1/15. Facial dermatitis, contact urticaria, rhinoconjunctivitis, and asthma induced by potato.BACKGROUND: Potato contains multiple heat-labile proteins which can induce immediate hypersensitivity reactions. Rhino-conjunctivitis, asthma, contact urticaria and protein contact dermatitis have been described in association with potato exposure. OBJECTIVE: A patient with possible airborne facial dermatitis to potato is described. RESULTS: A middle-aged atopic housewife with pre-existent atopic dermatitis suffered from rhino-conjunctivitis, asthma, and contact urticaria when pealing raw potatoes, but her main complaint was intense, treatment-resistant dermatitis of the face. The investigations showed a positive prick test, a positive patch test, and positive specific serum IgE to raw potato. Potato avoidance led not only to the resolution of the immediate symptoms, but also of the facial dermatitis, suggesting she had dermatitis due to this vegetable. CONCLUSIONS: Potato may induce contact dermatitis with positive immediate and delayed hypersensitivity tests.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
2/15. Contact dermatitis.BACKGROUND: Anatomically, the eyelid can be divided microscopically into (1) skin, which is made up of epidermis and dermis; (2) submucosa (3) muscular layer; (4) submuscular layer (dense connective tissue); (5) fibrous layer; and (6) palpebral conjunctiva. The thin nature of the eyelid makes it susceptible to inflammation resulting from allergy. Minimum levels of irritants contacting the adnexal area can penetrate the skin to initiate the allergic cascade. Allergic reactions that involve the eye may begin via contact to the skin, but often involve the conjunctiva. eczema is the general term that describes the superficial inflammatory process involving the epidermis. Contact eczema is characterized by varying elements of epidermal erythema, papules, and vesicles. Allergic dermatoconjunctivitis connotes involvement of both the skin and conjunctiva. CASE REPORT: A 24-year-old man came to the clinic with a red, swollen left eye. Based on the history, the constellation of signs and symptoms (lack of diffuse or focal pain, presence of periorbital and conjunctival edema, absence of fever), and failed resolution after treatment with injectable antibiotics, the diagnosis of type IV delayed hypersensitivity reaction secondary to toxic/chemical exposure was made. Speedy resolution was accomplished using a sequenced therapy, which included oral antihistamines, topical cycloplegics, topical antibiotics, topical steroids, and palliative therapies. CONCLUSION: Optometrists should be familiar with the signs and symptoms of contact eczema and allergic dermatoconjunctivitis. Treatment includes management of the skin and adnexae, as well as the ocular manifestations.- - - - - - - - - - ranking = 0.36363636363636keywords = dermatitis (Clic here for more details about this article) |
3/15. Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations.PURPOSE: Atopic dermatitis is a relatively common hereditary dermatologic condition. Ocular sequellae are commonly seen in this disorder and may include involvement of both the anterior and posterior segments of the eye. Clinical symptoms and presentation may vary, as well as visual prognosis. METHOD: A 48-year-old black woman came to us with a sudden exacerbation of atopic disease with ocular complications-most notably, the classic "shield-like" anterior subcapsular cataract seen in patients with this disease. Extensive diagnostic and management considerations specific to this disorder are highlighted. RESULTS: A careful history and clinical examination will help direct appropriate diagnosis and management in this population. Although chronic in nature, acute exacerbations of the disease may require specific management. Proposed pathophysiologic mechanisms, including new aspects of treatment, are discussed. CONCLUSION: Ocular manifestations of atopic disease may be visually debilitating. Therefore, specific consideration relating to clinical course, effective diagnosis, and medical and surgical management of this disorder are discussed.- - - - - - - - - - ranking = 0.45454545454545keywords = dermatitis (Clic here for more details about this article) |
4/15. Allergic contact dermatitis to latanoprost.An 85-year-old male with glaucoma presented with a 1-1/2 year history of tearing; red eyes; and pruritic, edematous, eczematous eyelids. Treatment for presumed ocular rosacea and seborrhea was unhelpful. Patch testing to our standard 64 antigens yielded a positive reaction to Balsam of peru. Notably, benzalkonium chloride, thimerosal, and other preservatives elicited negative reactions. Repeat open application testing elicited positive results to Xalatan (latanoprost) 0.005% ophthalmic solution (Pharmacia & Upjohn, Kalamazoo, MI). A second session of patch tests to 10 personal products, in addition to Xalatan 0.005% solution and the Xalatan vehicle (provided by the manufacturer), elicited a strong positive reaction only to the full preparation of Xalatan 0.005% solution. This report describes the first known case of ACD to latanoprost, a new prostaglandin analog that is widely prescribed for treatment of glaucoma.- - - - - - - - - - ranking = 0.36363636363636keywords = dermatitis (Clic here for more details about this article) |
