1/4. Microascus cinereus (Anamorph scopulariopsis) brain abscess in a bone marrow transplant recipient.We report the first documented case of brain abscess due to the dematiaceous fungus Microascus cinereus, an organism common in soil and stored grain. M. cinereus was isolated from brain abscess material from a bone marrow transplant recipient. The patient responded well to treatment by amphotericin b lipid complex, itraconazole, and a craniotomy but later died from secondary complications caused by graft-versus-host disease.- - - - - - - - - - ranking = 1keywords = complex (Clic here for more details about this article) |
2/4. Cerebral mucormycosis: proton MR spectroscopy and MR imaging.Proton magnetic resonance spectroscopy (MRS) was integrated with magnetic resonance imaging (MRI) in the evaluation of a case of cerebral mucormycosis. MRS showed markedly elevated lactate, depleted N-acetyl aspartate and metabolite resonances attributable to succinate and acetate. The spectroscopy profile is essentially similar to that of bacterial abscess but without the commonly seen resonances of the amino acids valine, leucine and isoleucine. Our extensive literature review did not yield any reports of MRS findings on cerebral mucormycosis. MRS prospectively limited the differential diagnoses given the otherwise nonspecific and complex MR imaging findings in our immunosuppressed patient.- - - - - - - - - - ranking = 1keywords = complex (Clic here for more details about this article) |
3/4. amphotericin b lipid complex for the treatment of recurrent blastomycosis of the brain in a patient previously treated with itraconazole.This is the first reported case of cerebral blastomycosis successfully treated with amphotericin b lipid complex.- - - - - - - - - - ranking = 5keywords = complex (Clic here for more details about this article) |
4/4. major histocompatibility complex and central nervous system involvement by paracoccidioidomycosis.paracoccidioidomycosis (PCM) is a chronic granulomatous infectious disease, whose etiologic agent is the fungus paracoccidioides brasiliensis. The central nervous system (CNS) involvement with paracoccidioidomycosis (NPCM) occurs more frequently than has been admitted in the past. There are some major histocompatibility complex antigen association studies with systemic paracoccidioidomycosis. Some indicate a positive association with hla antigens, but there is no study with the involvement of the CNS. To investigate why not all cases of systemic PCM show the involvement of the CNS and whether genetic factors are involved, we studied 6 patients with NPCM, from the neuroinfection outpatient clinic. The patients were typed for class I and class II antigens by a microlymphocytoxity standard test. The HLA antigen frequencies found in this study in patients with NPCM were not different from the alleles frequencies observed in the Parana population.- - - - - - - - - - ranking = 5keywords = complex (Clic here for more details about this article) |