1/10. Surgical resection of giant papillae and autologous conjunctival graft in patients with severe vernal keratoconjunctivitis and giant papillae.PURPOSE: Giant papillae (GP) in patients with vernal keratoconjunctivitis (VKC) refractory to clinical treatment may cause serious corneal complications, such as shield ulcer. We propose a surgical treatment--resection of GP--in conjunction with free autologous conjunctival graft to treat severe cases of VKC with GP. methods: Six eyes of five patients with VKC, characterized by GP and shield ulcer refractory to clinical treatment, underwent surgical resection of GP associated with free autologous conjunctival graft. RESULTS: No recurrence of GP over the graft was observed during follow-up intervals ranging from 9 months to 27 months. Corneal shield ulcers healed during the first week after treatment and did not recur. CONCLUSIONS: patients with refractory VKC and GP associated with corneal shield ulcer may benefit from resection of GP and autologous conjunctival graft.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/10. Bilateral conjunctival mucosa-associated lymphoid tissue lymphoma misdiagnosed as allergic conjunctivitis.PURPOSE: This report aimed to discuss two nearly identical cases of primary conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma mimicking allergic conjunctivitis. methods: Two patients were referred for intractability to conventional treatment of initial diagnoses of allergic conjunctivitis. On ocular examination, normally pigmented, giant papilla-like lesions were found bilaterally in the upper conjunctiva. Excisional biopsies were performed. RESULTS: Histopathologic and immunohistochemical examination of the conjunctival biopsies indicated MALT lymphoma in both patients. The patients subsequently received radiation therapy and achieved complete remission with no evidence of recurrence during follow-up periods of 13 and 11 months. CONCLUSION: Conjunctival low-grade lymphoma may share similar clinical features with allergic conjunctivitis. Ophthalmologists should be concerned that primary conjunctival low-grade malignant lymphoma can be misdiagnosed as allergic conjunctivitis- - - - - - - - - - ranking = 0.125keywords = giant (Clic here for more details about this article) |
3/10. Surgical treatment and desensitization therapy of giant papillary allergic conjunctivitis.We found that three cases of giant papillary conjunctivitis responded well to local specific desensitization therapy and transplantation of the conjunctiva with saphenous vein tissue.- - - - - - - - - - ranking = 0.625keywords = giant (Clic here for more details about this article) |
4/10. Removal of giant vernal papillae by CO2 laser.BACKGROUND: We report our experience in removing giant papillae in cases with severe vernal keratoconjunctivitis using CO2 laser. methods: Five cases with conjunctival giant papillae due to severe vernal keratoconjunctivitis were treated with CO2 laser. All cases were resistant to conventional treatment. In 4 eyes, there was also an associated corneal shield ulcer. RESULTS: In all 5 cases the procedure was uneventful. retreatment was performed in only 2 cases because of recurrence of the papillae. No intra- or postoperative complications were observed. INTERPRETATION: CO2 laser seems to be a safe method for removing conjunctival giant papillae in cases with severe vernal keratoconjunctivitis. It is also a repeatable method that enables a rapid conjunctival and corneal recovery.- - - - - - - - - - ranking = 0.875keywords = giant (Clic here for more details about this article) |
5/10. Rapid healing of vernal shield ulcer after surgical debridement: A case report.PURPOSE: This study was designed to report a patient with a vernal shield ulcer that did not respond to medical therapy but healed in 1 week after surgical debridement of the ulcer base. methods: Case report and literature review. RESULTS: A 12-year-old girl with a history of asthma and eczema was seen with a 5.7- x 5.7-mm corneal epithelial defect in the right eye. Her uncorrected visual acuity was 20/200 OD and 20/70 OS. Slit-lamp examination revealed giant papillae on the tarsal conjunctivae, diffuse punctate epitheliopathy, and a thick mucoid discharge in both eyes. A diagnosis of vernal keratoconjunctivitis both eyes (OU) with a shield ulcer OD was made and prednisolone 1% was started 4 times per day OD. Topical ofloxacin 0.3% 3 times per day and topical cyclosporine 0.05% every 2 hours were added OD 2 days later. On minimal improvement in the epithelial defect in 1 week, surgical debridement of the ulcer base was performed. The epithelial defect healed smoothly in 1 week with an underlying stromal scar and the uncorrected visual acuity improved to 20/70 OD at 1 month and 20/40 at 10 months. CONCLUSION: Corneal shield ulcers and plaques are rare but serious complications of vernal keratoconjunctivitis, which may be unresponsive to standard medical therapy. Surgical debridement is a fast and effective procedure yielding rapid healing of the ulcer and minimizing complications, such as infections.- - - - - - - - - - ranking = 0.125keywords = giant (Clic here for more details about this article) |
