1/13. Molecular evidence of ocular Epstein-Barr virus infection.Ocular manifestations have been attributed to the Epstein-Barr virus (EBV), largely on the basis of seroepidemiologic data. Two patients who developed conjunctival disease as the presenting feature of EBV infection are reported, each confirmed by in situ hybridization of EBV genome in affected tissue biopsy specimens. Recognition of EBV-induced ocular disease as an initial presentation of clinical EBV infection is important to the practitioner because of the ubiquitous nature of this herpesvirus.- - - - - - - - - - ranking = 1keywords = herpes, ocular (Clic here for more details about this article) |
2/13. Ocular involvement in an outbreak of herpes gladiatorum.An epidemic of herpes simplex virus type 1 occurred in 60 of 175 wrestlers (34%) attending a four-week intensive training camp. Five of these 60 patients (8%) developed ocular involvement that included follicular conjunctivitis, blepharitis, and phlyctenular disease. Cultures of the conjunctiva and eyelid vesicles were positive for herpes simplex virus type 1 in four of the five patients with ocular disease. The viral isolates were compared by restriction-endonuclease analysis, which disclosed that three of the four isolates were the same strain. None of the patients had corneal involvement and there has been no evidence of viral recurrence to date. herpes simplex virus type 1 is a health risk for wrestlers, and ocular infections are part of the clinical spectrum. Prompt diagnosis and appropriate management of the outbreak may reduce the severity of the outbreak transmission.- - - - - - - - - - ranking = 14.552923482443keywords = herpes simplex, simplex, herpes, ocular (Clic here for more details about this article) |
3/13. Adenovirus pneumonia with severe sequelae in an immunocompetent adult.Notable complications from adenovirus pneumonia in healthy adults are rare. We report a well-documented case of adenovirus type 3 infection in a previously well adult woman that resulted in severe pulmonary complications as well as self-limited ocular, hepatic, and gastrointestinal abnormalities.- - - - - - - - - - ranking = 0.09102598111718keywords = ocular (Clic here for more details about this article) |
4/13. Concomitant oculoglandular and ulceroglandular fever due to herpes simplex virus type I.herpes simplex virus is a commonly encountered infectious agent in clinical practice. The syndromes with which it is usually associated are well described and generally easily recognized. This report documents that two uncommon clinical syndromes, ulceroglandular fever and oculoglandular fever, may be caused by this virus. Our patient's case was even more unusual in that both conditions occurred simultaneously.- - - - - - - - - - ranking = 23.441649348834keywords = herpes simplex, simplex, herpes (Clic here for more details about this article) |
5/13. Ocular vaccinia following exposure to a smallpox vaccinee.PURPOSE: To describe the presentation and management of the first identified case of ocular vaccinia infection associated with the current smallpox vaccination program. DESIGN: Case report. methods: vaccinia virus was isolated by cell culture of a conjunctival swab. Direct staining with fluorescein isothiocyanate-labeled vaccinia antibody and polymerase chain reaction testing confirmed the diagnosis. RESULTS: In February 2003, a 26-year-old woman developed right preseptal cellulitis and blepharoconjunctivitis following contact with a vaccinated member of the military. The preseptal cellulitis resolved with antibacterial therapy, and the conjunctival infection was treated successfully with a 14-day course of topical trifluridine and a single dose of intravenous vaccinia immune globulin. CONCLUSIONS: To facilitate rapid diagnosis and appropriate treatment, clinicians must maintain a high index of suspicion for ocular smallpox vaccine-associated adverse reactions in vaccine recipients and their close contacts.- - - - - - - - - - ranking = 0.18205196223436keywords = ocular (Clic here for more details about this article) |
