Cases reported "Bone Neoplasms"

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1/66. Conservative surgery for chondrosarcoma of the first metacarpal bone.

    A rare case of a chondrosarcoma of the first metacarpal bone is presented. The lesion was radiographically interpreted initially as an enchondroma and treated conventionally by curettage and cancellous autologous bone grafting. After final histology, a low-grade chondrosarcoma was reported. A resection of the entire first metacarpal bone was performed, followed by reconstruction using an autologous corticocancellous bone graft and plate fixation, creating arthrodeses of the adjacent joints. Although isolated enchondromas are considered to have no malignant potential, histological examination is essential to rule out malignancy. A preoperative biopsy should be recommended in lesions suspected to be chondromas. Chondrosarcomas are rarely located in bones of the hand, where they are usually treated by amputation. With the case presented we wish to advocate that cases of low-grade, intraosseous chondrosarcoma (stage IA) can be treated by conservative surgery, especially when it is located in the thumb.
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ranking = 1
keywords = enchondroma
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2/66. Chondromyxoid fibroma of the acromium with soft tissue extension.

    Chondromyxoid fibroma is an unusual, benign tumor of cartilaginous origin and represents less than 1% of all primary bone tumors. It usually involves the long bones around the knee joint or the flat bones of the pelvis or ribs. Soft tissue extension is also thought to be rare in these lesions. They are usually eccentrically located in the metaphyses of the long bones and centrally in the flat bones. The radiographic appearances are characteristically those of a single, lytic lesion with lobulated margins, septations, cortical expansion and a sclerotic rim. Histologically, they display a lobulated pattern with spindle-shaped cells lying within a myxoid matrix with areas of hyaline cartilage. The differential diagnosis includes giant cell tumor, chondroblastoma or enchondroma as well as chondrosarcoma. The rarity of these lesions may render the diagnosis difficult to make, especially when the lesion involves an unusual site such as the acromium.
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ranking = 0.5
keywords = enchondroma
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3/66. coccidioidomycosis fungal infection in the hand mimicking a metacarpal enchondroma.

    coccidioidomycosis, an infection caused by the fungus coccidioides immitis, rarely affects the hand, but we report an unusual case which mimicked the radiological appearance of an enchondroma in the metacarpal. curettage and bone grafting in combination with long-term antifungal therapy are necessary for successful treatment of coccidioidomycosis of the hand.
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ranking = 2.5
keywords = enchondroma
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4/66. chondrosarcoma of the distal phalanx of a toe. A case report.

    Secondary malignant transformation of a solitary enchondroma into a chondrosarcoma is extremely rare. We report a case of such transformation in anenchondroma of the distal phalanx of a toe.
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ranking = 1
keywords = enchondroma
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5/66. Low-grade chondrosarcoma vs enchondroma: challenges in diagnosis and management.

    A 28-year-old man presented with a swelling at the right thoracic wall. Computed tomography showed an aggressive process involving the cortex of the rib with concomitant soft tissue mass. However, a needle biopsy specimen revealed an enchondroma and consequently the physician decided to apply a "wait-and-see" strategy. After 3 years of careful follow-up by MR imaging, the patient complained of subtle enlargement of the lesion, which was later confirmed on repeated CT scan. Despite an aggressive appearance on control MR imaging, histopathological examination after incisional biopsy could not differentiate between enchondroma and low-grade chondrosarcoma. Wide excision including previous biopsy trajectory was performed. diagnosis of a low-grade (grade I) chondrosarcoma was made on findings of the excisional specimen and seeding of cartilage tissue along the previous incisional biopsy trajectory was found.
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ranking = 3
keywords = enchondroma
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6/66. A jammed finger from basketball.

    A benign enchondroma of the left fifth distal interphalangeal joint occurred in a 39 year old male. The differential diagnoses and outcomes are discussed.
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ranking = 0.5
keywords = enchondroma
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7/66. Flexor digitorum profundus tendon avulsion through a recurrent enchondroma--a case report.

