1/10. Surgical treatment of chronic mandibular dislocation--report of a case.Chronic dislocation of the temporomandibular jaw (TMJ) can result from lax joint ligaments and parafunctioning joints; it can also be a consequence of a systemic connective tissue disorder. The authors report a case of hypermobile joint syndrome in combination with mitral valve prolapse. The case was managed by osteosynthesis using modified titanium plate.- - - - - - - - - - ranking = 1keywords = ligament (Clic here for more details about this article) |
2/10. Tuberculous arthritis in the course of connective tissue disease: report of 4 cases.We describe 4 female patients with diverse connective tissue diseases who developed tuberculous arthritis concurrently with their underlying disease, in the absence of lung involvement. Throughout, diagnosis was delayed but later confirmed by detection of mycobacterium tuberculosis in synovial membrane culture. Two patients died of unrelated causes, while the other 2 recovered with chronic joint sequelae. Despite the rarity of this association, M. tuberculosis infection should be considered in the differential diagnosis of chronic mono or oligoarthritis in patients with connective tissue diseases.- - - - - - - - - - ranking = 0.011526501514105keywords = membrane (Clic here for more details about this article) |
3/10. Mucoid degeneration of the anterior cruciate ligament--a report of two cases.We report two cases of mucoid degeneration of the anterior cruciate ligament (ACL). Mucoid degeneration of the ACL is a very rare cause of knee pain. There have been only seven reported cases of mucoid degeneration of the ACL in the English literature. We reviewed previous reports and summarized clinical features and symptoms, including those found in our two cases. MRI is the most useful tool for differentiating mucoid degeneration of the ACL from an intraligamentous ganglion or other lesions in the knee joint. If this disease is considered preoperatively, it can be diagnosed easily based on characteristic findings.- - - - - - - - - - ranking = 6keywords = ligament (Clic here for more details about this article) |
4/10. Necrotizing myopathy with pipestem capillaries, microvascular deposition of the complement membrane attack complex (MAC), and minimal cellular infiltration.Three adult patients, two with undifferentiated connective tissue disease and one with carcinoma, had a distinctive pathologic reaction pattern consisting of necrotizing myopathy, minimal cellular infiltration, and a microangiopathy with thick "pipestem" vessels and microvascular deposits of complement membrane attack complex. Quantitative analysis revealed focal capillary depletion. This pattern represents an immune-mediated microangiopathy and is distinct from that observed in other inflammatory myopathies.- - - - - - - - - - ranking = 0.057632507570527keywords = membrane (Clic here for more details about this article) |
5/10. Circulating antibodies and immune complexes in oral mucosal diseases.This paper reviews the use of measurement of circulating auto-antibodies and antibodies to food proteins, and of circulating immune complexes (CIC) for diagnosis of various systemic diseases with oral involvement. Results of a study of 29 patients suffering from chronic oral mucosal disease, in which such methods were applied are reported. Auto-antibodies against epithelial intercellular substance (AICSA) were found in three patients, two of whom had pemphigus. Only one of the two patients diagnosed as having pemphigoid had circulating antibodies to basement membrane zone (ABMZA). Auto-antibodies to reticulin (IgA-ARA) were found in one patient in whom a diagnosis of coeliac disease (CD) was confirmed by intestinal biopsy. In addition to the patient with CD, another patient had IgA class antibodies against gliadin (IgA-AGA). IgG-AGA were found in five other patients, in one of whom dermatitis herpetiformis (DH) was diagnosed. antibodies to cow's milk (ACMA) were detected in 10 patients and CIC in 4 patients. case reports are given to illustrate the important role of antibody determination coupled with histopathological and immunofluorescence examination of tissue biopsy material in the diagnosis of serious oral disease.- - - - - - - - - - ranking = 0.011526501514105keywords = membrane (Clic here for more details about this article) |
