1/13. Placental candidiasis: report of four cases, one with villitis.Four cases of placental candidiasis, an uncommon complication of rupture of the membranes, are presented. In addition to chorioamnionitis, in one of these cases villitis was also observed. Villitis is a rare occurrence in Candida infection and this represents only the second case in the literature. The involvement of villi may be suggestive of blood-borne infection. However, since neither the mother nor the foetus presented any signs of systemic dissemination, the authors suggest a hypothesis of contamination of the villi from foci of chorioamnionitis.- - - - - - - - - - ranking = 1keywords = chorioamnionitis (Clic here for more details about this article) |
2/13. candida albicans chorioamnionitis associated with preterm labor and sudden intrauterine demise of one twin. A case report.BACKGROUND: Although cervicovaginal Candida infections occur in 20-25% of pregnancies, the incidence of ascending infection in these cases is only 0.8%, and such infection rarely causes chorioamnionitis. CASE: Sudden intrauterine fetal demise (IUFD) of twin A occurred in a diabetic primigravida presenting with a twin pregnancy and preterm labor at 33 weeks of gestation. Placental pathology and autopsy of the stillborn twin revealed extensive chorioamnionitis and fetal sepsis in the presence of candida albicans. Twin B was unaffected. CONCLUSION: In this case, C albicans chorioamnionitis seemed to be associated with sudden IUFD.- - - - - - - - - - ranking = 3.5keywords = chorioamnionitis (Clic here for more details about this article) |
3/13. Candida chorioamnionitis after serial therapeutic amniocenteses: a possible association.BACKGROUND: Reduction amniocentesis is used in cases of severe polyhydramnios to decrease maternal discomfort and the risk of preterm labor. In a medline search (1966 to present, English language, keywords: amniocentesis, chorioamnionitis), no report of Candida chorioamnionitis after serial reduction amniocentesis exists. CASE: A 29-year-old primigravida with a history of four therapeutic amniocenteses for idiopathic polyhydramnios developed preterm labor at 30 and 5/7 weeks' gestation, rupture of membranes, and candida albicans chorioamnionitis. Despite aggressive therapy with amphotericin b, the neonate succumbed to overwhelming systemic candidiasis. CONCLUSION: Serial amniocentesis may place patients at elevated risk for Candida chorioamnionitis and subsequent preterm delivery. Clinicians should consider early diagnostic amniocentesis in patients in preterm labor with a history of prior amniocentesis, and the routine Gram stain and culture of amniotic fluid.- - - - - - - - - - ranking = 4keywords = chorioamnionitis (Clic here for more details about this article) |
4/13. Missed abortion complicated by Candida infection in a woman with rested IUD.Although Candida species are frequent saprophytes of the female genital tract, chorioamnionitis or intrauterine fetal infections are rarely caused by these fungi. The present report describes a 34-year-old woman G2, P2, presenting with vaginal bleeding in the 11.6 weeks of gestation. Clinical and sonographic examination revealed a missed abortion and rested IUD. Histopathologically, a fungal chorioamnionitis due to Candida spp. was found at the curetting material, confirmed by detection of C. albicans infection on mycological culture. Foreign intrauterine bodies, like IUD's and cerclage sutures predispose to fungal chorioamnitis or fetal infections. This conditions urge repetetive search for Candida spp. to establish early anti-fungal therapy which may be therapeutic for this hithero rare intrauterine infection.- - - - - - - - - - ranking = 1keywords = chorioamnionitis (Clic here for more details about this article) |
5/13. Intra-uterine Candida infection: a report of four infected fetusses from two mothers.Although candida albicans is a frequent inhabitant of the female genital tract, chorioamnionitis is rarely caused by this fungal organism. In this report we present two cases with manifest Candida chorioamnionitis. The first case is a twin pregnancy with premature delivery and survival of both twins. The second case is a pregnancy with intra-uterine contraceptive device in situ ending in a midtrimester abortion, followed by the next pregnancy also ending in an abortion in the second trimester. Possible triggers responsible for the increased invasiveness of otherwise benign Candida vaginitis are discussed. Foreign intra-uterine bodies such as contraceptive devices and cerclage sutures necessitate repetitive search for Candida species infection, and prompt adequate antifungal treatment in cases of documented infection. Both cases of the present report add further substantial evidence to the hypothesis of amniotic infection by ascending transcervical infection. The frequent concomitant cervical infections with other infectious agents as well as antibiotherapy influencing the normal Lactobacillary defence mechanisms are both likely to increase the risk. Systemic debilitating diseases that promote invasiveness are briefly discussed.