1/9. Constrictive pericarditis caused by candida glabrata in an immunocompetent patient: case report and review of literature.Candida pericarditis is a rare disease described mostly in patients with recent cardiothoracic surgery or debilitating chronic diseases and is generally considered to be associated with high mortality. To our knowledge, we report the first case of Candida pericarditis in a healthy host who had not undergone thoracic surgery and the first documented case and cure of pericarditis caused by C. glabrata. The most probable underlying factor in the development of this pericarditis was the abdominal surgery the patient underwent to correct a gastrogastric fistula, without an intraabdominal leak, which developed 10 y after surgical gastric stapling for weight reduction. The literature on Candida pericarditis is reviewed. If Candida pericarditis is diagnosed early and treated with a combined medical and surgical approach, the prognosis today is much more favorable than that previously reported.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/9. Endogenous Candida endophthalmitis after two consecutive procedures of suction dilatation and curettage.Endogenous Candida endophthalmitis (ECE) is a rare disease. We present a patient with Candida endophthalmitis after two consecutive procedures of suction dilatation and curettage for elective abortion. A 24-year-old single woman who received a suction dilatation and curettage one week ago developed pain and blurred vision in the right eye. Endogenous Candida endophthalmitis was diagnosed and treated with oral fluconazole and pars plana vitrectomy with adjunction of intravitreal amphotericin b injection. The vitreous culture revealed candida albicans. The vitreous inflammation subsided greatly after the initial treatment but flared up after the second dilatation and curettage for incomplete abortion 5 days after the vitrectomy. The oral fluconazole was replaced by intravenous amphotericin b, and a second vitrectomy with injection of intravitreal amphotericin b was performed. Postoperatively, the intraocular inflammation resolved gradually. Six months after the second vitrectomy, the best-corrected visual acuity in the right eye was 20/25. The excellent visual acuity of this patient was attributed to the early diagnosis and aggressive treatment. For patients with mild disease, less toxic oral fluconazole as the systemic antifungal agent instead of more toxic intravenous amphotericin b has been recommended. For those with advanced disease, intravitreal amphotericin b in conjunction with vitrectomy has been advocated by many eye surgeons.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/9. Disseminated pulmonary candidiasis complicating hyperimmunoglobulin E (Job's) syndrome.Hyperimmunoglobulin E (Job's) syndrome is a rare disease characterized by recurrent pneumonia and sinusitis, pneumatoceles, chronic dermatitis, and elevated serum levels of immunoglobulin e. In this report, the author presents a case of disseminated pulmonary candidiasis in a young man with hyperimmunoglobulin E syndrome. His chest radiograph showed reticulonodular opacities in both lungs. Computed tomography scans revealed multiple pulmonary nodules and hilar and mediastinal enlarged lymph nodes.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/9. Mycotic aneurysms affecting both lower legs of a patient with Candida endocarditis--endovascular therapy and open vascular surgery.The purpose of this study was to report the endovascular and open surgery treatment of Candida-associated mycotic aneurysms in both lower limbs. A 53-year-old patient suffering from Candida endocarditis following aortic valve replacement developed mycotic aneurysms in both lower limbs. The angiography revealed a large aneurysm of the tibioperoneal trunk affecting the right leg. In the left leg, sacculation had developed in section III of the popliteal artery. The right aneurysm was obliterated by embolization with coils. On the left side, the large aneurysm of the popliteal artery was resected; vascular continuity was re-established by interposing a segment of the patient's greater saphenous vein. The postoperative course was uneventful. Mycotic aneurysm is a rare disease. A site in the crural vessels is regarded as exceptionally seldom. To our knowledge, no Candida-associated mycotic aneurysm has been described in this region before. Both endovascular treatment and open surgery proved to be successful.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
5/9. Congenital cutaneous candidiasis: report of four cases and review of the literature.Congenital cutaneous candidiasis (CCC) is a rare disease acquired by an ascending route, liable to affect the offspring of pregnant women suffering from vulvovaginitis. The cutaneous lesions are present at birth or within the first hours of life. Some infants may present with respiratory distress or clinical signs of sepsis during the first 2 days of life. We report four new cases of CCC, three of which presented transient respiratory distress and clinical signs of sepsis with hepatosplenomegaly. The evolution was favourable in all three cases with topical and oral therapy. We emphasize the self-limited character of this disease, although preterm infants may be at risk of systemic spread. Only one infant presented paronychia as a late complication.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
6/9. herpes simplex esophagitis in a renal transplant patient treated with cyclosporine A: a case report.herpes simplex esophagitis is a rare disease occurring mostly in immunocompromised and cancer patients. We report the first case of herpes esophagitis in a renal transplant patient treated with cyclosporine A while on chronic steroid therapy. With the increasing use of cyclosporine A in transplant patients, the incidence of herpes esophagitis may increase. The disease is suggested endoscopically by its typical appearance. The diagnosis is confirmed by cytology, tissue studies, and viral cultures. Based on the limited knowledge of the natural history of herpetic esophagitis and lack of prospective antiviral trials, symptomatic therapy with viscous Xylocaine appears reasonable. The definitive role of antiviral therapy is yet to be clarified.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
7/9. Candidal renal papillary necrosis: report of a case and review.Renal papillary necrosis (RPN) due to Candida is a rare disease with only 19 cases reported over the past 37 years. But the diagnosis in 17 of the 19 cases was not made until a necropsy was carried out. The 2 cases that were diagnosed antemortem had radiographic sonography. A singapore case with candidal RPN was described in detail. Candidal RPN was associated with underlying diseases in all these cases. The disease may be more frequently encountered in the future with the advent of radiographic tools like sonography which was not described prior to 1980. Indeed, patients with underlying diseases who develop persistent candiduria should have radiographic investigation of the urinary tract to detect candidal RPN to that early remedial measures can be carried out.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
8/9. Post-traumatic costochondritis caused by candida albicans. Aetiology, diagnosis and treatment.Candida costochondritis is a rare disease of complex aetiology. Pathogenetic factors range from postoperative and posttraumatic complications to haematogenous dissemination in intravenous drug addicts. In addition to clinical examination, possible diagnostic procedures include scintiscan and magnetic resonance imaging. The treatment of choice is extensive debridement and resection of the structures affected by the inflammatory process. The long-term prognosis is good.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
9/9. Candida endocarditis in an infant.Infective endocarditis is a rare disease in infants. A 1-year-old boy with a large candida albicans vegetation in the right atrium and superior vena cava was operated on successfully. During the newborn period he had had a right transverse colostomy for Hirschsprung's disease. Ten months later a subsequent rectosigmoidectomy and direct anastomosis were performed, but because of peritonitis that followed a leak at the site of the anastomosis parenteral nutrition was needed for 8 weeks. The probable source of Candida was an infected intravenous line.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |