1/238. Calcification in mucinous cholangiocellular carcinoma.Calcification is rarely seen in cholangiocellular carcinoma. We herein report the case of a 53 year-old man with calcification in a cholangiocellular carcinoma. Because imaging studies had revealed coarse calcified foci, hepatolithiasis was suspected pre-operatively. The patient underwent a laparotomy in which intra-operative cholangioscopy revealed no gallstones but did reveal an unsuspected tumor with abundant mucin. A left hepatic lobectomy with resection of the extrahepatic bile duct was performed. The tumor histology was mucinous adenocarcinoma with calcification. In the English language literature, we found 9 cases of cholangiocellular carcinoma with macroscopic calcification. Six of these cases were mucinous adenocarcinomas. Roentgenologic examination revealed coarse calcification in 7 cases and fine calcification in 2 cases. Clinicians should note that cholangiocellular carcinoma, especially the mucinous variant, may be accompanied by coarse calcification.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
2/238. Calcification of presumed ovarian carcinoma brain metastases following radiotherapy.Multiple brain metastases from ovarian carcinoma are rare. CT findings are reported in a case treated with whole brain radiation therapy and chemotherapy. Radiological complete-calcified brain metastases following treatment and long morphological changes occurred. Delayed neurological findings in relation to treatment are considered. Long survival with unmodified calcified lesions may suggest a stabilization of CNS disease.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
3/238. calcium oxalate crystals (Weddellite) within the secretions of ductal carcinoma in situ--a rare phenomenon.A case is described in which calcium oxalate (Weddellite) crystals were identified in an area of ductal carcinoma in situ of the breast. Seventy other cases were examined but no evidence of Weddellite was detected. This is evidently a rare phenomenon in carcinoma in situ.- - - - - - - - - - ranking = 0.60047072859678keywords = carcinoma, situ (Clic here for more details about this article) |
4/238. Recurrent ductal carcinoma in situ after total mastectomy.A case report is presented of a woman with recurrent DCIS occurring several years following a total mastectomy, the diagnosis of which was aided by a subpectoral saline implant. A discussion of factors associated with recurrence and a review of the literature is provided. A role for selective use of mammography in screening postmastectomy reconstructed breasts in patients at high risk for recurrence is suggested.- - - - - - - - - - ranking = 0.40031381906452keywords = carcinoma, situ (Clic here for more details about this article) |
5/238. Radial scar with microcalcification mammographic-pathologic correlation: case report.Radial scar, a descriptive term for a pathologic lesion, is composed of central area of fibroelastosis and distorted ducts, and peripheral zone of intraductal hyperplasia. This lesion often presents as a spiculated lesion, sometimes with microcalcifications, on mammography which may mimic malignancy such as tubular carcinoma. We report a case of radial scar with clustered microcalcifications incidentally found in the screened mammogram.- - - - - - - - - - ranking = 0.1keywords = carcinoma (Clic here for more details about this article) |
6/238. Neuronal cytoskeletal changes are an early consequence of repetitive head injury.While neuropathological studies have established the pathology of dementia pugilistica to be similar to that of Alzheimer's disease, there is little information about the early histological changes caused by the repetitive trauma that eventually produces dementia pugilistica. We have examined the brains of four young men and a frontal lobectomy specimen from a fifth, age range 23-28 years, all of whom suffered mild chronic head injury. There were two boxers, a footballer, a mentally subnormal man with a long history of head banging, and an epileptic patient who repeatedly hit his head during seizures. The four autopsy cases were widely sampled; the lobectomy specimen was serially sliced after fixation. Routine stains were performed; inmmunostaining included beta-amyloid precursor protein, amyloid beta-protein (Abeta), tau and apolipoprotein E (apoE). Pathological findings in all five cases were of neocortical neurofibrillary tangles (NFTs) and neuropil threads, with groups of tangles consistently situated around blood vessels in the worst affected regions. No Abeta immunoreactivity was detected. The amount of neuronal apoE expression varied widely between the cases with no clear relation to the NFTs. The apoE genotype was determined in only two cases (both epsilon3/epsilon3). It appears that repetitive head injury in young adults is initially associated with neocortical NFT formation in the absence of Abeta deposition. The distribution of the tau pathology suggests that the pathogenesis of cytoskeletal abnormalities may involve damage to blood vessels or perivascular elements.- - - - - - - - - - ranking = 7.8454766130414E-5keywords = situ (Clic here for more details about this article) |
7/238. Ductal adenocarcinoma of the pancreas with intratumoral calcification.We present two cases of ductal adenocarcinoma of the pancreas with intratumoral calcification. The two cases indicate two different etiologies for intratumoral calcification in ductal adenocarcinoma. Thus, the possibility of adenocarcinoma should be considered when a tumor with intratumoral calcification is found, although the incidence of intratumoral calcification in the ductal adenocarcinoma of the pancreas remains rare.- - - - - - - - - - ranking = 0.8keywords = carcinoma (Clic here for more details about this article) |
8/238. Renal cell carcinoma with massive osseous metaplasia and bone marrow elements.Focal calcifications are frequently seen in renal masses and may be present in renal cell carcinomas. Metaplastic bone formation, on the other hand, is a rare event. We report a unique case of a large calcified renal cell carcinoma with massive osseous metaplasia and bone marrow elements. The clinical and pathologic differential diagnosis for this tumor is discussed along with a review of the literature on this unusual phenomenon.- - - - - - - - - - ranking = 0.6keywords = carcinoma (Clic here for more details about this article) |
9/238. Supradiaphragmatic manifestations of papillary serous adenocarcinoma of the ovary.AIM: To illustrate unusual patterns of isolated supradiaphragmatic presentation and relapse of papillary serous adenocarcinoma of the ovary. methods: Retrospective study of five women (26-57 years) managed by a specialist gynaecological oncology unit. RESULTS: Three women relapsed in the neck, mediastinal or axillary nodes 3 to 5 years after complete abdomino-pelvic remission. Two women presented with pleural or cervical lymph node metastases respectively 2 and 13 years before the primary pelvic tumour was discovered. Clinical presentations in these five women mimicked metastatic thyroid and breast cancer and mesothelioma. In four of the five woman supradiaphragmatic nodal disease was heavily calcified. CONCLUSION: women with papillary serous ovarian cancer may develop supradiaphragmatic disease without evidence of peritoneal metastasis or primary pelvic tumours. Isolated supradiaphragmatic relapse may occur many years after complete remission of abdomino-pelvic disease. Calcification in supradiaphragmatic lymph nodes should not be assumed to be due to old granulomatous disease as this may be the only clue to relapsing disease. review of prior histology and use of immunohistochemical stains were valuable in diagnosis of these cases.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
10/238. Patent internal and external carotid arteries beyond an occluded common carotid artery: report of a case diagnosed by color Doppler.Occlusion of the common carotid artery (CCA) is most often associated with thrombosis of the distal vessels. In rare cases, however, a weak antegrade flow can still be detected in the internal carotid artery (ICA). This patency is the result of a retrograde perfusion of the ipsilateral external carotid artery (ECA) via its collaterals. Such situation should not be ignored since bypass surgery can easily allow for effective restoration of flow. Most authors agree to say that color flow duplex imaging (CFDI) has now become the hallmark to detect a patent ICA in spite of a CCA occlusion.- - - - - - - - - - ranking = 7.8454766130414E-5keywords = situ (Clic here for more details about this article) |
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