1/27. brucellosis in a mother and her young infant: probable transmission by breast milk.brucellosis, although primarily a zoonotic infection, is also a threat for human health. infection can be transmitted to humans through direct contact with infected animals, products of conception, or animal discharges, and through consumption of potentially infected milk, milk products, or meat. Human-to-human transmission is rare. There have been case reports of transmission via blood transfusion and bone marrow transplantation from infected donors. Sexual intercourse is a possible means of transmission. Neonatal infection can be acquired transplacentally or during delivery. This report describes a mother with brucellosis who probably transmitted the infection to her 3-month-old baby by breast milk.- - - - - - - - - - ranking = 1keywords = animal (Clic here for more details about this article) |
2/27. Brucella spondylitis: an important treatable cause of low backache.OBJECTIVES: This study was undertaken to see if brucella spondylitis existed as a cause of backache in Mumbai and to identify the clinical setting in patients of backache where brucella serology is indicated. methods: In 18 months (June 1996-Dec. 1997) we performed tube agglutination test (TAT) for brucella melitensis and abortus on 72 patients of low backache from Orthopaedics Department of a teritary health centre. All 72 patients satisfied the inclusion and exclusion criteria designed to exclude radiologically detectable congenital or degenerative cause of backache. RESULTS: Six out of 72 patients were seropositive for brucellosis. All six patients had either history of animal contact or ingestion of raw milk or milk product (cheese or paneer). The lumbosacral backache was severe, radiating to the legs and straight leg raising test was significantly positive, they had marked tenderness on spinous process of lower lumbar vertebrae. Changes of brucella spondylitis were present on plain radiogram of lumbosacral spine in three patients. Four patients had abnormalities on bone scintigraphy. CONCLUSION: Low backache of brucella spondylitis closely simulates pain of prolapsed intervertebral disc. Serologic testing for brucellosis is an important step in management of such patients, especially when history of animal contact or raw milk or milk product ingestion is present, as the disease can be eminantly treated with antibiotics.- - - - - - - - - - ranking = 1keywords = animal (Clic here for more details about this article) |
3/27. meningoencephalitis in brucellosis.Human brucellosis, more specifically neurobrucellosis, is a less commonly reported disease in india; although, animal brucellosis and seroprevalence in specific areas is well reported. We are reporting 4 cases of neurobrucellosis presenting as meningoencephalitis. diagnosis was confirmed by serological test and agglutination titre was > 1:320 in all the patients. All these patients had close contact with animals and history of raw milk ingestion was present in 3 cases. The aim of presenting these cases is to create awareness among physicians while treating meningitis in persons, engaged in occupations related to brucellosis or having a history of ingestion of raw milk or milk product.- - - - - - - - - - ranking = 1keywords = animal (Clic here for more details about this article) |
4/27. Poor perinatal outcome associated with maternal brucella abortus infection.BACKGROUND: Reports suggest that perinatal infection with brucella abortus does not cause poor obstetric outcomes, because of protective mechanisms in the human, not seen in animal species. CASE: We report a case of maternal brucellosis resulting in preterm labor, chorioamnionitis, placental abruption, and delivery of a live-born infant at 25 weeks' gestational age. Both maternal blood cultures and amniotic fluid cultures were positive for B abortus species, and delivery occurred despite aggressive antibiotic and tocolytic therapy. CONCLUSION: Maternal infection with B abortus during pregnancy can lead to significant perinatal morbidity, casting doubt on reports that human pregnancy is resistant to such infection.- - - - - - - - - - ranking = 0.5keywords = animal (Clic here for more details about this article) |
5/27. Autoimmune hepatitis triggered by Brucella infection or doxycycline or both.Autoimmune hepatitis is a disorder of unknown aetiology in which progressive destruction of the hepatic parenchyma occurs, often progressing to cirrhosis. hepatitis a, Ebstein-Barr virus and measles virus have been identified as triggers for autoimmune hepatitis in susceptible individuals. There are also reports about herbal medicine and minocycline. A case with autoimmune hepatitis triggered by Brucella infection or doxycycline, or both, is presented. An 11-year-old female patient treated with six weeks of doxycycline and three weeks of streptomycine for brucellosis presented with histologically proven autoimmune hepatitis (AH) and responded to corticosteroid treatment. Since neither brucellosis nor doxcycyline as triggering factors for AH have been described so far, these two entities are discussed and the literature reviewed.- - - - - - - - - - ranking = 1.1356324657506keywords = hepatitis (Clic here for more details about this article) |
