1/21. Necrotizing and giant cell granulomatous phlebitis of caecum and ascending colon.A distinctive form of necrotizing and granulomatous phlebitis of a segment of large intestine is described in a previously healthy 36-year-old woman who presented with sudden severe abdominal pain and diarrhoea. At operation the caecum and ascending colon were oedematous and inflamed and right hemicolectomy was performed. Microscopically there was striking involvement of veins in all coats of the bowel ranging from recent fibrinoid necrosis of the whole vessel wall in the case of the caecum, to more chronic giant cell granulomas in parts of the vessel wall with partial or complete occlusion of the lumen in ascending colon. Arteries and lymphatics were entirely spared of these changes. The aitiology of this condition has not been elucidated but the histological appearances and site of involvement suggest an immunological reaction to material absorbed from the bowel. No evidence of food or other allergies or of infection has been obtained. The patient remains symptom free after 18 months. This form of phlebitis does not appear to have been previously described.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/21. Vasopressin control of massive hemorrhage in chronic ulcerative colitis.A case of a massive colonic hemorrhage in nontoxic, quiescent ulcerative colitis is described. The source of active colonic bleeding was primarily defined with selective superior mesenteric arteriography and was completely controlled with transcatheter vasopressin infusion. A suubsequent elective segmental distal transverse and descending colectomy revealed chronic ulcerative colitis; localized marked inflammatory giant pseudopolyp formation near the splenic flexure was responsible for the bleeding.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
3/21. giant cell arteritis localized to the colon associated with Crohn's disease.AIMS: Intestinal vasculitis is uncommon and usually accompanies systemic vasculitis. Although intestinal vascular changes including vasculitis have been studied intensively, and are found regularly in Crohn's disease, giant cell arteritis is distinctly unusual. We describe a case of giant cell arteritis localized to the colon of an 18-year-old girl suffering from Crohn's disease. methods and RESULTS: After three years of medical treatment, the patient underwent a proctocolectomy. The medium-sized arteries of the mesocolon demonstrated striking changes characterized by intimal fibrous thickening and an inflammatory infiltrate with giant cells, most predominant at the intima-media junction. epithelioid cells and sarcoid-like granulomas were not observed. The internal elastic lamina was fragmented. Neither clinical symptoms nor laboratory findings showed evidence of systemic vasculitis. Neither the chest CT scan nor the echo-Doppler of the temporal arteries, supra-aortic and abdominal vessels revealed any abnormality. CONCLUSIONS: This case illustrates an extremely rare feature in the spectrum of vascular lesions in Crohn's disease which have to be differentiated from temporal and Takayasu's arteritis.- - - - - - - - - - ranking = 0.6keywords = giant (Clic here for more details about this article) |
4/21. Huge cystic duplication of the ascending colon in adult.Duplications of alimentary tract are uncommon congenital anomalies that are usually identified during the pediatric age. However, a minority of cases remain unsuspected until adulthood. They may be cystic or tubular in appearance and characteristically arise from the mesenteric border of the intestine. This paper reports a 37-year-old male with a huge cystic duplication of the ascending colon. In facing such a huge abdominal cystic tumor, differential diagnoses including duplication cyst, mesenteric cyst, choledochal cyst, giant diverticulum, and cystic tumor of the pancreas should be considered. Computerized tomography is a good tool for delineating the relationship between the tumor and peripheral structures. Surgery not only provides treatment but also final pathological diagnosis. Complete resection of a colonic duplication is necessary because of potential malignant change of the lesion.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
5/21. Giant hamartoma of the ascending colon in an adult with ulcerative colitis.We report an unusual case of giant colonic hamartoma in a 50-yr-old man with ulcerative colitis. The clinical, endoscopic, and histological aspects of this case are discussed. In addition, the possible pathogenesis of colonic hamartoma is reviewed and related to our patient with ulcerative colitis.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
6/21. Peridiverticular colonic hyaline rings (pulse granulomas): report of two cases associated with perforated diverticula.Hyaline ring (pulse granuloma) is a rare benign lesion of the oral cavity soft tissues characterized by round or oval structures with scalloped borders composed by a collagenous matrix variable associated with inflammatory and foreign bogy giant cells. Vegetable fragments are variably identified. Whereas most cases occur in the oral cavity, it has also been described in other sites such as the lung and rectum. It is thought by most to represent a reaction to foreign materials. We report two incidentally discovered cases of colonic hyaline rings associated with perforated diverticulitis. Vegetable residues were seen in both cases.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
7/21. adult descending colocolic intussusception caused by a large lipoma.adult intussusception is uncommon and varies considerably from the more common occurrence of this disorder in infants and children. Although lipoma represents the most common benign tumor of the colon, it is a relatively rare cause of gastrointestinal symptoms. A rare case of adult intussusception of the descending colon caused by a giant lipoma is presented and discussed.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
8/21. A giant colonic hamartoma and multiple colonic hamartomatous polyps in a middle-aged man.Colonic hamartomas are rare polypoid lesions. We report an unusual case of multiple colonic hamartomatous polyps, including a giant hamartoma, unrelated to hereditary or familial polyposis syndromes, in a 48-year-old man. The diameter of the largest polyp was 9.5 cm, and endoscopy revealed that the lesion caused colonic obstruction. The clinical, endoscopic and histological aspects of this case are discussed.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
9/21. Giant colonic mucocele following palliative surgery for recurrent squamous cell carcinoma of the cervix.We report an unusual complication following palliative surgery in a patient with carcinomatosis peritonei from recurrent squamous cell carcinoma of the cervix. At surgery the ascending colon was bypassed and isolated. Eight months later the patient presented with a giant mucocele. We believe this to be the first reported case in the gynecologic literature. This complication could have been prevented by adhering to the standard surgical management of fashioning a mucous fistula.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
10/21. Giant inflammatory polyps associated with idiopathic inflammatory bowel disease. An ultrastructural study of five cases.Five cases of giant inflammatory polyps associated with idiopathic inflammatory bowel disease are reported. polyps produced intestinal obstruction in three cases; consequently, surgery was performed. In a further two cases, intestinal bleeding was improved by endoscopic polypectomy. Electron microscopy showed fibroblasts, myofibroblasts, mast cells, lymphocytes, collagen fibers, capillaries, and venules. Remnants of the original mucosal epithelial cells, smooth muscle cells, and hypertrophic autonomous nerve plexuses were noted. nerve fibers were interwoven with the matrix of the polyps. mast cells were closely linked with vessels, nerves, and collagen fibers. They may have an important role in the excessive granulation, angiogenesis, and fibrotic process in giant inflammatory polyps.- - - - - - - - - - ranking = 0.4keywords = giant (Clic here for more details about this article) |
| | Next -> |