1/2. An office laboratory panel to assess vaginal problems.In determining the cause of vaginal complaints, the routine use of four simple tests ("the vagina panel") enables the physician to identify pathogens (candida, gardnerella, trichomonas), pathologic processes (inflammation, estrogen deficiency) and, in most instances, a healthy vagina. time and money are saved. The specimens can be collected in one minute during a pelvic examination. The panel can provide the answers to eight essential questions in two minutes of observer time, with supplies costing about $2.- - - - - - - - - - ranking = 1keywords = deficiency (Clic here for more details about this article) |
2/2. Chronic vaginal candidiasis responsive to biotin therapy in a carrier of biotinidase deficiency.BACKGROUND: Many patients experience recurrent or persistent episodes of vaginal candidiasis. Some of these women might be carriers of an inborn error of biotin metabolism (either biotinidase deficiency or holocarboxylase synthetase activity). These women might benefit from administration of pharmacologic amounts of biotin. CASE: A 38-year-old gravida 2, para 2 carrier of biotinidase deficiency presented with a 14-month history of persistent vaginal candidiasis, despite appropriate therapy. After 3 months of pharmacologic doses of biotin, her symptoms resolved completely. CONCLUSION: Given that 1 in every 123 individuals is predicted to be a carrier of biotinidase deficiency, there might be other women with chronic vaginal candidiasis who will respond to biotin administration.- - - - - - - - - - ranking = 42929.052744783keywords = biotinidase deficiency, biotinidase, deficiency (Clic here for more details about this article) |