1/53. corynebacterium pseudodiphtheriticum pneumonia in an immunocompetent patient.corynebacterium pseudodiphtheriticum is a coryneform and diphtheromorphic bacteria rarely found as a cause of pneumonia in immunocompetent hosts. A case of an immunocompetent patient with C. pseudodiphtheriticum pneumonia is presented. This infection responded well to initial empirical treatment with cefotaxime. Very few cases of pneumonia associated with C. pseudodiphtheriticum have been described in the medical literature, this organism mainly being found in immunocompromised hosts. We report a case of pneumonia in an immunocompetent patient in which C. pseudodiphtheriticum was the only micro-organism isolated.- - - - - - - - - - ranking = 1keywords = coryneform (Clic here for more details about this article) |
2/53. Isolation and characterization of a black-pigmented corynebacterium sp. from a woman with spontaneous abortion.An unusual black-pigmented coryneform bacterium was isolated from the urogenital tract of a woman who experienced a spontaneous abortion during month 6 of pregnancy. Biochemical and chemotaxonomic analyses demonstrated that the unknown bacterium belonged to the genus corynebacterium. Phylogenetic analysis based on 16S rRNA sequences (GenBank accession no. AF220220) revealed that the organism was a member of a distinct subline which includes uncultured corynebacterium MTcory 1P (GenBank accession no. AF115934), derived from prostatic fluid, and corynebacterium CDC B8037 (GenBank accession no. AF033314), an uncharacterized black-pigmented coryneform bacterium. On the basis of chemotaxonomic and phylogenetic evidence, this organism probably represents a new species and is most closely related to the uncharacterized Centers for disease Control and Prevention group 4 coryneforms. Our strain is designated CN-1 (ATCC 700975).- - - - - - - - - - ranking = 3.0000141309154keywords = coryneform, group (Clic here for more details about this article) |
3/53. Infection of the skin caused by corynebacterium ulcerans and mimicking classical cutaneous diphtheria.Extrapharyngeal infections caused by corynebacterium ulcerans have rarely been reported previously, and diphtheria toxin production has usually not been addressed. This case demonstrates that strains of C. ulcerans that produce diphtheria toxin can cause infections of the skin that completely mimic typical cutaneous diphtheria, thereby potentially providing a source of bacteria capable of causing life-threatening diseases in the patient's environment. Therefore, it is recommended to screen wound swabs for coryneform bacteria, identify all isolates, carefully assess possible toxin production, and send questionable strains to a specialist or a reference laboratory.- - - - - - - - - - ranking = 1keywords = coryneform (Clic here for more details about this article) |
4/53. mortality from grossly encrusted bilateral pyelitis, ureteritis, and cystitis by corynebacterium group D2.This is the first report of death due to gross encrustations of the entire upper urinary tract and bladder by corynebacterium group D2 in a man with no history of renal transplantation or prolonged catheterizations. This case demonstrates that debilitated patients with a prior endoscopic procedure are at risk for this disease process. Prolonged treatment with appropriate antibiotics, acidification of the urine, and removal of crusts is essential for proper management.- - - - - - - - - - ranking = 7.0654576801383E-5keywords = group (Clic here for more details about this article) |
5/53. Multidrug-resistant corynebacterium striatum pneumonia in a heart transplant recipient.corynebacterium striatum is a rare, but likely underreported, cause of serious infections in immunocompromised hosts and generally is susceptible to multiple classes of antimicrobial agents. Here we report the first case of C. striatum infection in a solid organ transplant recipient. Three years after heart transplantation, a 58-year-old man developed bilateral pneumonia and pulmonary embolism. He did not improve with levofloxacin, piperacillin/tazobactam, and heparin treatment. A homogeneous population of abundant gram-positive rods was repeatedly demonstrated in sputum and bronchoalveolar lavage fluid, and C. striatum was grown in pure culture. The isolate was unusual for its multidrug-resistant (MDR) antimicrobial susceptibility pattern. The pneumonia resolved with 4 weeks of vancomycin therapy, in combination with rifampin given only during the first 2 weeks of treatment. The isolation of coryneforms ("diphtheroids") is often attributed to contamination. Their abundant presence on direct examination of specimens and/or their growth in pure culture suggest a pathogenic role, however, and indicate the need for accurate microbiological identification, particularly in immunocompromised hosts who have been hospitalized and previously treated with antibiotics. Combination therapy that includes vancomycin may be the most prudent treatment for MDR C. striatum infections.