1/37. corynebacterium pseudodiphtheriticum: an easily missed respiratory pathogen in hiv-infected patients.Despite being a well-known respiratory pathogen for immunocompromised patients, corynebacterium pseudodiphtheriticum has uncommonly been reported to occur in persons with infection attributable to hiv virus. We report three cases of respiratory tract infection attributable to C. pseudodiphtheriticum in hiv-infected patients and review the four previous cases from the medical literature. All of them were male with a median cd4 lymphocyte count of 110 cells/mm3 (range, 18-198/mm3); five of the seven cases occurred in persons for whom AIDS was diagnosed previously. The onset of symptomatology was usually acute and the most common radiographic appearance was alveolar infiltrate (six patients) with cavitation (two patients) and pleural effusion (two patients). In five of the seven cases, C. pseudodiphtheriticum was isolated from bronchoscopic samples and in the remaining two cases was recovered from lung biopsy (one patient) and sputum (one patient). In the three patients reported herein and in one previous case from the medical literature, quantitative culturing of bronchoscopic samples obtained through either bronchoalveolar lavage or protected brush catheter procedures yielded more than 10(3) CFU/mL. All the strains tested were susceptible to penicillin and vancomycin. Resistance to macrolides was common. Recovery was observed in six of the seven patients. C. pseudodiphtheriticum should be regarded as a potential respiratory pathogen in hiv-infected patients. This infection presents late in the course of hiv disease and it seems to respond well to appropriate antibiotic treatment in most of the cases. This easily overlooked pathogen should be added to the list of organisms implicated in respiratory tract infections in this population.- - - - - - - - - - ranking = 1keywords = respiratory tract infection, tract infection, respiratory tract, tract (Clic here for more details about this article) |
2/37. Isolation and characterization of a black-pigmented corynebacterium sp. from a woman with spontaneous abortion.An unusual black-pigmented coryneform bacterium was isolated from the urogenital tract of a woman who experienced a spontaneous abortion during month 6 of pregnancy. Biochemical and chemotaxonomic analyses demonstrated that the unknown bacterium belonged to the genus corynebacterium. Phylogenetic analysis based on 16S rRNA sequences (GenBank accession no. AF220220) revealed that the organism was a member of a distinct subline which includes uncultured corynebacterium MTcory 1P (GenBank accession no. AF115934), derived from prostatic fluid, and corynebacterium CDC B8037 (GenBank accession no. AF033314), an uncharacterized black-pigmented coryneform bacterium. On the basis of chemotaxonomic and phylogenetic evidence, this organism probably represents a new species and is most closely related to the uncharacterized Centers for disease Control and Prevention group 4 coryneforms. Our strain is designated CN-1 (ATCC 700975).- - - - - - - - - - ranking = 0.00069072146452887keywords = tract (Clic here for more details about this article) |
3/37. corynebacterium macginleyi isolated from urine in a patient with a permanent bladder catheter.An 82-y-old male patient with a neurogenic bladder and vesical stones presented with a urinary tract infection caused by corynebacterium macginleyi. This is the first case of isolation of C. macginleyi from a non-conjunctival specimen. The patient recovered fully with antimicrobial treatment.- - - - - - - - - - ranking = 0.078371982674568keywords = tract infection, tract (Clic here for more details about this article) |
4/37. mortality from grossly encrusted bilateral pyelitis, ureteritis, and cystitis by corynebacterium group D2.This is the first report of death due to gross encrustations of the entire upper urinary tract and bladder by corynebacterium group D2 in a man with no history of renal transplantation or prolonged catheterizations. This case demonstrates that debilitated patients with a prior endoscopic procedure are at risk for this disease process. Prolonged treatment with appropriate antibiotics, acidification of the urine, and removal of crusts is essential for proper management.- - - - - - - - - - ranking = 0.00069738704616355keywords = tract, upper (Clic here for more details about this article) |
5/37. Fatal septic shock caused by corynebacterium D2.BACKGROUND: Septic shock remains one of the leading causes of mortality in critically ill patients. Optimal management depends on prompt diagnosis with identification of the causative organisms to allow appropriate antibiotic therapy. PATIENT: We report the first case of septic shock caused by corynebacterium D2, a micro-organism that can cause encrusted cystitis and pyelitis of transplanted kidneys or, more rarely, native kidneys. diagnosis rests on identification of risk factors, positive urine cultures, and computed tomography results. Despite optimal treatment our patient died with persistent encrusted pyelitis. CONCLUSIONS: corynebacterium D2 is known to cause chronic inflammation of the bladder and proximal urinary tract but can also cause severe septic shock in immunocompetent patients.- - - - - - - - - - ranking = 0.00069072146452887keywords = tract (Clic here for more details about this article) |