5/15. Dentist's occupational asthma, rhinoconjunctivitis, and allergic contact dermatitis from methacrylates.BACKGROUND: Allergic contact dermatitis (ACD) caused by (meth)acrylates (MA) is common in dental personnel. MAs have also caused asthma and rhinoconjunctivitis, but asthma, rhinoconjunctivitis and ACD caused by MAs in the same patient appears to be very rare. methods: Occupational asthma and rhinoconjunctivitis were diagnosed in a dentist according to patient history, PEF monitoring, and a work-simulated bronchial provocation test. ACD was diagnosed by skin-patch testing with MAs with the occlusive Finn Chamber-technique. RESULTS: The patient's skin-prick test reactions to common environmental allergens and MAs were negative. The total IgE was not elevated. Occupational asthma was diagnosed by a specific inhalation challenge test in which the patient handled liquid dental MAs for 30 min causing a delayed 23% reduction in FEV1. The provocation test also resulted in rhinoconjunctivitis. On patch testing, positive reactions were provoked by several MAs including 2-hydroxyethyl methacrylate (2-HEMA) to which the patient was occupationally exposed. The patient has not been able to continue her work with dental MAs. CONCLUSIONS: A case of occupational asthma, rhinoconjunctivitis and ACD caused by dental acrylate compounds is presented. patients with respiratory hypersensitivity from MAs have to stop working with MAs, whereas patients with ACD from MAs need to avoid direct contact with MAs, but can often continue in their present job if they use no-touch techniques.- - - - - - - - - - ranking = 0.45454545454545keywords = dermatitis (Clic here for more details about this article) |
6/15. Topical tacrolimus treatment of atopic eyelid disease.PURPOSE: To describe the effects of topical tacrolimus treatment of severe atopic eyelid disease. DESIGN: Interventional consecutive case series. methods: A description of clinical findings and therapeutic response for five consecutive adult patients (mean age, 56.2 years; range 44-62) treated with topical tacrolimus for severe atopic eyelid disease at one institution. RESULTS: Five patients with bilateral atopic eyelid disease that was refractory to treatment with topical corticosteroids were treated with tacrolimus 0.03% ointment, applied to the affected eyelid skin of both eyes twice daily. Eyelid induration, erythema, and eczematous changes were substantially improved within 1 to 3 weeks after initiation of topical tacrolimus treatment in all patients. There was an associated decrease in ocular surface irritation and inflammatory signs in each of four patients who also had atopic keratoconjunctivitis. No adverse effect associated with tacrolimus treatment was noted during continued treatment for 5 to 14 months. All patients were able to discontinue longstanding use of topical corticosteroid drugs. CONCLUSIONS: Application of topical tacrolimus on eyelid skin may be effective for treatment of severe atopic dermatitis of the eyelids, and may have secondary benefits for atopic keratoconjunctivitis. Topical tacrolimus may be used for at least 1 year without apparent adverse reaction in some patients, although the rate of adverse reaction cannot be determined from this small series.- - - - - - - - - - ranking = 0.090909090909091keywords = dermatitis (Clic here for more details about this article) |
7/15. Allergic contact dermatitis due to phenylephrine hydrochloride, with an unusual patch test reaction.2-day (2-D) closed patch tests are often used in daily clinical practice and useful for evaluating the cause of allergic contact dermatitis. However, even when 2-D closed patch tests at appropriate concentrations are performed for suspected allergic contact dermatitis based on clinical findings, positive reactions are not always obtained. Therefore, although the use of the allergen again induces similar symptoms, a definite diagnosis cannot be made in some cases. We report a case of allergic contact dermatitis due to phenylephrine hydrochloride in eyedrops, with an unusual patch test reaction. Although the results of the routine 2-D closed patch test were negative, a definite diagnosis could be made by closed scratch-patch test. In addition, long-lasting allergic patch test reactions were observed at the positive scratch-patch test site for about 3 months. We speculated that these unusual results on patch testing in our case were associated with the degree of percutaneous absorption of causative agents. Therefore, even when 2-D closed patch tests are negative, scratch-patch tests may be indicated for patients in whom clinical symptoms continue strongly to suggest contact dermatitis.- - - - - - - - - - ranking = 0.72727272727273keywords = dermatitis (Clic here for more details about this article) |
8/15. Omalizumab: a future innovation for treatment of severe ocular allergy?Conjunctival and corneal manifestations of atopic keratoconjunctivitis (AKC) are chronic, disabling and may be blinding. In common with other allergic diseases, such as asthma and atopic dermatitis, AKC is characterised by an allergen-induced immune response mediated through expression of IgE. The humanised monoclonal IgE antibody Xolair (omalizumab) complexes with free circulating IgE, thereby preventing binding of IgE to FcepsilonRI receptors on immune cells. Omalizumab effectively alleviates the signs and symptoms of asthma. Given the pivotal role of IgE in the allergic cascade, it is hypothesised that omalizumab has potential as an entirely new therapeutic approach to AKC.- - - - - - - - - - ranking = 0.090909090909091keywords = dermatitis (Clic here for more details about this article) |
9/15. Severe allergic keratoconjunctivitis and erythema multiforme after a routine eye examination: discerning the cause.Acute allergic dermatitis of the eyelids with keratoconjunctivitis is associated with a specific triggering factor. Therapy for the acute inflammation can complicate the search for such a factor if the process worsens. We report a case of acute contact dermatitis and keratoconjunctivitis after a routine eye examination to demonstrate the difficulty in evaluating such patients and the role of skin patch testing in determining the cause.- - - - - - - - - - ranking = 0.18181818181818keywords = dermatitis (Clic here for more details about this article) |
10/15. Atopic dermatitis flare provoked by inhalant allergens.We report on 2 patients with atopic dermatitis (AD) exacerbated by inhalant allergens: grass pollens in spring (AD as hay fever equivalent) and nonbiting red midges (chironomides) in pet fish food. These clinical observations confirm the existence of an 'extrinsic', IgE-mediated type of AD in a minority of patients, in which the IgE sensitization against specific allergens plays a causal role for the skin disorder.- - - - - - - - - - ranking = 0.45454545454545keywords = dermatitis (Clic here for more details about this article) |
| | Next -> |