- - - - - - - - - - ranking = 1keywords = coryneform (Clic here for more details about this article) |
6/53. teicoplanin treatment of alkaline encrusted cystitis due to corynebacterium group D2.Alkaline-encrusted cystitis (AEC) is a chronic inflammation of the bladder related to the gram-positive bacillus corynebacterium Group D2. This germ is often resistant to many antibiotics and is particularly difficult to eradicate in the particular setting of AEC. The authors report two observations of AEC treated with the glycopeptid antibiotic teicoplanin, which led to permanent cure of AEC.- - - - - - - - - - ranking = 5.6523661441106E-5keywords = group (Clic here for more details about this article) |
7/53. A case of urinary tract infection caused by corynebacterium urealyticum and coryneform group F1.A case of urinary tract infection (UTI) caused by a fastidious, urea-splitting, antibiotic-sensitive coryneform, identified as CDC group F1, is described. The patient suffered from encrusted cystitis and had had previous and persistent UTIs caused by corynebacterium urealyticum (formerly CDC group D2). Bacteriological cure was achieved after one month of treatment with amoxicillin plus acetohydroxamic acid.- - - - - - - - - - ranking = 10.862917915779keywords = coryneform group, coryneform, group (Clic here for more details about this article) |
8/53. Three cases of opportunistic infection caused by propionic acid producing corynebacterium minutissimum.Propionic acid producing strains of corynebacterium minutissimum were isolated from three patients with opportunistic infections. One neutropenic patient was undergoing chemotherapy for prolymphocytic leukemia; the other two patients were undergoing hemodialysis and peritoneal dialysis respectively. An unusual feature of these three strains was their resistance to several antibiotics, which is seldom seen in diphtheroids other than corynebacterium jeikeium and CDC group D2.- - - - - - - - - - ranking = 1.4130915360277E-5keywords = group (Clic here for more details about this article) |
9/53. Antimicrobial susceptibilities of a corynebacterium CDC group I1 strain isolated from a patient with endocarditis.We encountered a case of native valve endocarditis due to corynebacterium CDC group I1 which was successfully controlled with antimicrobial agents alone. This organism and three other isolates of this group were susceptible to penicillin, vancomycin, and gentamicin. The combination of penicillin with subinhibitory concentrations of gentamicin resulted in a 1,000-fold decrease in CFU per milliliter at 24 h compared with penicillin alone. Augmentation of killing was noted also with vancomycin plus gentamicin but to a degree that did not meet strict criteria for bactericidal synergism.- - - - - - - - - - ranking = 8.478549216166E-5keywords = group (Clic here for more details about this article) |
10/53. Fatal pneumonia caused by corynebacterium group JK after treatment of staphylococcus aureus pneumonia.A 76-year-old man who was admitted to the hospital because of chronic renal insufficiency and chronic hepatitis died of corynebacterium group JK pneumonia, after showing a slight improvement by treatment of staphylococcus aureus with sulbactam/cefoperazone and minocycline. Transtracheal aspiration (TTA) just before his death revealed numerous gram-positive bacilli phagocytized by many neutrophils and more than 10(8) colony forming units (CFU)/ml of corynebacterium group JK. A drug susceptibility test showed corynebacterium group JK was resistant to many antibiotics, with the exception of vancomycin and amikacin.- - - - - - - - - - ranking = 9.8916407521936E-5keywords = group (Clic here for more details about this article) |
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