1/5. The presence of HPV types 6/11, 16/18, 31/33/51 in Bowenoid papulosis demonstrated by dna in situ hybridization.Bowenoid papulosis (BP) is an unusual dermatosis with variable clinical presentation: multiple, generally small, round, papules, isolated or confluent, with smooth or papillomatous surface, sometimes with desquamation. The colour is variable from rose, reddish-purple to brown. These papules are localized mostly on the genital mucosa or perigenital skin of young adults. The aetiopathogenesis of the disorder is not well defined, but it may be linked to human papillomavirus (HPV) infection. We report a case of BP with some particular aspects: (1) misdiagnosis of the disease for 2 years; (2) contemporaneous presence of different types of HPV.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
2/5. Bowen disease associated with porokeratosis of Mibelli.A 73-year-old woman developed Bowen precancerous dermatosis in an area of porokeratosis of Mibelli on her leg. This is the fourth reported case of Bowen disease arising from porokeratosis of Mibelli. The recent literature indicates that porokeratosis of Mibelli may be due to an abnormal clone of cells, predisposing affected individuals to development of malignant neoplasms over the involved areas.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
3/5. dermoscopy in epidermodysplasia verruciformis.BACKGROUND: epidermodysplasia verruciformis (EV) is a rare autosomal recessive genodermatosis characterized by an impairment of cellular immunity. It clinically manifests as widespread, long-lasting, pityriasis versicolor-like macules and flat, wart-like papules, usually occurring in early childhood. There is a risk of development of multiple skin cancers in the third decade, primarily in sun-exposed skin. EV-associated human papillomaviruses have been implicated in a number of cutaneous lesions in non-EV populations, such as seborrheic keratoses or psoriasis. They have also been implicated in the development of nonmelanoma skin cancer, especially in immunosuppressed patients. patients affected with EV are not able to eliminate oncogenic viruses within lesions, leading to a malignant transformation. OBJECTIVE: To describe the dermoscopic characteristics of EV cutaneous tumors by performing histopathologic correlation. methods AND MATERIALS: Cutaneous lesions and tumors from two patients affected by EV were included. Clinical and dermoscopic images were obtained and excision with ulterior histopathology was performed in all suspicious tumors and characteristic lesions. RESULTS: dermoscopy and histology of pityiriasis versicolor-like macules, wart-like papules, seborrheic keratosis-like tumors, psoriasis-like plaques, collision tumors, and Bowen in situ carcinoma are described. CONCLUSIONS: dermoscopy in EV tumors correlated with histopathologic findings and improved the differential diagnosis of tumors in this disease.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
4/5. small cell lung carcinoma and bowen's disease 40 years after arsenic ingestion.A non-smoking woman presented with ectopic ACTH syndrome associated with disseminated small cell carcinoma of lung. The patient had bowen's disease and had taken oral arsenic for psoriasis 40 years ago. It is postulated that the previous therapeutic arsenic ingestion caused both her arsenical dermatosis and her small cell carcinoma of lung.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
5/5. Bowenoid papulosis of the penis.Bowenoid papulosis of the penis is a recently emerged entity that clinically resembles benign dermatosis but it is histologically identical to pre-invasive carcinoma. Its lesions are multiple, painless and wart-like in appearance, and occur in young, circumcised men between 21 and 38 years old. Therapy consists of excision, electrodissection or topical 5-fluorouracil. We report 2 cases of bowenoid papulosis of the penis and compare this entity to bowen's disease, erythroplasia of Queyrat and invasive carcinoma.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |