1/3. Giant chalazia in the hyperimmunoglobulinemia E (hyper-IgE) syndrome.PURPOSE: To report the occurrence of recurrent multiple giant chalazia in the hyperimmunoglobulin E syndrome (hyper-IgE syndrome or job syndrome). methods: Two patients with hyperimmunoglobulinemia E (>500 IU/ml) had ophthalmologic examination and surgical treatment for chalazia of the eyelids. RESULTS: The hyper-IgE syndrome is a rare immunodeficiency and multisystem disorder characterized by recurrent skin and pulmonary abscesses, connective tissue abnormalities, and elevated levels of serum IgE. In two patients with the hyper-IgE syndrome, multiple giant chalazia were seen in upper and lower eyelids. Despite surgical incision new giant chalazia arose. CONCLUSIONS: Recurrent multiple giant chalazia may occur as an ophthalmic feature of the hyper-IgE syndrome.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/3. "Pseudo-pseudochalazion": giant chalazion mimicking eyelid neoplasm.A 33-year-old man presented with a solid lesion encompassing the entire left upper eyelid. Multiple biopsies revealed lipogranuloma consistent with chalazion. The induration resolved after multiple triamcinolone injections. This is the only case report to our knowledge of a chalazion that involved the entire upper eyelid.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
3/3. chalazion coexisting with dacryolithiasis.A 41-year-old woman presented with a painless hard subcutaneous nodule in the right upper eyelid. The lesion was diagnosed clinically as pilomatricoma and removed surgically. Histological examination disclosed a granulomatous lesion composed mainly of mononuclear cells with a foamy appearance and multinucleated giant cells with some admixture of granulocytes, plasma cells, and lymphoid cells. Lipid droplets and dilated ductal structures containing an eosinophilic fibrillar substance were observed in and around the granulomatous lesion. In addition, an intraductal dacryolith was seen near the granulomatous lesion. We finally diagnosed this case as chalazion; the coexisting dacryolithiasis was considered to be involved in the pathogenesis of chalazion.- - - - - - - - - - ranking = 0.25keywords = giant (Clic here for more details about this article) |