1/31. Morules with biotin-containing optically clear nuclei in colonic tubular adenoma.Morules have been reported in pulmonary endodermal tumors (PET) resembling fetal lung, in thyroid carcinoma, and in endometrial and colonic neoplasms. A morule has biotin-containing optically clear nuclei (OCN) in PET and thyroid carcinoma. biotin-containing OCN have been also reported in endometrial tissue during pregnancy and in endometrioid carcinoma of the ovary, and it has been postulated that morules or OCN develop under the influence of female sex hormones. The authors report here the first case, to their knowledge, of morules with OCN in a colonic adenoma from a 68-year-old man. The colonic polyp consisted of ordinary tubular adenomatous tissue and morules. Many cells in the morules contained OCN. The OCN were immunopositive for biotin and reacted with streptavidin. The neoplastic cells in the morules were immunopositive for oncofetal antigens. serum levels of female sex hormones were within the normal range, and no cells in the adenoma were immunopositive for receptors for progesterone and estrogen. The results indicate that OCN are rich in biotin and that morules may be embryologically immature elements that develop independently of influence by female sex hormones.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
2/31. Inflammatory myofibroblastic tumor with extensive involvement of the bowel in a 7-year-Old child.We present a case of unusual localization of inflammatory fibroblastic tumor in the terminal ileum, cecum, and ascending colon in a 7-year-old child. Segmental resection of the terminal ileum, cecum, and ascending colon with a tumor mass up to 6 cm in diameter was performed. Pathohistological examination of biopsy specimen was performed on routine hematoxylin-eosin sections, as well as immunohistochemically with primary antibodies to CD3, CD20, CD68, factor viii, vimentin, smooth muscle actin, desmin, cytokeratin and S-100 protein, and k and l light chains. The tumor was composed of highly vascularized tissue with interlacing fascicles of elongated spindle cells admixed with plasma cells, histiocytes, lymphocytes, and eosinophils. The diagnosis of inflammatory myofibroblastic tumor was confirmed by immunohistochemistry. Inflammatory myofibroblastic tumor cannot be distinguished clinically from highly malignant neoplasm or some other conditions. Surgical resection and careful pathohistological analysis are needed, and a long-term follow-up is recommended.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
3/31. angiolipoma of the colon with right lower quadrant abdominal pain.BACKGROUND/AIM: An angiolipoma is a common benign neoplasm with a characteristic vascular component that occurs in the subcutaneous tissue and rarely in the gastrointestinal tract. We report on a 69-year-old man with a submucosal angiolipoma in the cecum. methods: This patient was treated with a laparoscopy-assisted ileocecostomy, and a side-to-side anastomosis was performed extracorporeally. RESULTS: A light microscopic study supported the diagnosis of an angiolipoma of the colon. After 5 years of follow-up, the patient has no symptoms or signs of recurrence. CONCLUSION: The colonic angiolipoma was successfully removed using a minimally invasive laparoscopic technique. copyright copyright 1999 S. Karger AG, Basel- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
4/31. neuroendocrine tumors of the gastroenteric canal. Anatomopathological and diagnostic-therapeutic definition. Description of a case with a rare cecal localisation.The authors take the case of a neuroendocrine tumour of the cecum as the starting point for an analysis of the anatomopathological and diagnostic-therapeutic aspects of these neoplasms. Furthermore, the authors underline that neuroendocrine tumours (NET) of the colon represent an extremely rare nosological entity and that they are heterogeneous from a clinical and biochemical point of view, thus making a reliable preoperative diagnosis a problem that is still difficult to resolve today.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
5/31. appendicitis caused by caecal carcinoma--a case report.appendicitis can occur rarely in association with carcinoma of the caecum, particularly in elderly patients. The prognosis for caecal or proximal colonic neoplasm presenting as appendicitis is poor. This is in part due to the association being missed at the initial laparotomy. We report a case of acute appendicitis provoked by an adenocarcinoma of the caecum which obstructed the lumen of appendix in an 84 years old patient by which a simple ileocaecal resection was performed. The difficulties of identifying a small tumor at laparotomy and the implication for optimal treatment are emphasized. It is suggested that a more aggressive attitude should be taken in the pre and postoperative management of any patient over 50 years of age who presents with appendicitis.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
6/31. Goblet cell carcinoid of the appendix: Investigation of the expression of beta-catenin and E-cadherin.Goblet cell carcinoids are rare neoplasms that predominantly occur in the appendix. In this report we present a case of goblet cell carcinoid of the appendix. A 58-year-old male patient complaining of pain in the right lower quadrant was diagnosed with acute appendicitis and underwent an appendectomy. Histological examination of the resected appendix revealed goblet cell carcinoid. Infiltration of tumor cells beyond the appendix was observed and the surgically resected margin was positive for tumor cells. carcinoembryonic antigen (CEA) was diffusely detected by immunohistochemistry, and cytokeratin 20, neuron-specific enolase (NSE), chromogranin a and serotonin were focally observed in the tumor cells. The expression of beta-catenin and E-cadherin was investigated to compare with that of typical rectal carcinoids (n = 3) and colon adenocarcinomas (n = 3). In normal colonic and rectal mucosae, beta-catenin and E-cadherin stained positive on the plasma membrane. In the case reported here, beta-catenin showed a preserved expression on the plasma membrane of goblet cell carcinoid; a pattern similar to typical carcinoids rather than to adenocarcinomas. However, E-cadherin demonstrated a reduced expression on the plasma membrane of the tumor cells. This staining pattern was identical to those both of carcinoids and of adenocarcinomas. These findings suggest the possibility that, in some cases, the adherens junctions of goblet cell carcinoids are similar to those of typical carcinoids rather than to those of adenocarcinomas.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
7/31. Laparoscopically assisted bowel resection for primary mucosa-associated lymphoid tissue lymphoma of the cecum.We present the first report of laparoscopic resection for colorectal mucosa-associated lymphoid tissue (MALT) lymphoma. A 76-year-old man was found to have MALT lymphoma of the cecum during colonoscopy. He underwent a laparoscopically assisted ileocecal resection after admission and was discharged 9 days postoperatively without any complications. Colorectal MALT lymphoma is a rare neoplasm that responds favorably to locally directed therapy, because it tends to remain localized for prolonged periods. Laparoscopic surgery for colorectal MALT lymphoma is considered feasible because it is minimally invasive, making it suitable for treatment of low-grade malignancies, such as MALT lymphoma, which cannot be removed endoscopically.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
8/31. Metastasis to the breast from cecum carcinoma. Case report and review of the literature.Primary malignant tumors of the breast are the most frequently occurring neoplasms in women whereas breast metastases are rare. We report the first case, in literature, of metastasis within the breast resulting from a previous cecum carcinoma. We discuss the case and review the literature.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
9/31. Giant cecal lipoma: a case report.The Authors report a case recently observed of giant lipoma of the cecum. In according to all radiologic diagnostic procedures and for suspicion of colic neoplasm, they have performed a right emicolectomy.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
10/31. Large, vascular cecal mass.A 74-year-old woman had a recent weight loss and history of breast and cutaneous malignancy. Medical evaluation included colonoscopy, which showed a 4 x 3 cm, vascular-appearing mass in the cecum. It was blue-tinged, soft, and easily deformed by pressure. Endoscopic ultrasonography characterized the lesion as a fluid-filled submucosal mass. Because of the suspicion of neoplasm, the patient had exploratory laparotomy and right hemicolectomy. Histopathologic examination revealed a lymphangioma. We review the literature regarding diagnosis and management of colonic lymphangiomas and describe a distinctive case.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
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