1/226. Beneficial treatment of patients with advanced cancer using a newcastle disease virus vaccine (MTH-68/H).newcastle disease virus Vaccine (MTH-68/H) was administered to patients suffering from advanced neoplastic diseases after non-efficient tumor-destructive treatment. case reports of selected patients suggest promising effects of this treatment. A prospectively-randomized clinical study (phase III; in accordance with Good Clinical Practice, GCP) was proposed to confirm these results and is currently under consideration.- - - - - - - - - - ranking = 1keywords = cancer (Clic here for more details about this article) |
2/226. Colorectal cancer recurrence during pregnancy--unique and poorly understood clinical entity: report of a case.The detection of primary or recurrent colorectal cancer during pregnancy is a rare event. early diagnosis is difficult, because symptoms are often attributed to pregnancy. Here we describe a case of recurrent adenocarcinoma of the colon in a 23-year-old pregnant patient. The relationship between various hormonal and immunological changes of pregnancy and colorectal cancer is discussed.- - - - - - - - - - ranking = 1.5keywords = cancer (Clic here for more details about this article) |
3/226. Fecal occult blood tests in occult gastrointestinal bleeding.Occult gastrointestinal bleeding is diagnosed by using one of the commercially available fecal occult blood tests (FOBTs). guaiac-based slide tests are most frequently used, although the more specific immunochemical methods are promising. The guaiac tests are inexpensive, nonspecific, qualitative measures of stool blood, and their use requires dietary and drug restrictions. Clinicians need to be aware of the causes of false-positive and false-negative test results. Although specific for the presence of human blood, immunochemical tests are more expensive and tend to react also to physiological quantities of blood in fecal specimens. Whichever test is chosen, it must be processed and read correctly. Annual FOBT screening for colorectal cancer, combined with periodic flexible sigmoidoscopy, is a cost-effective method of detecting early, curable colorectal cancer.- - - - - - - - - - ranking = 0.5keywords = cancer (Clic here for more details about this article) |
4/226. Colorectal cancer: genetics and screening.Colorectal cancer is a common disease in the western world. Most, if not all, colorectal cancers develop from previously benign adenomas. There are a number of genetic abnormalities including mutations in oncogenes and tumor suppressor genes which either present as a germline, or acquired defects lead to the development of colorectal cancer. Two well-defined hereditary colorectal cancer syndromes exist, hereditary nonpolyposis colorectal cancer syndrome and familial adenomatous polyposis coli, for which genetic testing is possible and advised. Guidelines for screening for colorectal cancer in average, moderate, and high risk patients are available from the american cancer society and were updated in 1997. The American Society of Clinical Oncology has published guidelines for genetic testing in a variety of cancers including colorectal cancer.- - - - - - - - - - ranking = 3keywords = cancer (Clic here for more details about this article) |
5/226. Colorectal cancer in adolescents.Colorectal cancer, one of the most common malignancies among adults, is rare in adolescence. This low incidence coupled with non-specific symptoms and aggressive natural history leads to a poorer prognosis than in reported adult series. This article describes two cases of colorectal cancer in adolescents and reviews the literature regarding this rare condition. Earlier diagnosis and a greater understanding of the natural history may lead to improved treatment with concomitant improvements in survival.- - - - - - - - - - ranking = 1.5keywords = cancer (Clic here for more details about this article) |
6/226. Colorectal cancer complicating ulcerative colitis: an institutional series.Ulcerative colitis predisposes to colorectal cancer: the risk increases along with disease duration and extension. Also some subsets of patients are at increased risk, namely patients with early onset of colitis, and patients with primary sclerosing cholangitis. Cancer complicating ulcerative colitis affects evenly all the colon, and is not located more frequently in the rectum and in the sigmoid colon, as well as the sporadic counterpart. Multiple cancers and cancers associated with high grade dysplasia are not infrequent in ulcerative colitis; for this reason, and for controlling the colitis, the treatment of choice is total colectomy, with or without colostomy. The prognosis of cancer complicating ulcerative colitis is similar to the sporadic counterpart. The Authors present a colon cancers series as a complication of colitis occurred at Regina Elena Cancer Institute of Rome, italy, over the period 1975-1998.- - - - - - - - - - ranking = 2.25keywords = cancer (Clic here for more details about this article) |
7/226. Transanal endoscopic microsurgery for T1 rectal cancer in patients with synchronous colorectal cancer.We treated T1 rectal cancer in three patients with synchronous colorectal cancer by transanal endoscopic microsurgery (TEM) before performing a radical operation for the second lesion. On pathological examination, all rectal specimens resected by TEM showed cancer invasion within the submucosal layer, while the margins of the specimen were completely free of cancerous tissue. Few complications were encountered with either the TEM for the rectal lesions or the succeeding radical operation for the second lesions. When patients present with synchronous colorectal cancer, including T1 rectal cancer, local excision of the rectal lesion via TEM can help to improve the patient's quality of life without affecting the curability of the disease.- - - - - - - - - - ranking = 3.5keywords = cancer (Clic here for more details about this article) |
8/226. Left extended hemihepatectomy with preservation of large inferior right hepatic vein: a case report.For hepatic function to be preserved after an extended hemihepatectomy adequate venous drainage of the remaining liver is required. Most metastases close to the confluence of the superior hepatic veins are considered unresectable because hepatic venous outflow after resection would be compromised. In 10-25% of people, the inferior right hepatic vein is of large calibre. Thus the superior hepatic veins may be sacrificed and hepatic function preserved if a large inferior right hepatic vein is present. A patient with involvement of segments 2, 4 and 8 by metastatic colorectal cancer is presented. This patient had a large inferior right hepatic vein, and so was able to undergo an extended left hemihepatectomy with ligation of all superior hepatic veins. Subsequent quality of life was maintained. This case illustrates that an 'unresectable' hepatic lesion can be actually resectable if an alternative venous drainage is present. A pre-operative search for a prominent inferior right hepatic vein by ultrasound, computerised tomography, or even magnetic resonance imaging should be considered in these cases.- - - - - - - - - - ranking = 0.25keywords = cancer (Clic here for more details about this article) |
9/226. Oxaliplatin-induced haemolytic anaemia.A case of haemolytic anaemia after therapy with oxaliplatin, an anticancer chemotherapeutic agent, was investigated. Haemolytic anaemia has been associated with cisplatin and carboplatin, two related drugs, but not with oxaliplatin.- - - - - - - - - - ranking = 0.25keywords = cancer (Clic here for more details about this article) |
10/226. Anastomotic recurrence due to tumor implantation using the double stapling technique.The double stapling technique is indispensable in low anterior resection for colorectal cancer. However, to prevent local recurrences due to the driving of cancer cells into the anastomosis. Intraluminal lavage should be performed.- - - - - - - - - - ranking = 0.5keywords = cancer (Clic here for more details about this article) |
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