1/6. isospora belli infection in a patient with Hodgkin's disease: report of a case.A 42-year-old woman with a history of documented Hodgkin's disease for 1 year presented with watery diarrhea for 6 months. She developed watery diarrhea following recurrence of the underlying disease and use of herbs. After institution of chemotherapy, watery diarrhea persisted despite remission of the underlying disease. Stool cultures and examinations for several pathogens were negative. Later, oocysts of Isopora belli were identified in the stool. The immunological status was typical of patients with Hodgkin's disease. However, HTLV-1 seropositivity and an intact skin test for delayed hypersensitivity were noted. Institution of co-trimoxazole led to prompt resolution of the gastrointestinal symptoms within the ensuing 24 hours. Later she developed recurrent isosporiasis after chemotherapy for the underlying disease, but institution of co-trimoxazole again resolved the symptoms. She remains on maintenance therapy with co-trimoxazole. isospora belli infection should be considered in opportunistic infections in patients with Hodgkin's disease.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |
2/6. isospora belli in a patient with acquired immunodeficiency syndrome.isospora belli is a cause of protracted diarrhea in immunocompromised patients. acquired immunodeficiency syndrome (AIDS), seen mostly in homosexual men and narcotic addicts, predisposes affected persons to a number of opportunistic infections. As isospora belli has been reported only once in this group, we report isospora belli in an AIDS patient with chronic diarrhea.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |
3/6. Cryptosporidial enteritis and pneumocystis pneumonia in a homosexual man.The case of a 44-year-old homosexual man with cryptosporidial enteritis associated with multiple opportunistic infections and increased T-suppressor cells is reported. This case calls attention to cryptosporidia as the cause of unremitting diarrhea in homosexual men with the syndrome of opportunistic infectious disease associated with acquired immunodeficiency.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |
4/6. cryptosporidiosis in homosexual men.Between April 1982 and June 1983, cryptosporidiosis was diagnosed in six homosexual men. Four patients with the acquired immunodeficiency syndrome had lymphopenia, cutaneous anergy, and profoundly impaired cellular immunity; their cryptosporidiosis was severe, unremitting, and refractory to all therapy. Two patients without other opportunistic infections or Kaposi's sarcoma had moderately impaired cellular immunity but not lymphopenia or anergy; their enteric illness was self-limited. cryptosporidium recently had been recognized as a human pathogen that is transmitted through fecal-oral contamination. The severity of human cryptosporidiosis appears to be determined primarily by immunocompetence of the patient. These six homosexual men, with different degrees of immunologic impairment, had two clinically divergent forms of cryptosporidiosis. Their cases raise questions about human transmission of cryptosporidium and the prognostic significance of this disease in patients who are at high risk for developing the acquired immunodeficiency syndrome.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |
5/6. Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient.A 39-year-old man with severe bullous pemphigoid developed overwhelming diarrhea after 5 weeks' treatment with 150 mg of cyclophosphamide and 60 mg of prednisolone daily. Jejunal and ileal biopsies showed severe mucosal injury and tiny 2- to 4-mu organisms on the epithelial surfaces. Similar organisms were seen in smears of jejunal fluid. Electron microscopic examination of jejunal biopsies showed these spherical bodies to be trophozoites, schizonts, microgametocytes, and macrogametocytes typical of the genus cryptosporidium. diarrhea resolved 2 weeks after discontinuation of cyclophosphamide and coincided with disappearance of Cryptosporidia from the jejunal biopsies. immunosuppression may have predisposed this patient to cryptosporidial diarrhea. cryptosporidiosis is another infection which can be diagnosed by small bowel biopsy. When immunosuppressed patients develop severe diarrhea, opportunistic infection with this and other organisms should be considered as the possible cause.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |
6/6. Human isosporiasis in an AIDS patient--report of first case in malaysia.An AIDS patient with multiple opportunistic infections (candida, pneumocystis carinii and isospora belli) was identified at the University Hospital, Kuala Lumpur. The patient presented with profuse diarrhoea associated with lethargy, anorexia and weight loss. Routine stool examination showed isospora belli oocysts. The infection responded to treatment with trimethroprim-sulfamethoxazole but relapse occurred 8 weeks later. This represents the first documented case of isosporiasis to occur in an AIDS patient in malaysia.- - - - - - - - - - ranking = 1keywords = opportunistic infection (Clic here for more details about this article) |