6/10. Vernal keratoconjunctivitis presenting unilaterally.A 7-year-old boy had itching, foreign body sensation, and redness in his right eye. Unilateral cobblestone papillae and a shield ulcer were found. Topical antihistamines, mast cell stabilizers, and steroids led to marked improvement. Unilateral vernal keratoconjunctivitis should be included in the differential diagnosis of unilateral giant papillary conjunctivitis.- - - - - - - - - - ranking = 0.125keywords = giant (Clic here for more details about this article) |
7/10. Papillary conjunctivitis induced by an epithelialized corneal foreign body.This report of papillary conjunctivitis induced by a corneal foreign body suggests that papillogenesis may result from physical/mechanical tissue trauma. A case is presented with an epithelialized corneal foreign body in the peripheral cornea during a 9-month period. The overlying corneal epithelial surface was elevated, and corresponding upper tarsal conjunctiva revealed localized, elevated papillae. One month after the foreign body was excised, the papillae resolved. An epithelialized foreign body, elevated cornea, and coincidental papillae support the role of physical trauma for the development of papillae--a feature of the syndrome of contact-lens-associated giant papillary conjunctivitis.- - - - - - - - - - ranking = 0.125keywords = giant (Clic here for more details about this article) |
8/10. Giant papillary conjunctivitis from an exposed prolene suture.We document an example of unilateral giant papillary conjunctivitis (GPC) following division of a fine-gauge prolene suture employed several months earlier to close a cataract incision. Release of surgically induced astigmatism required relaxation of the suture. The conjunctival response abated with removal of the retained suture fragments. The conjunctival reaction was biopsied and shown to be similar histopathologically to that seen in GPC associated with vernal conjunctivitis and contact lens wear.- - - - - - - - - - ranking = 0.125keywords = giant (Clic here for more details about this article) |
9/10. Unusual causes of giant papillary conjunctivitis.We report two unusual causes of giant papillary conjunctivitis (GPC). One patient developed GPC secondary to and elevated filtering bleb. Another patient developed focal GPC secondary to elevated calcific plaques (band keratopathy). The first patient's symptoms improved after treatment with sodium cromolyn drops. GPC resolved in the second patient after superficial keratectomy was performed. These cases represent two unusual causes of GPC and emphasize the role of mechanical trauma as a causative factor.- - - - - - - - - - ranking = 0.625keywords = giant (Clic here for more details about this article) |
10/10. Causative factors in unilateral giant papillary conjunctivitis.Giant papillary conjunctivitis (GPC) is usually a bilateral disease. However, in a small number of cases, GPC can be manifested as a unilateral, or a markedly asymmetrical disease in patients wearing bilateral contact lenses. We reviewed the clinical records of 148 patients with GPC to determine the incidence of unilateral GPC and its causative factors. Specifically, charts were reviewed for data on refractive error, keratometry, lens fit, lens care, lens replacement, and the presence or absence of associated ocular abnormalities (dry eyes, blepharitis, previous injury, or surgery). Fourteen patients with unilateral or markedly asymmetrical disease were identified. overall, no statistically significant difference was found in lens care, refractive error, or keratometric measurements in the affected and unaffected eyes. While not statistically significant, infrequent lens replacement appears to be an important factor in the development of unilateral GPC. Three patients had a history of wearing an older lens in the GPC eye. Two patients were found with unilateral meibomian gland dysfunction involving the affected eye, and one patient had undergone surgery on the affected eye. No causative factor was identified in eight cases.- - - - - - - - - - ranking = 0.5keywords = giant (Clic here for more details about this article) |
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