Cases reported "Cerebrovascular Disorders"

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1/22. Sneddon's syndrome, anticardiolipin antibodies and anticardiolipin cofactor. A case report.

    Sneddon's syndrome is a rare entity characterized by idiopathic livedo reticularis and cerebrovascular lesions. A case of a young woman with livedo reticularis and progressive cerebral arteriopathy is described. Abnormalities of sexual and gonadotropic hormones were present. Anticardiolipin and anticardiolipin-cofactor complex antibodies were not found.
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ranking = 1
keywords = livedo reticularis, reticularis, livedo
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2/22. Sneddon's syndrome: generalized livedo reticularis and cerebrovascular disease. Importance of hemostatic screening.

    We report two cases of Sneddon's syndrome. Both cases had widespread livedo reticularis with repeated cerebrovascular accidents without persistent neurological deficit. In one case, hemostatic examination revealed an imbalance of plasminogen activator-inhibitor values, possibly related to the thrombogenic propensity of the syndrome. Treatment with acetylsalicylic acid led to normalization of hemostatic parameters and resulted in a symptom-free period of more than 10 months. The importance of hemostatic screening in patients with Sneddon's syndrome is discussed.
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ranking = 2.5
keywords = livedo reticularis, reticularis, livedo
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3/22. Sneddon's syndrome and primary antiphospholipid syndrome: a case report.

    The association between livedo reticularis and cerebrovascular accidents is known as Sneddon's syndrome. We describe a case in which Sneddon's syndrome appeared as a clinical manifestation of primary antiphospholipid syndrome.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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4/22. sneddon syndrome presenting with hemicranic attacks: a case report.

    The case of a young woman suffering from a rare cerebrovascular disease associated with livedo reticularis (sneddon syndrome) is reported. Hemicranic attacks were the first symptom detected. The patient had a progressive clinical course of neurologic symptoms. Cerebral CT scan, NMR and cerebral arteriography revealed a progressive cerebral multifarctual feature involving middle-size arteries.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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5/22. Sneddon's syndrome: a rare cause of diffuse vasculopathy. A case report with review of the literature.

    We report a case of Sneddon's syndrome in a 39-year-old woman who developed recurrent cerebral ischaemic events associated with a livedo racemosa. We describe the clinical and radiological features of this rare vasculopathy. We also comment on the nosological place of the disorder and its possible association with antiphospholipid antibodies.
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ranking = 0.045671198809272
keywords = livedo
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6/22. sneddon syndrome: CT, arteriography, and MR imaging.

    We report a rare case of sneddon syndrome, which consists of livedo reticularis and cerebrovascular lesions. The syndrome is characterized by occlusions of medium-sized arteries manifest particularly in the extremities and in the cerebrum. The spectrum of neuroradiological findings in this clinical entity are illustrated and discussed.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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7/22. Sneddon's disease presenting with visual loss and dementia.

    A 51-year-old woman with Sneddon's disease presented with transient right hemifield loss of vision and transient right-sided weakness. Over the preceding decade she had experienced a slow decline in mental function. She also had hypertension, migraine, and a mixed seizure disorder. She had skin changes typical for generalized livedo reticularis but she did not have Raynaud's phenomenon or winter ulcerations. Her disease was not understood until the stroke-related symptoms were associated with the skin abnormalities. We review the neuro-ophthalmic manifestations of Sneddon's disease and add data from our case to the growing body of fact that suggests that Sneddon's disease may be an immunologically mediated vasculopathy.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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8/22. Recurrent stroke and multi-infarct dementia in systemic lupus erythematosus: association with antiphospholipid antibodies.

    Four patients with recurrent stroke and multi-infarct dementia are presented in whom the dementia was progressive and severe. Three of the patients developed the dementia during the course of an illness which was punctuated by repeated episodes of cerebral infarction demonstrated by computed tomographic (CT) scans. The fourth patient presented with an illness dominated by progressive and deteriorating higher mental functions, which culminated in a major stroke 18 months later. Three patients fulfilled the American Rheumatism association (ARA) criteria for the classification of systemic lupus erythematosus, the fourth had a 'lupus-like' disease. All had livedo reticularis, severe migraines, and also demonstrated antibodies to phospholipids. All four patients suffered deep vein thromboses.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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9/22. Anticardiolipin antibodies, livedo reticularis, and major cerebrovascular and renal disease in systemic lupus erythematosus.

    Increased levels of IgG anticardiolipin antibodies (ACA) were found in 23 of 98 patients (23%) with systemic lupus erythematosus. Increased levels of IgM ACA were found less frequently (5%). All four patients with major cerebrovascular events had increased IgG ACA, including the two with highest levels, both of whom were men. Six of nine patients with livedo reticularis had increased IgG ACA. In turn, this clinical feature was associated with cerebrovascular disease in two and renal disease in another six. IgG ACA were not associated with other thromboembolic events, thrombocytopenia, serum IgG, or autoantibodies to Ro(SSA), La(SSB), U1RNP, Sm, or double or single stranded dna.
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ranking = 2.5
keywords = livedo reticularis, reticularis, livedo
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10/22. Sneddon's syndrome.

    A 24 year old woman presented with generalised livedo reticularis and progressive intellectual decline. A CT scan of her head showed multifocal low density areas, consistent with cerebral infarction. cerebral angiography revealed occlusive disease of major vessels, an arteriovenous malformation, and moya-moya type anastomoses. There was no other associated systemic illness. Sneddon's syndrome was the provisional diagnosis. Her older brother had the same skin condition and was also shown to have occlusive cerebrovascular disease. The pathogenesis and natural history of this uncommon disease are highlighted.
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ranking = 0.5
keywords = livedo reticularis, reticularis, livedo
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