1/189. radium-induced malignant tumors of the mastoid and paranasal sinuses.In the records of 5,058 persons with therapeutic or occupational exposure to radium, 21 patients with carcinoma of the mastoid and 11 with malignant tumors of the paranasal sinuses were identified. Tumor induction times were 21-50 years for mastoid tumors (median, 33) and 19-52 years for paranasal sinus tumors (median, 34). Dosimetric data are given for the patients whose body burdens of radium have been measured. We found a high proportion of mucoepidermoid carcinoma, comprising 38% of the mastoid and 36% of the paranasal sinus tumors. Three patients had antecedent bone sarcoma at 20, 11, and 5 years, respectively, and a bone sarcoma was discovered at autopsy in a fourth patient. Radiographic changes in the mastoid and paranasal sinuses were similar to those seen in nonradium malignant tumors. More than 800 known persons exposed to radium before 1930 and another group of unknown size who received radium water or injections of radium from physicians are still alive and at risk of developing malignant tumors of the mastoid and paranasal sinuses.- - - - - - - - - - ranking = 1keywords = paranasal sinus, paranasal, sinus (Clic here for more details about this article) |
2/189. Recurrent squamous-cell carcinoma arising in sacrococcygeal pilonidal sinus tract: report of a case and review of the literature.PURPOSE: carcinoma arising in a pilonidal sinus is a rare complication. This study reports the case of a patient with recurrent squamous-cell carcinoma arising in a sacrococcygeal pilonidal sinus tract. methods: This patient was treated with a wide local excision and mesh grafts. Three months later the patient was treated with adjuvant radiation therapy. RESULTS: The patient died two years later from recurrence in inguinal lymph nodes, liver, and lungs. CONCLUSION: Some authors propose consideration of treatment with adjuvant chemotherapy and radiation therapy in addition to complete local excision as a possible means to decrease the local recurrence rate.- - - - - - - - - - ranking = 0.028716231546541keywords = sinus (Clic here for more details about this article) |
3/189. Squamous cell carcinoma in chronic ulcerative lesions: a case report and literature review.A case report and literature review are presented involving a fatal case of squamous cell carcinoma of the lower extremity. The unique aspects of this patient include the young age at presentation (35 years old), and the association with both a burn scar (Marjolin's) ulcer and a draining osteomyelitis fistulus tract. Epidemiologic data for Marjolin's ulcers as well as squamous cell carcinoma associated with draining sinus tracts of osteomyelitis are reviewed, in addition to the recommended management of such patients. The case presented is a reminder of the need to maintain a high index of suspicion for malignant transformation within ulcerative lesions.- - - - - - - - - - ranking = 0.0047860385910901keywords = sinus (Clic here for more details about this article) |
4/189. Fine-needle aspiration cytology of metastatic squamous-cell carcinoma arising in a pilonidal sinus, with literature review.Fewer than 50 cases of carcinoma arising in a pilonidal sinus have been reported, with only 5 patients having documented inguinal lymph node metastases. This is the first report of the fine-needle aspiration (FNA) diagnosis of this uncommon clinical situation of squamous-cell carcinoma arising in a pilonidal sinus, metastatic to an inguinal lymph node. We report on a 59-yr-old male with squamous-cell carcinoma arising in a pilonidal sinus who presented with inguinal adenopathy. FNA biopsy of a lymph node was performed, resulting in a diagnosis of metastatic squamous-cell carcinoma. FNA biopsy is useful in the evaluation of patients with inguinal adenopathy and a history of malignancy arising in a pilonidal sinus. The possibility of this rare complication should also be considered when metastatic squamous-cell carcinoma to an inguinal lymph node is diagnosed by FNA cytology in patients having an unknown primary except for a change in a long-standing pilonidal cyst.- - - - - - - - - - ranking = 0.038288308728721keywords = sinus (Clic here for more details about this article) |
5/189. Vascular transformation of sinuses in bilateral cervical lymph nodes.BACKGROUND: Vascular transformation of sinuses (VTS) in lymph node has been infrequently reported. We present a case of incidental VTS in bilateral cervical nodes discovered at the time of operation for tongue cancer. methods: Standard histopathologic review was undertaken. RESULTS: In this case, a spectrum of varied vasoformative patterns involving lymph nodes in either a pan-nodal or localized fashion were identified. The hilum was occupied by smooth muscle proliferation and adipose tissue. Two nodes also displayed similar features of angiolipomatous hamartoma. No metastatic carcinoma was found in lymph nodes with VTS. CONCLUSIONS: This case suggests that lymphovenous congestion and distention represented the major cause through which VTS developed.- - - - - - - - - - ranking = 0.023930192955451keywords = sinus (Clic here for more details about this article) |
