Cases reported "Chagas Disease"

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1/4. Chagasic megaesophagus and megacolon diagnosed in childhood and probably caused by vertical transmission.

    Reports on children presenting symptoms compatible with the chronic phase of chagas disease are sporadic. We report a case of a 7-year-old boy who had megaesophagus and megacolon, both of them a consequence of the trypanosomiasis. The etiology was established by means of laboratory and histological features. Based on epidemiological data, the authors concluded that vertical transmission was the most probable route of acquisition. This diagnosis should be considered in children presenting similar complaints, even those living away from endemic areas.
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ranking = 1
keywords = megacolon
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2/4. association of chagasic megacolon and cancer of the colon: case report and review of the literature.

    There are few descriptions of association between chagasic megacolon and colon cancer. We report a case of obstructive abdomen caused by adenocarcinoma of the left colon in chagasic megacolon. A review of the literature revealed 8 cases of this association and, analyzing together the series of findings of cancer in chagasic organomegalies, we found a frequency of 4.8% in megaesophagus and 0.1% in megacolon.
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ranking = 1.4
keywords = megacolon
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3/4. Restorative proctocolectomy for Chagasic megacolon.

    Chagas' disease is endemic in south america, affecting several million people. megacolon, the commonest intestinal manifestation, causes severe constipation and usually requires surgery. We report a case which was treated by restorative proctocolectomy. We believe this to be a useful new technique in the treatment of this condition.
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ranking = 0.8
keywords = megacolon
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4/4. Chagasic megacolon associated with colon cancer.

    Two cases of chagasic megacolon associated with colon cancer are reported. This is the first communication with complete clinical details of this association. Our two cases presented tumors (adenocarcinomas) in a nondilated segment of the transverse colon. The associated tumor lesions were diagnosed by a barium enema. Both patients had a typical clinical epidemiology and history of chagasic megacolon.
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ranking = 1.2
keywords = megacolon
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