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1/40. corynebacterium jeikeium native valve endocarditis following femoral access for coronary angiography.

    We present a unique case of rapidly fatal native aortic-valve endocarditis due to corynebacterium jeikeium, with inoculation as a complication of repeated femoral vascular access for coronary angiography.
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ranking = 1
keywords = endocarditis
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2/40. Nosocomial endocarditis caused by corynebacterium amycolatum and other nondiphtheriae corynebacteria.

    The nondiphtheriae corynebacteria are uncommon but increasingly recognized as agents of endocarditis in patients with underlying structural heart disease or prosthetic-valves. We describe three cases of nosocomial endocarditis caused by nondiphtheriae corynebacteria, including the first reported case of corynebacterium amycolatum, endocarditis. These all occurred in association with indwelling intravascular devices.
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ranking = 1.4
keywords = endocarditis
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3/40. A case of prosthetic valve endocarditis caused by corynebacterium hofmanni and candida albicans.

    The case is described of a 49-year-old woman who developed endocarditis in relation to the prosthetic valve two months after insertion of a Starr-Edwards mitral valve prosthesis. Initially corynebacterium hofmanni was isolated from blood culture. Later, while the patient was receiving antibacterial chemotherapy, candida albicans was also isolated and she was treated with 5-fluorocytosine. A cure was effected without the need for further valve replacement.
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ranking = 1
keywords = endocarditis
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4/40. corynebacterium striatum first reported case of prosthetic valve endocarditis.

    We describe the case of a prosthetic valve endocarditis in a 72-year-old woman. corynebacterium striatum was isolated in the blood samples. This organism has been described in a few cases of native valve endocarditis, but this is the first case reported of prosthetic valve endocarditis.
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ranking = 1.4
keywords = endocarditis
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5/40. An unusual case of infective endocarditis.

    A rare case of corynebacterium striatum endocarditis on a bioprosthetic aortic valve replacement, treated medically, is reported. The presentation was subacute, and initially endocarditis screening was negative. Because of the failure of symptoms to settle further screening was performed which confirmed the organism in several sets of blood cultures. This emphasises the importance of persistent screening for endocarditis if the history raises any suspicion of this potentially serious infection, especially in the presence of prosthetic valves.
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ranking = 1.4
keywords = endocarditis
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6/40. Native valve endocarditis with aorta-to-left atrial fistula due to corynebacterium amycolatum.

    Infective endocarditis remains a pathology with a high rate of complications and mortality. One of the most dramatic complications is abscess formation. A rare evolution of abscess formation is the development of fistula. We describe an 88-year-old woman with an aortic root abscess and aorta-to-left atrial fistula. To our knowledge this has only been described with streptococcus species as causative micro-organism. In this case the abscess was caused by corynebacterium amycolatum, which is an infrequently found micro-organism.
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ranking = 1
keywords = endocarditis
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7/40. Infectious endocarditis due to corynebacterium xerosis.

    corynebacterium xerosis is a rare cause of endocarditis, mainly affecting immunocompromised patients and those with predisposing cardiovascular lesions. While often considered a blood culture contaminant, serious infections by this organism have been reported. C. xerosis endocarditis is associated with poor outcomes that could be potentially improved by early recognition and treatment.
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ranking = 1.2
keywords = endocarditis
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8/40. Pseudoaneurysm from the mitral-aortic intervalvular fibrosa following endocarditis.

    A rare case of a pseudoaneurysm from the mitral-aortic intervalvular fibrosa following bacterial endocarditis in a 17-year-old male is presented. Destructive infection secondarily involved the mitral-aortic intervalvular fibrosa. Perforation of this portion resulted in the formation of the pseudoaneurysm situated at the base of the left ventricle between the aorta and the left atrium. With echocardiography, computed topography, angiography, and magnetic resonance imaging (MRI), a pseudoaneurysm was diagnosed. MRI especially revealed detailed information and the extension of pseudoaneurysm. Our patient underwent resection of the pseudoaneurysm, reconstruction of left ventricular outflow with glutaraldehyde-preserved bovine pericardium, and replacement of the aortic valve. His postoperative course was uneventful. No recurrence of endocarditis was detected in the following year.
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ranking = 1.2
keywords = endocarditis
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9/40. Antimicrobial susceptibilities of a corynebacterium CDC group I1 strain isolated from a patient with endocarditis.

    We encountered a case of native valve endocarditis due to corynebacterium CDC group I1 which was successfully controlled with antimicrobial agents alone. This organism and three other isolates of this group were susceptible to penicillin, vancomycin, and gentamicin. The combination of penicillin with subinhibitory concentrations of gentamicin resulted in a 1,000-fold decrease in CFU per milliliter at 24 h compared with penicillin alone. Augmentation of killing was noted also with vancomycin plus gentamicin but to a degree that did not meet strict criteria for bactericidal synergism.
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ranking = 1
keywords = endocarditis
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10/40. Successful treatment of corynebacterium striatum endocarditis with daptomycin plus rifampin.

    OBJECTIVE: To report a case of corynebacterium striatum endocarditis that was treated successfully with daptomycin plus rifampin following an unsuccessful attempt at vancomycin desensitization and failure of linezolid therapy. CASE SUMMARY: A 46-year-old woman with hemodialysis-dependent chronic renal failure was admitted for a graft-related infection. She presented with C. striatum endocarditis that was treated with daptomycin plus rifampin due to a history of allergies to vancomycin and beta-lactam antibiotics and failure of linezolid therapy. The patient received daptomycin and rifampin for a total of 6 weeks. Three months after completion of treatment, no recurrence of endocarditis was evident. DISCUSSION: daptomycin is a lipopeptide antibiotic, with rapid bactericidal activity. It has demonstrated efficacy in animal models of staphylococcal, streptococcal, and enterococcal endocarditis. case reports of its activity in methicillin-resistant staphylococcus aureus endocarditis have also been documented. CONCLUSIONS: daptomycin, which has shown in vitro activity against C. striatum, may be a viable treatment option for patients with C. striatum endocarditis who are either allergic or refractory to traditional antibiotics.
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ranking = 2
keywords = endocarditis
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