1/236. breast cancer and hiv: what do we know?The present acquired human immunodeficiency syndrome-defining neoplasms are Kaposi's sarcoma, non-Hodgkins lymphoma, and cervical cancer. However, other malignancies have recently been associated with human immunodeficiency virus (hiv) infection. Is there also a link between breast cancer and hiv infection? breast cancer seems to be more aggressive in the setting of immunocompromise by hiv infection, as demonstrated by the clinical course of two patients recently treated at this institution and review of the available literature. As the acquired human immunodeficiency syndrome epidemic affects increasing numbers of women and survival improves, surgeons will be frequently called on to diagnose and treat breast cancer in the hiv patient.- - - - - - - - - - ranking = 1keywords = lymphoma (Clic here for more details about this article) |
2/236. Primary lymphoma of the breast: MR imaging features. A case report.Primary non-Hodgkin's lymphoma (NHL) of the breast are rare and represent less than 0.6% of all mammary malignancies. Secondary involvement of the breast in patients with diffuse disease occurs more frequently. The radiologic features of breast lymphoma are nonspecific, and the diagnosis is based on histologic criteria. We present the MR-imaging features of a case of primary NHL of the breast.- - - - - - - - - - ranking = 6keywords = lymphoma (Clic here for more details about this article) |
3/236. Myxoid variant of follicular dendritic cell sarcoma arising in the breast.Follicular dendritic cell sarcoma is a malignant tumor of the follicular dendritic cell which can arise in extranodal sites. We present here a case arising as a mass in the breast of a 41-year-old woman. The tumor was composed of mildly pleomorphic spindly cells with pale ovoid nuclei and cell processes intimately admixed with mature lymphocytes. In much of the lesion the cells were dispersed in cords in a myxoid stroma, and elsewhere there were solid sheets. The neoplastic cells were immunoreactive for CD21, CD35, EMA, and S100 protein, but not for other lymphoid markers or cytokeratin. Electron microscopy showed interdigitating cytoplasmic processes with junctions but no external lamina. The differential diagnosis includes carcinoma, lymphomas, and a variety of myxoid sarcomas. The tumor recurred within a few months and displayed increased nuclear pleomorphism and lymphatic invasion but the patient appears free of disease 3 years after the further excision. This case extends the spectrum of follicular dendritic cell sarcoma in soft tissue sites.- - - - - - - - - - ranking = 1keywords = lymphoma (Clic here for more details about this article) |
4/236. Waldenstrom's macroglobulinaemia of the breast detected by colour Doppler ultrasound.Waldenstrom's macroglobulinaemia (lymphoplasmacytoid lymphoma) is a low grade B cell non-Hodgkin's lymphoma. The majority of patients present with advanced disease. lymphoma of the breast is rare and usually arises as part of a disseminated disease process. A case of disseminated Waldenstrom's macroglobulinaemia is reported in which the breast was involved. The findings using standard mammographic and ultrasound techniques were non-specific and only when colour Doppler examination was performed could an abnormality be detected.- - - - - - - - - - ranking = 2keywords = lymphoma (Clic here for more details about this article) |
5/236. Multiple primary cancers and HPV infection: are they related?Multiple primary cancers have been reported with increasing frequency in recent years, but the presence of foreign dna sequences of infectious agents in tumours arising in the same patient has so far not been investigated. We report a case of a patient with Hodgkin's lymphoma, an "in situ" cervix carcinoma and an adenocarcinoma of the right and left mammary gland. In all the tumour samples we detected the presence of dna genomic sequences of Papillomavirus type 16. Our results suggest that HPV infection may be an exogenous risk factor even in second primary tumours of non-epithelial origin.- - - - - - - - - - ranking = 1keywords = lymphoma (Clic here for more details about this article) |
6/236. High grade MALT-lymphoma of the breast.A 65-year-old woman presented with a rapidly growing breast tumor, initially diagnosed as a carcinoma. histology showed a breast lymphoma of high grade MALT-type. A lymphoma should always be considered in the differential diagnosis of a breast tumor, because it needs a different work-up and treatment. The subgroup of NHL of Mucosa-Associated-Lymphoid-Tissue origin has different clinical behaviour, as illustrated in this report.- - - - - - - - - - ranking = 6keywords = lymphoma (Clic here for more details about this article) |
7/236. Primary non-Hodgkin's lymphoma of the breast: breast conservation therapy in two patients.We report two patients with primary non-Hodgkin's lymphoma of the breast who were treated with breast conservation therapy. These two patients were diagnosed with primary breast lymphoma by fine-needle aspiration cytology and underwent tumorectomy followed by adjuvant chemoradiation therapy. follow-up studies showed that the two patients were free of disease for two and three years, respectively. To date, there exists no therapeutic standard for this disease and there is no survival advantage for patients who undergo radical mastectomy. Despite the rarity of lymphoma in the breast, a preoperative accurate diagnosis is essential so that unnecessary, extended breast ablation or delayed treatment is avoided. Cytologic diagnosis of breast lymphoma is an easy procedure and provides guidance for appropriate preoperative management. early diagnosis combined with breast conservation therapy and systemic adjuvant therapy results in a favorable outcome for patients with breast lymphoma.- - - - - - - - - - ranking = 9keywords = lymphoma (Clic here for more details about this article) |
8/236. Orbital metastasis due to interval lobular carcinoma of the breast: a potential mimic of lymphoma.A 53-year-old woman had an orbital mass composed of a neoplastic small round cell infiltrate and no apparent extraorbital primary tumor. Although the initial diagnosis was primary orbital lymphoma, a combination of mucin histochemistry and immunohistochemical staining for cytokeratin and estrogen receptors led to the discovery of an impalpable lobular carcinoma of the breast. We discuss how detailed histopathological assessment can lead to beneficial therapy.- - - - - - - - - - ranking = 5keywords = lymphoma (Clic here for more details about this article) |
9/236. Postmastectomy malignant lymphoma.Postmastectomy lymphedema (PML) is a morbid condition occurring in patients with breast carcinoma treated with radical/modified radical mastectomy. Postmastectomy angiosarcoma (PMA) is the most common neoplasia seen in these patients. Primary malignant lymphoma arising in PML is a rare neoplasia and 3 cases have been reported until now. In this report a patient with diffuse large cell lymphoma (DLCL) arising in PML is reported and the other three cases are reviewed.- - - - - - - - - - ranking = 6keywords = lymphoma (Clic here for more details about this article) |
10/236. Bilateral breast MALT lymphoma: a case report and review of the literature.breast lymphoma is a rare disease. Both primary and secondary breast involvement have been reported. Most primary breast lymphomas are high-grade malignant neoplasms, mainly large cell and Burkitt type. Low-grade lymphomas of the breast, particularly mucosa-associated lymphoid tissue (MALT) lymphomas, have been exceedingly rare. In this report we present a patient with bilateral breast involvement by MALT lymphoma. Our patient developed localized MALT lymphoma in both breasts in a sequential fashion. She was treated with bilateral lumpectomy, followed by radiation therapy to both breasts. The patient is alive and well more than 1 year after therapy with no recurrence. We believe this is the first such case described in detail in the literature.- - - - - - - - - - ranking = 10keywords = lymphoma (Clic here for more details about this article) |
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