6/37. Is a black-pigmented corynebacterium species an opportunistic pathogen during pregnancy? literature review and report of 3 new cases.Isolation of black-pigmented corynebacterium species from human clinical samples has been reported, although rarely. review of the medical literature revealed 3 reports of culture isolation of these unusual bacteria. All were recovered from the female genital tract, and 1 case was associated with spontaneous abortion. Genetic characterization of these isolates indicates that they are similar and probably represent a novel pathogen in the genus corynebacterium. We report 3 additional bacterial isolates sharing similar phenotypic and/or genotypic characteristics that were recovered from the genital tract of women who had complications of pregnancy. Similarities in these cases suggest that this newly recognized corynebacterium species might be an opportunistic pathogen in pregnancy.- - - - - - - - - - ranking = 0.0013814429290577keywords = tract (Clic here for more details about this article) |
7/37. A case of urinary tract infection caused by corynebacterium urealyticum and coryneform group F1.A case of urinary tract infection (UTI) caused by a fastidious, urea-splitting, antibiotic-sensitive coryneform, identified as CDC group F1, is described. The patient suffered from encrusted cystitis and had had previous and persistent UTIs caused by corynebacterium urealyticum (formerly CDC group D2). Bacteriological cure was achieved after one month of treatment with amoxicillin plus acetohydroxamic acid.- - - - - - - - - - ranking = 0.39185991337284keywords = tract infection, tract (Clic here for more details about this article) |
8/37. hyperammonemia with complex urinary tract anomaly: a case report.hyperammonemia has been reported rarely in the pediatric age group in systemically ill patients. All cases resulted from infections with urea splitting organisms, which are more common among patients who have undergone surgical procedures on the urinary tract. The authors report for the first time in the pediatric literature, one patient who presented with hyperammonemic encephalopathy that resulted from urinary tract infection with staphylococcus epidermidis and corynebacterium sp.- - - - - - - - - - ranking = 0.081825589997213keywords = tract infection, tract (Clic here for more details about this article) |
9/37. Late-onset corynebacterium endophthalmitis following laser posterior capsulotomy.Four months following uncomplicated cataract extraction, a patient underwent Nd:YAG laser posterior capsulotomy. Three days later, she presented with pain, hand motions vision, and severe anterior uveitis and vitritis. A coincident retinal detachment led to a delay in diagnosing the etiology of this intraocular inflammation. After recurrent episodes of inflammation that were initially responsive to corticosteroids, the patient underwent a vitrectomy, lens explantation, capsulectomy, and intravitreal antibiotic injections, which resulted in complete resolution of the intraocular inflammation with a best-corrected visual acuity of 20/60. corynebacterium species was ultimately cultured from the capsular tissue. The release of sequestered bacterial organisms must be considered in the differential diagnosis of persistent or unusually intense inflammation following laser posterior capsulotomy.- - - - - - - - - - ranking = 0.00069072146452887keywords = tract (Clic here for more details about this article) |
10/37. Postoperative corynebacterium macginleyi endophthalmitis.A 72-year-old man with chronic endophthalmitis who received steroid treatment for 3 months came to our center. Sterile endophthalmitis after cataract extraction had been diagnosed. Aqueous samples including smears, classic cultures, and polymerase chain reaction were taken for microbiological study. Amplified dna was sequenced to identify the pathogen. polymerase chain reaction amplification was positive for bacteria. sequence analysis showed corynebacterium macginleyi as the causal agent in 48 hours. The culture and smear stains from the ocular samples were negative. The patient was successfully treated with vancomycin. polymerase chain reaction and subsequent dna-typing were useful in detecting the microorganisms that caused the chronic endophthalmitis.- - - - - - - - - - ranking = 0.00069072146452887keywords = tract (Clic here for more details about this article) |
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