    Flexor digitorum profundus (FDP) tendon avulsion from the distal phalanx is a well recognised injury, which usually follows a hyperextension force to a flexed distal interphalangeal (DIP) joint. It is commonly seen in contact sport athletes, with a predilection for the ring finger.(2,4) Avulsion of the FDP tendon from pathological bone is an infrequent occurrence. It has, however, been reported to occur in association with an enchondroma of the distal phalanx.(2,3) To our knowledge, an FDP tendon avulsion through a recurrent enchondroma has not been reported. We present the case findings of such an event.
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ranking = 3
keywords = enchondroma
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8/66. chondrosarcoma of the hand arising from a pre-existent benign solitary enchondroma.

    Chondrosarcomas of the hand are relatively rare. Chondrosarcomas may arise by malignant transformation of a pre-existing enchondroma, but this causal relationship has been difficult to establish in solitary enchondroma. This is a case report of a chondrosarcoma of the proximal phalanx of the right index finger in a 66-year-old woman demonstrating histologic evidence of malignant transformation of a pre-existent benign solitaary enchondroma. Careful analysis of the preoperative X-ray for punctate endosteal calcification or cortical expansion and ample histologic sampling of the endosteal component of chondrosarcomas arising from within bone may demonstrate a greater incidence of preexistent enchondroma.
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ranking = 4
keywords = enchondroma
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9/66. First report of parotid gland metastasis in multiple enchondromatosis with secondary CHOSA (G-III).

    Chondrosarcomas constitute the second-most-frequent malignant bone tumors, representing about 10% of all malignant bone tumors. The most frequent localizations comprise the trunk, pelvis and limbs. Metastatic disease usually occurs in the lung; metastases to other localizations are seen occasionally. Manifestation in the head and neck area, either as primary tumor or metastasis, is very rare. A case of parotid gland metastasis in multiple enchondromatosis secondary chondrosarcoma (CHOSA) G-III of the left femoral bone is presented. A 79-year-old male patient reported to our clinic with a rapidly progressing mass in the left parotid gland. A superficial parotidectomy was performed and the entire tumor resected. Histopathological examination revealed nodular infiltration of the parotid by chondrosarcoma consistent with metastatic disease. review of the literature shows that this is the first report of such a case.
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ranking = 2.5844245599255
keywords = enchondroma, enchondromatosis
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10/66. Pathologic fracture of metacarpal enchondroma: case study and differential diagnosis.

    OBJECTIVE: To discuss a case of enchondroma initially appearing as a pathologic fracture in a metacarpal bone. The recommended treatment for a pathologic fracture of an enchondroma in the hand is reviewed. Additionally, a reasonable list of differential considerations is presented with accompanying radiographic and advanced imaging characteristics. CLINICAL FEATURES: A 25-year-old male chiropractic student had a painful, bruised, and swollen thumb following athletic trauma. Radiographs showed a pathologic comminuted fracture of the first metacarpal, with a resultant anterior angulation of the distal fragment. Fracture occurred through a well-defined, geographic, lucent lesion in the proximal metaphysis consistent with enchondroma. INTERVENTION AND OUTCOME: Closed reduction of the fracture and casting were used. No treatment was administered for the enchondroma. Adequate healing of the fracture took place with residual angulation at the fracture site. Size and extent of the enchondroma were unchanged after fracture healing. CONCLUSIONS: Recommended treatment for a pathologic fracture through an enchondroma in the hand is casting, which allows fracture healing. curettage of the lesion without packing of the resultant cavity is then recommended. In this case, casting and fracture healing took place without any treatment directed at the enchondroma. The patient was advised of the rationale for undergoing the removal of the enchondroma. Removal was recommended to prevent fracture recurrence from structural weakening, which would be likely due to the unusually high level of mechanical stress from the professional demands of manual treatment.
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ranking = 6
keywords = enchondroma
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