6/10. Unusual case of diffuse connective tissue disease with nodule formations in muscle, lung, kidney and brain.A 9-year-old boy had nodular masses in the left gastrocnemius muscle and lung, right kidney and right frontal area of the brain. Laboratory examinations, including positive anti-nuclear antibody, anti-RNP antibody, RA and CRP, hyper-gamma-globulinemia and accelerated ESR, showed characteristic of diffuse connective tissue disease (DCTD). biopsy specimens were obtained from the thymus and from masses in the left lung and gastrocnemius muscle. The thymus showed hyperplasia, and a mass in the lung showed nonspecific inflammatory reactions such as connective tissue proliferation and cellular infiltration. Biopsied muscle also showed severe connective tissue proliferation, cellular infiltration, variation in fiber size and thickened blood vessel walls. In addition, abnormalities, including thickening of the basement membrane and an almost occluded narrow lumen of capillaries, were found on electron microscopy examination. Steroid administration led to remarkable improvement of the symptoms. These results suggested that DCTD is responsible for these symptoms.- - - - - - - - - - ranking = 0.011526501514105keywords = membrane (Clic here for more details about this article) |
7/10. A direct immunofluorescence study in elastosis perforans serpiginosa.Two cases of elastosis perforans serpiginosa were studied by direct immunofluorescence. In one case, homogeneous deposits of IgM, C3 and C4 on the abnormal elastic fibres in the papillary dermis were demonstrated. In addition, in both cases, along the basement membrane zone, coarse linear deposits of fibrinogen and properdin were observed inside and near the transepidermal channels. Groups of cytoid bodies stained for IgM and occasional weak linear deposits of IgG, IgA, IgM and C3 were also observed. The immune deposits on the abnormal elastic fibres might indicate antigenic alteration and activation of humoral immunological mechanisms in the process of their elimination. The other findings may reflect a non-specific binding by damaged tissue structures.- - - - - - - - - - ranking = 0.011526501514105keywords = membrane (Clic here for more details about this article) |
8/10. Variable clinical presentation of cutis laxa.We present 2 families with 4 individuals suffering from congenital cutis laxa. family A has a single affected male child with developmental delay and ligamentous laxity, making this only the second male of the total 15 patients so far reported with this particular syndrome. family B has 3 affected males, 2 of whom have significant involvement of other systems. Only one of the 4 affected children had very obvious loose skin folds and dependency on this clinical feature alone could result in under-diagnosis of this disease. The clinical features and family pedigree information suggests recessive inheritance in family B but the mode of inheritance in family A is inconclusive.- - - - - - - - - - ranking = 1keywords = ligament (Clic here for more details about this article) |
9/10. oral manifestations of infantile systemic hyalinosis.oral manifestations of infantile systemic hyalinosis in a child of Asian origin are presented. Infantile systemic hyalinosis is a rare fatal condition with probably an autosomal recessive mode of inheritance. The symptoms become apparent soon after birth and death usually occurs before the age of two years. The systemic features are essentially due to widespread deposition of hyaline material in tissues. These include thickening and nodularity of skin, growth failure, joint contractures, osteoporosis, diarrhoea and recurrent infections. The oral changes in the case reported here included thickening of the oral mucosa, extensive overgrowth of gingival tissue, osteoporosis, marked curvature of the dental roots, and replacement of periodontal ligament by hyaline fibrous material. immunohistochemistry revealed widespread presence of Type VI collagen in the connective tissue with particularly intense staining in the hyaline material.- - - - - - - - - - ranking = 1keywords = ligament (Clic here for more details about this article) |
10/10. Multiple arteriovenous malformations in a man with a connective tissue disorder.Multiple arteriovenous malformations in patients with connective tissue disorders are not reported. We describe a man with cutaneous, ligament/articular and vascular features suggestive of a connective tissue disorder and who also has multiple arteriovenous malformations resulting in a high output circulatory state. chest pain due to arteriovenous malformations originating from subclavian vessels has caused considerable morbidity.- - - - - - - - - - ranking = 1keywords = ligament (Clic here for more details about this article) |
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