6/13. Diffuse lamellar keratitis and corneal edema associated with viral keratoconjunctivitis 2 years after laser in situ keratomileusis.A 47-year-old woman with a history of laser in situ keratomileusis (LASIK) 2 years previously for myopia and astigmatism, presented with bilateral loss of vision due to diffuse lamellar keratitis (DLK) with corneal edema in the context of a pseudomembranous viral keratoconjunctivitis. After intense and early treatment with topical corticosteroids, the corneal edema and DLK resolved and corneal transparency was achieved with complete restoration of visual acuity. This case shows that DLK may occur associated with a viral pseudomembranous keratoconjunctivitis in patients who have had LASIK. Diffuse lamellar keratitis may present up to 2 years after lamellar surgery, which would indicate that the plane created by the microkeratome at the interface may remain unhealed for at least this period of time. early diagnosis and treatment with topical corticosteroids can achieve complete resolution without visual loss.- - - - - - - - - - ranking = 27.124811747714keywords = keratitis (Clic here for more details about this article) |
7/13. Virus-induced chalazion.PURPOSE: To investigate a viral etiology in certain chalazia. methods: A prospective study over 7.5 years of all newly presenting chalazia associated with diffuse follicular conjunctivitis but without any other aetiological factors. patients were investigated for ocular or systemic infections by history, physical exam, slit-lamp exam, and/or histology of conjunctival biopsy (including transmission electron microscopy). RESULTS: A total of 27 patients developed follicular conjunctivitis without meibomian gland dysfunction, blepharitis, or sexually transmitted diseases. Evidence for a viral aetiology included: recent systemic viral illness (15/27), recent contact with subjects with chalazia or follicular conjunctivitis (5/27), preauricular lymphadenopathy (4/27), viral corneal disease (4/27), or viral particles by ultrastructure (4/4). CONCLUSIONS: Chalazia may be associated with viral conjunctivitis. Intralesional corticosteroids should be considered with great caution for viral-induced chalazia.- - - - - - - - - - ranking = 0.09102598111718keywords = ocular (Clic here for more details about this article) |
8/13. Ocular vaccinia infection in laboratory worker, philadelphia, 2004.We report a case of ocular vaccinia infection in an unvaccinated laboratory worker. The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet. vaccination should continue to be recommended, but laboratories with unvaccinated workers should also implement more stringent biosafety practices.- - - - - - - - - - ranking = 0.09102598111718keywords = ocular (Clic here for more details about this article) |
9/13. Allergy and infections: long-term improvement of vernal keratoconjunctivitis following viral conjunctivitis.PURPOSE: Vernal keratoconjunctivitis (VKC) is a severe, chronic allergic inflammatory disease of the ocular surface poorly responsive to antiallergic treatments and possibly leading to permanent visual impairment. VKC, because of mast cell, eosinophil, and Th2-type inflammation, polyclonal IgE activation, and tissue remodeling, is considered to be a typical Th2- driven disease. Viral infection stimulates a Th1 type immune response, potentially attenuating allergen-induced inflammation. The purpose of this report is to describe the effect of viral keratoconjunctivitis in a patient with VKC. methods: The authors report on a patient with a severe form of VKC, poorly responsive to antiallergic treatments, who developed a viral keratoconjunctivitis. Signs, symptoms, and cytologic findings were recorded during the 5-year follow-up period. RESULTS: The authors observed a prompt and permanent improvement of signs and symptoms of the allergic condition after the viral infection. Conjunctival scraping confirms that the inhibition of the eosinophilic inflammation lasts at least for 5 years. CONCLUSIONS: In this case, the viral infection seemed to induce a clinical recovery of allergic disease, suggesting that an immune deviation induced by Th1-polarizing agents may revert an ongoing Th2 inflammation.- - - - - - - - - - ranking = 0.09102598111718keywords = ocular (Clic here for more details about this article) |
10/13. Diagnosis and management of conjunctival papillomas.Lumps and bumps have been seen on the ocular surface or adnexa of many of our patients. Most of these are readily identified; however, we may occasionally see an unusual "growth" and wonder about its pathological significance. The topic of epithelial neoplastic growths with special emphasis on the subclass of papillomas is reviewed. The question of histopathological significance is raised in a case of epibulbar conjunctival growths. The differential diagnosis, which leads to the definitive diagnosis of viral conjunctival papillomas, is discussed. The management of viral conjunctival papillomas is reviewed.- - - - - - - - - - ranking = 0.09102598111718keywords = ocular (Clic here for more details about this article) |
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