6/189. Fatal cutaneous squamous cell carcinoma with extension through the maxillary sinus and orbit into the brain.Cutaneous squamous cell carcinomas may cause death by metastasis or by local extension. We describe a deeply invasive cutaneous squamous cell carcinoma that caused death by direct extension into the brain.- - - - - - - - - - ranking = 0.01914415436436keywords = sinus (Clic here for more details about this article) |
7/189. The role of positron emission tomography in occult primary head and neck cancers.PURPOSE: To evaluate the utility of positron emission tomography (PET) fluorodeoxyglucose (FDG) imaging in the workup of unknown primary head and neck tumors. methods: Fourteen patients with squamous cell carcinoma of cervical lymph node metastasis of unknown primary origin (clinical stage N2-N3) were studied prospectively. The patients underwent conventional workup, including physical examination, computed tomography, and random biopsies of the potentially suspected sites. If no primary site was found, 8 to 13 mCi of FDG was given intravenously, and whole-body scans with standardized uptake values were obtained. The results of FDG-PET imaging were compared with clinical, CT, and histopathologic findings. To eliminate bias, PET scans were reviewed by nuclear medicine physicians who had no previous knowledge of the other findings. RESULTS: PET identified the location of primary tumor in three patients: lung hilum, base of tongue, and pyriform sinus. These lesions were pathologically confirmed. All these primary sites were not visualized on CT or physical examination, except for a pyriform sinus lesion, which was seen on CT, but initial biopsy result was negative. In one patient, the initial PET did not identify a primary tumor, but a nasopharyngeal carcinoma was identified in post-radiation therapy follow-up PET. In the remaining nine patients, a primary lesion was never found. All cervical lymph nodes detected by CT were identified by PET. DISCUSSION: A previously unknown primary tumor can be identified with FDG-PET in about 21% of the patients in our prospective series. PET can be of value in guiding endoscopic biopsies for histologic diagnosis and treatment options.- - - - - - - - - - ranking = 0.0095720771821802keywords = sinus (Clic here for more details about this article) |
8/189. Squamous cell carcinoma arising in an intradiploic epidermoid cyst.A 71-year-old woman presented with the symptoms of a posterior cranial fossa mass. CT and MRI revealed a lytic lesion in the occipital bone and a tumour infiltrating the dura mater, venous sinuses and cerebellum. Histopathology demonstrated a moderately differentiated squamous cell carcinoma arising from a primarily intradiploic epidermoid cyst. Despite surgery and radiotherapy, the tumour progressed and the patient died 1 year later.- - - - - - - - - - ranking = 0.0047860385910901keywords = sinus (Clic here for more details about this article) |
9/189. Metastasic oesophageal carcinoma to the paranasal sinuses--a case report.Metastasis to the paranasal sinuses is rare. We report a case of a patient with metastasis to the paranasal sinuses from carcinoma of the oesophagus. Our patient presented with symptoms mimicking the more common acute sinusitis. Although rare, metastatic disease of the paranasal sinuses should be considered especially in patients with a known primary carcinoma elsewhere presenting with sinu-nasal symptoms.- - - - - - - - - - ranking = 0.78256381636887keywords = paranasal sinus, paranasal, sinus (Clic here for more details about this article) |
10/189. Unusual case of non-exophytic invasive penile squamous cell cancer arising from a chronic sinus tract.We present an unusual case of an extremely well-differentiated but deeply invasive squamous cell carcinoma of the penis without an obvious external lesion, arising from a chronic draining sinus tract. This case highlights how a confounding clinical history, physical examination and initial biopsies may lead to a significant delay in diagnosis. This delay may have resulted in tumour growth and the need for a more extensive partial penectomy than would have occurred had the diagnosis been made more promptly. Finally, this case demonstrates the key diagnostic utility of deep core biopsies of the penis in situations where a cutaneous lesion does not exist.- - - - - - - - - - ranking = 0.023930192955451keywords = sinus (Clic here for more details about this article) |
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