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1/14. Endemic babesiosis in another eastern state: new jersey.

    In the united states, most reported cases of babesiosis have been caused by babesia microti and acquired in the northeast. Although three cases of babesiosis acquired in new jersey were recently described by others, babesiosis has not been widely known to be endemic in new jersey. We describe a case of babesiosis acquired in new jersey in 1999 in an otherwise healthy 53-year-old woman who developed life-threatening disease. We also provide composite data on 40 cases of babesiosis acquired from 1993 through 2001 in new jersey. The 40 cases include the one we describe, the three cases previously described, and 36 other cases reported to public health agencies. The 40 cases were acquired in eight (38.1%) of the 21 counties in the state. babesiosis, a potentially serious zoonosis, is endemic in new jersey and should be considered in the differential diagnosis of patients with fever and hemolytic anemia, particularly in the spring, summer, and early fall.
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keywords = fever
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2/14. severe acute respiratory syndrome (SARS) and coronavirus testing--united states, 2003.

    CDC and the world health organization (WHO) are continuing to investigate the multicountry outbreak of severe acute respiratory syndrome (SARS). infection with a novel coronavirus has been implicated as a possible cause of SARS. This report updates information on U.S. residents with SARS and summarizes the clinical histories of the five U.S. residents identified as of April 9, 2003, who have both suspected SARS and laboratory evidence of infection with a novel coronavirus.
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ranking = 3.2146228282981
keywords = virus
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3/14. Human rabies: a reemerging disease in costa rica?

    Two human rabies cases caused by a bat-associated virus variant were identified in September 2001 in costa rica, after a 31-year absence of the disease in humans. Both patients lived in a rural area where cattle had a high risk for bat bites, but neither person had a definitive history of being bitten by a rabid animal. Characterization of the rabies viruses from the patients showed that the reservoir was the hematophagous Vampire Bat, Desmodus rotundus, and that a sick cat was the vector.
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ranking = 1.071540942766
keywords = virus
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4/14. severe acute respiratory syndrome--singapore, 2003.

    The singapore Ministry of Health (MOH), with assistance from the world health organization (WHO), has been investigating an outbreak of severe acute respiratory syndrome (SARS). This is a novel condition caused by the SARS-associated coronavirus (SARS-CoV) and is characterized by both an atypical pneumonia and efficient nosocomial transmission. This report summarizes epidemiologic features of this outbreak in singapore, including the influence of super spreaders and the national prevention and control strategy.
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ranking = 0.53577047138302
keywords = virus
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5/14. Reemerging leptospirosis, california.

    leptospirosis is a reemerging infectious disease in california. leptospirosis is the most widespread zoonosis throughout the world, though it is infrequently diagnosed in the continental united states. From 1982 to 2001, most reported california cases occurred in previously healthy young adult white men after recreational exposures to contaminated freshwater. We report five recent cases of human leptospirosis acquired in california, including the first documented common-source outbreak of human leptospirosis acquired in this state, and describe the subsequent environmental investigation. Salient features in the california cases include high fever with uniform renal impairment and mild hepatitis. Because leptospirosis can progress rapidly if untreated, this reemerging infection deserves consideration in febrile patients with a history of recreational freshwater exposure, even in states with a low reported incidence of infection.
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keywords = fever
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6/14. Human metapneumovirus-associated atypical pneumonia and SARS.

    Acute pneumonia developed in a previously healthy man during the outbreak of severe acute respiratory syndrome (SARS) in southern china in March 2003. Antibiotic treatment was ineffective, and he died 8 days after illness onset. Human metapneumovirus was isolated from lung tissue. No other pathogen was found. Other etiologic agents should thus be sought in apparent SARS cases when coronavirus infection cannot be confirmed.
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keywords = virus
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7/14. Case report: brucellosis: a re-emerging disease in thailand.

    brucellosis is a zoonotic disease prevalent in many countries, but it has been reported only once in thailand, 36 years ago. We describe here two consecutive cases of brucellosis in Bangkok, thailand. Both cases presented with prolonged fever and weight loss. blood cultures taken from 2 patients yielded brucella melitensis. The slide agglutination test of blood samples were also positive, with a titer of 1:64 for antibodies to Brucella. The first patient responded to a combination of doxycycline, gentamicin, and ciprofloxacin; the other responded to doxycycline and rifampicin. brucellosis is a potential public health threat, therefore, preventive measures should be actively implemented. This clinical syndrome should be included in the differential diagnosis of patients presenting with prolonged fever, particularly those with contact to animals which could serve as reservoirs.
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keywords = fever
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8/14. monkeypox: a review of the history and emergence in the Western hemisphere.

