1/31. Migration of intradural epidermoid matrix: embryologic implications.The migratory behavior of acquired cholesteatoma matrices (those arising from the tympanic membrane) has been described previously. This tissue is derived embryologically from the first branchial groove and represents the only migratory epithelium arising from the branchial groove system. If the matrix from a cerebellopontine angle (CPA) epidermoid tumor exhibits migratory behavior similar to that of acquired cholesteatomas, a first branchial groove site of origin for CPA epidermoids would be supported. Intradural CPA epidermoid cells were grown in alpha-minimum essential medium. The cultures were examined daily, and cell mass migration rates were measured. It was observed that intradural epidermoid tumor matrix harvested from the CPA exhibited migration in vitro. Its migratory properties were indistinguishable from those of acquired cholesteatomas, which are embryologically derived from the first branchial groove. These data support the theory that purely intradural epidermoids are derived from cells of the first branchial groove.- - - - - - - - - - ranking = 1keywords = medium (Clic here for more details about this article) |
2/31. Acute mastoiditis and cholesteatoma.Acute coalescent mastoiditis is an uncommon sequela of acute otitis media. It occurs principally in the well-pneumatized temporal bone. The findings of fever, pain, postauricular swelling, and otorrhea are classic. cholesteatoma, on the other hand, being associated with chronic infection, usually occurs in the sclerotic temporal bone. The signs and symptoms are isidious in nature and consist of chronic discharge and hearing loss which result from its mass, bone erosion, and secondary infection. Of 17 consecutive cases of acute mastoiditis over a six-year period, four were atypical because they were complications of chronic otitis media and cholesteatoma, yet they had the physical findings of acute mastoiditis-subperiosteal abscess and purulent otorrhea, plus radiographic evidence of mastoid coalescence.- - - - - - - - - - ranking = 31.300803689949keywords = otitis (Clic here for more details about this article) |
3/31. Mycological and histological investigations in humans with middle ear infections.The aim of our investigations was to characterize fungal colonization of the ear in immunocompetent patients. From 1993 to 2000, 128 patients supposed to suffer from otomycosis were included. Mycological examination conducted by direct microscopy and fungal cultures was performed on 139 specimens. Among these, 115 patients suffered from chronic otitis media with persisting tympanum perforation and otorrhea. A further 13 patients had clinical signs of an otitis externa only. Out of 139 samples, fungi were identified in the auditory canal (n = 54), on the tympanic membrane (n = 5), and in the middle ear (n = 5). Two-thirds were as moulds and one-third yeasts. The dominating species were aspergillus niger and candida parapsilosis. Samples from 15 patients supposed to have mastoiditis or cholesteatoma were examined histologically. Fungal hyphae were observed in the middle ear cavity and/or between horny lamellae of cholesteatoma in four patients. In the middle ear of immunocompetent patients chronic-hyperplastic (polypoid) inflammation was detected with increased production of mucus, which probably promotes colonization by pathogenic fungi in the middle ear as well as in the auditory canal. Invasive fungal growth into the subepithelial connective tissue was not observed.- - - - - - - - - - ranking = 31.300803689949keywords = otitis (Clic here for more details about this article) |
4/31. otitis media and CNS complications.Intracranial complications from otitis media can be quite devastating to the patient if an early diagnosis is not made. patients may develop meningitis, venous sinus thrombosis or cranial nerve palsies, as well as intracranial abscess. The presenting features in such cases may be subtle and include headache, nausea, vomiting, personality changes and signs of increased intracranial pressure as well as focal neurological deficits. A case of intracranial brain abscess is presented in a patient with a history of chronic otitis media with cholesteatoma. Delay in the diagnosis of intracranial complications of otitis media can lead to improper treatment with increased morbidity and mortality. The etiology and treatment of complications affecting the CNS is discussed.- - - - - - - - - - ranking = 46.951205534923keywords = otitis (Clic here for more details about this article) |
5/31. facial nerve paralysis secondary to chronic otitis media without cholesteatoma.Numerous papers have been written on facial nerve paralysis caused by chronic suppurative otitis media. However the authors found none documenting the results of therapy in a series of patients in whom facial nerve dysfunction was caused by chronic otitis media without cholesteatoma. Thus, there is little factual information available to help select a specific therapeutic plan for such cases. Over the past decade, the senior author has managed five cases (6 ears) of chronic suppurative otitis media without cholesteatoma in which facial paresis (4 ears) or paralysis (2 ears) developed 10 days or less before surgery. The chronic otitis media involved the mastoid and middle ear in five cases; and the mastoid, middle ear, and petrous apex in one case. Modified radical mastoidectomy was performed in four ears, tympanomastoidectomy with facial recess exposure in one ear, and complete mastoidectomy with middle cranial fossa petrous apicectomy in one ear. Five patients had complete recovery of facial nerve function (House grade I), and one patient had 90 percent recovery (House grade II). The results provide support for semi-emergent surgery in the management of chronic suppurative otitis media when facial nerve paralysis supervenes.- - - - - - - - - - ranking = 140.85361660477keywords = otitis (Clic here for more details about this article) |
6/31. Mode of growth of acquired cholesteatoma.A histopathological study of acquired cholesteatoma in four temporal bones from two adults and one child is presented. The findings suggest that the cholesteatoma originated from the retraction pockets of the tympanic membrane and there was active growth of the squamous epithelium of the retraction pockets, which may be enhanced in the presence of otitis media.- - - - - - - - - - ranking = 15.650401844974keywords = otitis (Clic here for more details about this article) |
7/31. brain abscess and infections aneurysm of extravascular origin.Acute and chronic ear infection can lead to intracranial involvement. We report on a case in which two typical cerebral complications followed a chronic otitis media. It seemed that there was no causal relationship between brain abscess and meningitis. The meningitis itself was complicated by rupture of an infectious intracranial aneurysm with fatal outcome. We have not been able to find a similar case in the literature. Clinical picture and therapeutic management are discussed.- - - - - - - - - - ranking = 15.650401844974keywords = otitis (Clic here for more details about this article) |
8/31. Subperiosteal and Bezold's abscesses complicating cholesteatoma: a case report.A case of subperiosteal and Bezold's abscesses that occurred in a 60-year-old man with cholesteatoma has been described and the literature reviewed. Bezold's abscess is rarely seen in the current era of antibiotics. The simultaneous occurrence of a subperiosteal abscess in association with cholesteatoma, particularly in an adult, makes this case even more unusual. Although antibiotics have reduced the complications associated with acute otitis media, rare complications still occur and should be recognized by the otolaryngologist.- - - - - - - - - - ranking = 15.650401844974keywords = otitis (Clic here for more details about this article) |
9/31. actinomycosis otitis media.infection of the middle ear and mastoid by actinomycosis is uncommon. We report the 21st case in the English literature. actinomycosis otitis media is characterized by an indolent course but may be fatal. Multiple recurrences after standard antibiotic therapy are common. Effective treatment consists of surgery and penicillin for several months.- - - - - - - - - - ranking = 78.252009224872keywords = otitis (Clic here for more details about this article) |
10/31. Fibrous dysplasia of the temporal bone.A 38-year-old woman with fibrous dysplasia of the entire right half of the mandible and the right temporal bone is presented. She had a unilateral progressive conductive hearing loss and stenosis of the auditory canal complicated by a chronic external otitis, a hidden cholesteatoma, destruction of the ossicles and an impending facial palsy. Surgery was performed to create a new auditory canal, to eradicate the cholesteatoma and to decompress the facial nerve from the surrounding fibrous dysplasia.- - - - - - - - - - ranking = 15.650401844974keywords = otitis (Clic here for more details about this article) |
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