-quartz in case 3 were also significantly higher than in the controls. Two thirds of the chalk produced in japan is still made from gypsum and involves small amounts of silica and other minerals, in addition to calcium. These findings indicated the deposition of chalk in the lungs of these patients with interstitial pneumonia and multiple bullae.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |