Cases reported "Cross Infection"

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1/34. Fatal serratia marcescens meningitis and myocarditis in a patient with an indwelling urinary catheter.

    serratia marcescens is commonly isolated from the urine of patients with an indwelling urinary catheter and in the absence of symptoms is often regarded as a contaminant. A case of fatal serratia marcescens septicaemia with meningitis, brain abscesses, and myocarditis discovered at necropsy is described. The patient was an 83 year old man with an indwelling urinary catheter who suffered from several chronic medical conditions and from whose urine serratia marcescens was isolated at the time of catheterisation. serratia marcescens can be a virulent pathogen in particular groups of patients and when assessing its significance in catheter urine specimens, consideration should be given to recognised risk factors such as old age, previous antibiotic treatment, and underlying chronic or debilitating disease, even in the absence of clinical symptoms.
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keywords = abscess
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2/34. Nosocomial pneumonia likely caused by stenotrophomonas maltophilia in two patients with polymyositis.

    We report two cases of polymyositis (PM) complicated with nosocomial pneumonia probably caused by stenotrophomonas maltophilia, which was resistant to multiple antimicrobials. In the first case, the chest CT findings and high serum endotoxin level as well as sputum culture results were helpful for the proper diagnosis and the therapy was successful. However the second patient died of a lung abscess in spite of the intensive antibiotic therapy. When PM patients develop pneumonia unresponsive to various antibiotics, a multi-drug-resistant bacteria such as stenotrophomonas maltophilia should be considered as the pathogen.
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keywords = abscess
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3/34. enterobacter sakazakii infections among neonates, infants, children, and adults. case reports and a review of the literature.

    enterobacter sakazakii can cause serious infections especially among the very young and the elderly. It continues to be more common among neonates and infants than adults. Its tropism for the central nervous system in neonates and infants remains a mystery. Among neonates and infants, E. sakazakii has a propensity to cause meningitis resulting in ventriculitis, brain abscess or cyst formation, and development of hydrocephalus requiring ventricular-peritoneal shunt. Computed tomography of the head is therefore useful in following patients with E. sakazakii meningitis. mortality and morbidity of E. sakazakii meningitis is high, and virtually all patients recovering from the central nervous system infection suffered mental and physical developmental delays. The case-fatality rate decreased among patients with meningitis treated with the third-generation cephalosporins. Most adults with E. sakazakii infection had serious underlying diseases and 50% of the adults with the infection had malignancies. However there has never been a known case of meningitis. Increasing antibiotic resistance among enterobacter species should lead one to consider using the carbapenems or the newer cephalosporins in combination with a second agent such as an aminoglycoside. Limited data suggest that trimethoprim-sulfamethoxazole may be a useful agent in the treatment of infections caused by the enterobacter species, especially in view of the production of extended-spectrum beta-lactamases capable of inactivating the cephalosporins and extended-spectrum penicillin.
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keywords = abscess
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4/34. Unusual nosocomial transmission of mycobacterium tuberculosis.

    This case report describes how a late diagnosis of a tuberculous abscess combined with daily irrigation of the wound without barrier precautions led to nosocomial transmission of mycobacterium tuberculosis. Among 372 hospital contacts, 16 had a tuberculin skin test conversion and two developed active pulmonary tuberculosis with the same strain as that isolated from the index patient's abscess. When a culture from an abscess remains negative, mycobacterium tuberculosis infection should be considered. Furthermore, wound irrigation should be done with proper barrier precautions because infectious aerosols can be created during the irrigation process.
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ranking = 3
keywords = abscess
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5/34. serratia marcescens in the neonatal intensive care unit: re-emphasis of the potentially devastating sequelae.

    BACKGROUND: It is known that infections with serratia marcescens can take a progressive course in preterm infants and that meningoencephalitis with this pathogen exhibits an extremely bad neurologic prognosis. methods AND RESULTS: We report on five cases of septicemia with serratia marcescens in preterm infants during a nosocomial outbreak. Three patients developed meningoencephalitis with brain abscesses. Mild clinical and laboratory findings of infection contrasted with destructive findings on MRI scan. All five patients survived, those with isolated bacteremia without neurologic sequelae. CONCLUSION: When serratia marcescens is isolated from any source in a neonatal intensive care unit, preventive measures including strict hygiene and cohorting of infants must be implemented immediately since this pathogen seems to exhibit specific affinity for the central nervous system and serratia marcescens meningoencephalitis takes a progressive and destructive course despite antibiotic therapy.
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keywords = abscess
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6/34. Fatal lung abscess due to lactobacillus casei ss rhamnosus.

    A fatal case of community acquired pneumonia due to lactobacillus casei ss rhamnosus is reported. Clinicians should be aware of this type of pneumonia.
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ranking = 4
keywords = abscess
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7/34. Neonatal salmonella panama infection with meningitis.

    Three full-term neonates contracted a hospital infection with salmonella panama derived from the mother of one. Two had bacteraemia and meningitis; one developed a brain abscess and the other recurrent meningitis at two months. The third neonate had gastroenteritis only. Six months later they had developed normally and two were still excreting salmonellae in the stools.
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ranking = 1
keywords = abscess
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8/34. Brain abscesses after serratia marcescens infection on a neonatal intensive care unit: differences on serial imaging.

    Serratia are known to be a possible cause of severe cerebral infections in neonates. We describe imaging of three premature infants infected with serratia marcescens. Born in the 31( st), 25( th) and 28( th) weeks of gestation, they presented with signs of septicaemia on postnatal days 9, 24 and 32. Initial sonography showed cysts in the first child, two areas with anechoic centre and echogenic rim in the second, and several echogenic areas in the third. Lesions were seen on CT, of low density in two cases and minimally increased density in the third. MRI in the first patient showed cysts with incomplete contrast enhancement of the lesions, while patient 2 showed five ring-enhancing fluid-containing lesions with thick walls. In the third patient two abscesses with contrast enhancement and several high-signal spots were seen. We discuss the pathophysiology of the lesions and the impact of the various imaging methods.
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ranking = 5
keywords = abscess
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9/34. central nervous system infections due to abiotrophia and Granulicatella species: an emerging challenge?

    Although abiotrophia and Granulicatella species, previously referred to as nutritionally variant streptococci, were initially identified over 40 years ago, isolation of these pathogens from the central nervous system (CNS) was first noted only recently. Recognition of CNS involvement with these organisms is of great concern given the association of abiotrophia/Granulicatella infections with increased morbidity and mortality as well as greater bacteriologic failure and relapse rates. We describe A. defectiva and G. adiacens CNS infections in two patients and review the existing literature of CNS involvement with these bacteria. The clinical presentation and initial cerebrospinal fluid analysis has varied substantially across reported patients. While most infections have been characterized primarily by a localized infection (e.g., abscess), evidence of meningitis has usually also been present. Furthermore, nearly all cases have followed neurosurgical procedures suggesting possible introduction of the organism into the CNS at the time of surgery. Given the significant negative clinical impact of abiotrophia/Granulicatella infections, elucidation of the emerging epidemiology of CNS infections with these bacteria is warranted.
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ranking = 1
keywords = abscess
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10/34. acinetobacter skin abscess in a neonate.

    Although acinetobacter is usually a species of low virulence, it is becoming increasingly more important as a cause of hospital outbreaks, particularly on intensive care units. Antibiotic resistance can develop rapidly. This organism has not been reported to cause skin abscesses previously. We describe a case of a neonate who developed an acinetobacter abscess on our neonatal intensive care unit.
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ranking = 6
keywords = abscess
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