1/16. Acquired segmental megacolon in an adult patient with cystic fibrosis.cystic fibrosis (CF) is characterized by symptoms related to pulmonary dysfunction and pancreatic insufficiency. constipation, though a frequent complaint of patients with CF, receives less attention. We report a case of acquired segmental megacolon and constipation necessitating surgical colonic resection in an adult patient with CF. The differential diagnosis and possible causes of megacolon in this setting are discussed.- - - - - - - - - - ranking = 1keywords = megacolon (Clic here for more details about this article) |
2/16. Surgical treatment of a sigmoid volvulus associated with megacolon: report of a case.Sigmoid volvulus occurring concomitantly with megacolon is an uncommon cause of bowel obstruction, and various approaches to treatment have been proposed. We report herein a case of sigmoid volvulus with megacolon that was successfully treated by elective surgery following endoscopic reduction during the same hospital stay. A 70-year-old woman was admitted to our hospital with abdominal pain, distension, and severe constipation. physical examination, plain abdominal X-ray, and barium enema confirmed a sigmoid volvulus and further examinations revealed concomitant megacolon. An elective sigmoid colectomy was performed following successful endoscopic decompression. The postoperative course was uneventful and there was no residual colonic dysmotility. Histologically, no aganglionic tissue was observed in the resected specimen.- - - - - - - - - - ranking = 1.1666666666667keywords = megacolon (Clic here for more details about this article) |
3/16. Chronic constipation due to Hirschsprung's disease and desmosis coli in a family.Five members of a family are described, all of whom suffered from chronic constipation and megacolon. Detailed clinical and histologic evaluation of each member revealed that two individuals have histologic evidence of desmosis coli and three have Hirschsprung's disease, one of whom also has desmosis coli. The latter combination has never been described before, either in a family or in a single patient. Genetic studies of the family did not reveal an increase in the number of shared markers for the RET proto-oncogene, suggesting that this previously undescribed familial association is likely not caused by a mutation in the RET gene, but by other genetic abnormalities.- - - - - - - - - - ranking = 0.16666666666667keywords = megacolon (Clic here for more details about this article) |
4/16. Giant fecaloma with idiopathic sigmoid megacolon: report of a case and review of the literature.PURPOSE: fecal impaction is a common condition, and " fecaloma" is an extreme variety of impaction. This is a report of a giant, solitary, and stubborn fecaloma not responding to nonoperative management. A surgical intervention for uncomplicated fecal impaction is rarely needed and reported in the literature. METHOD: A 39-year-old male patient with constipation presented with a firm, mobile, abdominal mass of six-months duration. Investigations revealed an isolated, giant fecaloma in a redundant sigmoid megacolon. After all the conservative measures were unsuccessful in evacuating the stubborn impaction, he was treated by sigmoid colectomy and primary anastomosis. CONCLUSION: A timely surgical intervention in recalcitrant fecal impactions may prevent possible stercoral ulcer perforation with a high mortality.- - - - - - - - - - ranking = 0.83333333333333keywords = megacolon (Clic here for more details about this article) |
5/16. adult Hirschsprung's disease diagnosed during forensic autopsy.We report a case of fatal Hirschsprung's disease (HD) discovered at autopsy. A 20-year-old man collapsed at home. Emergency medical personnel found him in cardiac arrest and all resuscitative efforts failed. He had a past history of chronic constipation since infancy. Forensic autopsy revealed a megacolon full of gas and stools. Microscopic examination showed absence of ganglion cells in a short segment of the rectum and enterocolitis in the left and transverse colon. HD is rarely described in adults. In many cases, patients complained of constipation since infancy but the affection remained misdiagnosed. The relative good tolerance of the disease is usually due to a short aganglionic bowel segment. enterocolitis is a frequent and severe complication of HD in children but is rarely described in adults. This case suggests the importance of HD diagnosis in childhood in order to avoid fatal complications with forensic consequences.- - - - - - - - - - ranking = 0.16666666666667keywords = megacolon (Clic here for more details about this article) |
6/16. multiple endocrine neoplasia type II B with symptoms suggesting Hirschsprung's disease: a case report.A 3-year-old child was referred with a tentative diagnosis of Hirschsprung's disease because of life-long constipation and "megacolon" demonstrated radiographically. Our rectal biopsy revealed hyperganglionosis suggestive of multiple endocrine neoplasia (men) type II B. This, in addition to an elevated serum calcitonin level, prompted surgical removal of her thyroid, which appeared grossly normal but on sectioning, contained a medullary carcinoma in each lobe. She remains disease-free 5 years later. Gastrointestinal symptoms are a significant component of the men type II B syndrome, and often antedate the full phenotypic expression of the syndrome and the development of potentially lethal endocrine neoplasms. On the basis of this experience, it is recommended that men II B be included in the differential diagnosis of chronic constipation.- - - - - - - - - - ranking = 0.16666666666667keywords = megacolon (Clic here for more details about this article) |
7/16. urinary retention due to idiopathic megacolon.A 58-year-old man with neurogenic bladder dysfunction was hospitalized with chief complaints of urinary retention and abdominal distention. He had been treated for neurogenic bladder due to cerebral infarction for 3 years. The pelvic CT scan and excretory urogram revealed an obstruction of the neck of the bladder due to an abundant stool, which was found to have resulted from adult idiopathic megacolon. A permanent colostomy with sigmoid resection was established. The postoperative urodynamic examination demonstrated improvement of micturition.- - - - - - - - - - ranking = 0.83333333333333keywords = megacolon (Clic here for more details about this article) |
8/16. Can idiopathic megacolon cause functional motor abnormalities in the upper gastrointestinal tract?Upper gastrointestinal symptoms are often found in patients with chronic constipation. We report a case of a child with severe chronic constipation due to idiopathic megacolon with megarectum, in which small-bowel motor abnormalities, demonstrated before treatment, were corrected by therapy. Possible pathophysiological mechanisms are discussed.- - - - - - - - - - ranking = 0.83333333333333keywords = megacolon (Clic here for more details about this article) |
9/16. rectal prolapse in scleroderma: case report and review of the colonic complications of scleroderma.Scleroderma of the colon is commonly associated with constipation, as was the case in a 70-year-old woman with rectal prolapse described by the authors. The chronic constipation in this patient may have been the cause of her rectal prolapse, but the onset of the prolapse and scleroderma at about the same time suggest that the scleroderma may have been a causative factor. A Ripstein repair of the prolapse was carried out. The authors discuss some of the complications of colonic scleroderma, which include megacolon, transverse and sigmoid colonic volvulus, telangiectasia, stenosis and diverticula and stercoral ulceration.- - - - - - - - - - ranking = 0.16666666666667keywords = megacolon (Clic here for more details about this article) |
10/16. multiple endocrine neoplasia (men) syndrome type IIB: gastrointestinal manifestations.multiple endocrine neoplasia syndrome IIB is an inherited autosomal dominant disorder with variable penetrance. Multiple organ systems are involved with a characteristic triad of medullary thyroid carcinoma, pheochromocytoma, and alimentary tract ganglioneuromas. Most patients have characteristic facies with patulous lips and thickened tarsal plates of the eyelids. The entire gastrointestinal tract can be involved from tongue to anus. tongue nodules are common. Altered intestinal motility, dilation, diverticula, and mucosal abnormality may be seen radiographically. Gastrointestinal symptoms are common, may be the presenting manifestation of the syndrome early in life, and allow the radiologist to suggest the proper diagnosis. Five patients are described. All had megacolon.- - - - - - - - - - ranking = 0.16666666666667keywords = megacolon (Clic here for more details about this article) |
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