    A mysterious disease was reported on May 24, 2003, when the wisconsin Division of public health (DPH) received notice of a 3-year-old girl who had been hospitalized in central wisconsin with cellulites and fever after being bitten by a prairie dog on May 13. The laboratory isolated a gram-negative bacillus, raising concerns that it might be tularemia or plague; ultimately, it was identified as an acinetobacter species and was considered to be a contaminant. Because no other such cases were reported at the time, the case was thought to be merely an isolated event. However, within two weeks, on June 2, 2003, evidence of a much wider scenario began to emerge. On that date, the wisconsin DPH received notice from the Marshfield Laboratory that the mother of the first patient had become ill on May 26 and that electron-microscopic evidence of a poxvirus was found in a skin lesion. On that same day, another report, this time from the Milwaukee Health Department, of a strange illness was received at the DPH and described the case of a meat inspector who resided in southeastern wisconsin and also was a distributor of exotic animals. By July 30, 2003, 72 confirmed or suspected cases of monkeypox had been reported in wisconsin, illinois, and indiana and represented a large outbreak. The peak in the onset of illness occurred between May 29 and June 9, 2003, and no further cases of illness have been reported in humans since June 22, 2003. Traceback investigations from the child and other patients followed the route of introduction of monkeypox into wisconsin to a distributor in illinois, who had received a shipment of exotic animals imported into the united states through texas from ghana, West africa.
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ranking = 1.535770471383
keywords = fever, virus
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9/14. west nile virus encephalitis: an emerging disease in renal transplant recipients.

    west nile virus (WNV) has emerged as an important cause of several outbreaks of febrile illness and encephalitis in north america over the past few years. The most common manifestation in symptomatic patients is a transient febrile illness. Neuroinvasive disease, that can be fatal, occurs most often in elderly and immunocompromised hosts. The role of this virus as a cause of meninoencephalitis in organ transplant recipients is becoming better recognized. We describe herein the clinical course of two renal allograft recipients who developed WNV encephalitis. One patient developed status epilepticus and eventually died, while the other had a full recovery. In both cases, the diagnosis was confirmed by detection of WNV-specific IgM in CSF or serum, with a delayed antibody response in one patient. This viral infection should be considered in all renal transplant recipients who present with a febrile illness associated with neurological symptoms.
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ranking = 3.2146228282981
keywords = virus
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10/14. Invasive amebiasis as an emerging parasitic disease in patients with human immunodeficiency virus type 1 infection in taiwan.

    BACKGROUND: Whether risk of invasive amebiasis due to entamoeba histolytica is higher among human immunodeficiency virus (hiv)-infected persons than uninfected persons remains unclear, although intestinal colonization by Entamoeba dispar is common among men who have sex with men. Our objective was to determine the prevalence of invasive amebiasis and intestinal colonization by E histolytica and E dispar in hiv-infected persons and uninfected controls. methods: We assessed the prevalence of invasive amebiasis by case review of 951 hiv-infected persons and by serologic studies of 634 of the 951 hiv-infected persons, 429 uninfected controls with gastrointestinal symptoms, and 178 uninfected healthy controls using indirect hemagglutination antibody assay. We assessed the rate of intestinal colonization by E histolytica and E dispar by fecal antigen and polymerase chain reaction tests in 332 asymptomatic hiv-infected persons and 144 of the 178 uninfected healthy controls. RESULTS: Forty-nine (5.2%) of 951 hiv-infected persons had 51 episodes of invasive amebiasis. A high indirect hemagglutination antibody titer was detected in 39 (6.2%) of 634 hiv-infected persons compared with 10 (2.3%) of 429 uninfected controls with gastrointestinal symptoms and 0 of 178 uninfected healthy controls (P<.001). Stool specimens from 40 (12.1%) of 332 hiv-infected persons and 2 (1.4%) of 144 uninfected healthy controls were positive for E histolytica or E dispar antigen (P<.001). Ten (25.0%) of the 40 antigen-positive stool specimens from hiv-infected persons contained E histolytica. CONCLUSION: persons infected with hiv in taiwan are at increased risk for invasive amebiasis and exhibit a relatively high frequency of elevated antibody titers and intestinal colonization with E histolytica.
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ranking = 2.6788523569151
keywords = virus
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