6/27. Spontaneous bacterial peritonitis due to Brucella infection.Brucella infection is a systemic disease, but the microorganism rarely causes infections in the gastrointestinal system such as hepatitis, cholecystitis, colitis and pancreatitis. Spontaneous bacterial peritonitis due to Brucella is extremely rare. Herein, we report a case of cirrhosis complicated with nongranulomatous hepatitis and peritonitis, both due to Brucella. A 63 year-old man with diabetes mellitus was admitted to hospital with complaints of weakness, backache, abdominal pain and abdominal swelling. On the basis of physical examination and laboratory findings, cryptogenic cirrhosis and spontaneous bacterial peritonitis were diagnosed. Due to persistent fever and backache, serum Brucella agglutination test was performed and found to be positive. brucella melitensis was isolated from ascitic fluid culture. liver biopsy findings revealed cirrhosis and a nongranulomatous hepatitis which was thought might be due to Brucella infection. doxycycline and rifampicin, in addition to diuretics were administered for spontaneous ascites infection due to Brucella. A week later, the patient's condition improved and he became afebrile. After two months of therapy, the ascites had almost disappeared.- - - - - - - - - - ranking = 0.42586217465648keywords = hepatitis (Clic here for more details about this article) |
7/27. Brucella: a rare causative agent of spontaneous bacterial peritonitis.We report a 54-year-old woman with hepatitis b-related chronic liver disease with ascites who developed spontaneous bacterial peritonitis. Blood and fluid cultures grew Brucella; the patient was working at an animal husbandry till one year ago. She responded to therapy with streptomycin and tetracycline.- - - - - - - - - - ranking = 0.64195405821883keywords = animal, hepatitis (Clic here for more details about this article) |
8/27. Case report: brucellosis: a re-emerging disease in thailand.brucellosis is a zoonotic disease prevalent in many countries, but it has been reported only once in thailand, 36 years ago. We describe here two consecutive cases of brucellosis in Bangkok, thailand. Both cases presented with prolonged fever and weight loss. Blood cultures taken from 2 patients yielded brucella melitensis. The slide agglutination test of blood samples were also positive, with a titer of 1:64 for antibodies to Brucella. The first patient responded to a combination of doxycycline, gentamicin, and ciprofloxacin; the other responded to doxycycline and rifampicin. brucellosis is a potential public health threat, therefore, preventive measures should be actively implemented. This clinical syndrome should be included in the differential diagnosis of patients presenting with prolonged fever, particularly those with contact to animals which could serve as reservoirs.- - - - - - - - - - ranking = 0.5keywords = animal (Clic here for more details about this article) |
9/27. Brucella osteomyelitis of the proximal tibia: a case report.brucellosis is a disease of domestic and wild animals that is transmittable to humans. Although endemic in some parts of the world, brucellosis is an uncommon human pathogen in the united states. The clinical presentation of brucellosis is nonspecific, and brucella osteomyelitis can produce lytic lesions on radiographs that resemble neoplasm. diagnosis can therefore be difficult unless a high index of suspicion is maintained. We present a case of brucella osteomyelitis of the proximal tibia that demonstrates these features.- - - - - - - - - - ranking = 0.5keywords = animal (Clic here for more details about this article) |
10/27. Etiological role of brucellosis in autoimmune hepatitis.To show that brucellosis may trigger autoimmune hepatitis (AIH), in addition to nonspecific liver involvement and toxic hepatitis, due to a class effect of tetracycline family used for treatment. We present a female patient admitted to our hospital due to partially improved fatigue and elevated liver enzymes following doxycycline and streptomycin usage for brucellosis. brucellosis is endemic in our country, turkey. It may involve any organ in the body. liver is frequently involved. doxycycline used for treatment occasionally may lead to hepatotoxicity. AIH is a necroinflammatory disease of the liver. Certain drugs (e.g. minocycline), toxins, and viruses (hepatitis b, hepatitis c, EBV, etc.) can trigger AIH. Only one case of AIH probably caused by doxycycline and brucellosis was reported. We discuss the relationship between brucellosis, AIH, and hepatotoxicity of doxycycline. brucellosis may trigger AIH.- - - - - - - - - - ranking = 1.1356324657506keywords = hepatitis (Clic here for more details about this article) |
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