- - - - - - - - - - ranking = 1keywords = chorioamnionitis (Clic here for more details about this article) |
6/13. Intrauterine fetal death apparently due to Candida chorioamnionitis.There is an increasing awareness of the association between candida albicans chorioamnionitis and preterm labor. We present a case of intrauterine fetal death caused by Candida chorioamnionitis at the 21 weeks gestation in a patient with an intrauterine device (IUD).- - - - - - - - - - ranking = 3keywords = chorioamnionitis (Clic here for more details about this article) |
7/13. Candida chorioamnionitis diagnosed by amniocentesis with subsequent fetal infection.Isolation of candida albicans from the vaginal secretions of pregnant women occurs with an incidence of 5-23%. Intrauterine infection caused by Candida during pregnancy is relatively rare; only 81 cases, all diagnosed after delivery, have been reported. We report six cases of candidal chorioamnionitis diagnosed by amniocentesis and confirmed by histologic studies, associated with preterm labor and delivery of five viable infants. Three of the six maternal patients had intrauterine contraceptive devices in situ. Three infants had a diagnosis of congenital cutaneous candidiasis and two had congenital systemic candidiasis, one with monilial pneumonia, and one with meningitis and septicemia. All viable neonates were treated successfully. The sixth, a very immature infant, died soon after delivery. Torulopsis (Candida) glabrata was isolated from this amniotic fluid. C. Albicans is a pathogen that potentially may cause chorioamnionitis and has been associated with high mortality (94%) in infants weighing less than 1500 gm. Use of amniocentesis in patients with preterm labor may allow early detection of subclinical candidal chorioamnionitis, thus guiding appropriate perinatal management.- - - - - - - - - - ranking = 3.5keywords = chorioamnionitis (Clic here for more details about this article) |
8/13. Candida chorioamnionitis and intra-uterine contraceptive device.In spite of the very common occurrence of vaginal candidiasis in pregnant women (1), the uterus is seldom affected. There are few reports in the literature of intrauterine infection. The present paper presents a case of placental and fetal candidiasis in association with the presence of an intra-uterine contraceptive device (IUD).- - - - - - - - - - ranking = 2keywords = chorioamnionitis (Clic here for more details about this article) |
9/13. prenatal diagnosis of candida albicans chorioamnionitis.The use of diagnostic amniocentesis has been proposed for the evaluation of patients with clinical suspicion of chorioamnionitis, such as those with premature rupture of membranes and premature labor. We describe a patient in whom the diagnosis of Candida chorioamnionitis was made after diagnostic amniocentesis with the assistance of a simple and rapidly performed potassium hydroxide smear.- - - - - - - - - - ranking = 3keywords = chorioamnionitis (Clic here for more details about this article) |
10/13. Congenital Candida pneumonia in a preterm infant.A 24 week gestation survivor of congenital Candida pneumonia who received prompt antifungal treatment and modern neonatal intensive care is reported. It was an unusual case in that fungal chorioamnionitis occurred without a foreign body in the maternal genital tract. early diagnosis and treatment of congenital fungal pneumonia was possible because of prior knowledge of the obstetric history. amphotericin b was successfully used for the treatment of this condition but combination with fluconazole (a fungistatic agent) was unsatisfactory and may be undesirable. dexamethasone therapy to assist extubation was instituted once the fungal infection had been successfully controlled.- - - - - - - - - - ranking = 0.5keywords = chorioamnionitis (Clic here for more details about this article) |
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