1/4. Cold agglutinin disease--the importance of cutaneous signs.We present the case of a woman where the diagnosis of cold agglutinin disease could be made after we had noticed slight cutaneous manifestations during a routine examination. Leading symptoms were livedo reticularis of the thighs and a history of acrocyanosis and Raynaud's phenomenon upon cold exposure. The current knowledge about the etiology, clinical presentation and treatment of the disease is briefly discussed.- - - - - - - - - - ranking = 1keywords = livedo reticularis, reticularis, livedo (Clic here for more details about this article) |
2/4. Blue digit syndrome: treatment with percutaneous transluminal angioplasty.Ten patients with classical blue digit syndrome were treated with percutaneous transluminal angioplasty (PTA). None experienced embolization. Nine were clinically improved; in eight, microembolization did not recur during follow-up of 7-86 months (mean, 28 months). Three clinical and three angiographic features were common to these eight patients: (a) few clinical episodes of microembolization; (b) no episodes of macroembolization; (c) no livedo reticularis in the affected extremity, and no symptoms of systemic cholesterol embolization; (d) focal, high-grade (greater than 90%) stenoses that were hemodynamically significant; (e) no diffuse atheromas in the aorta; (f) patent tibial runoff arteries. Affected patients with these clinical and angiographic characteristics make up a subgroup, previously unrecognized, to the authors' knowledge, in whom PTA followed by antiplatelet therapy should be the initial treatment of choice. The blue digit syndrome in these patients was probably due to microemboli composed of fibrinoplatelet aggregates rather than cholesterol debris.- - - - - - - - - - ranking = 1keywords = livedo reticularis, reticularis, livedo (Clic here for more details about this article) |
3/4. livedo reticularis and purpura: presenting features in fulminant pneumococcal septicemia in an asplenic patient.We report a case of pneumococcal septicemia in an asplenic, otherwise healthy, 31-year-old patient. He presented with a viral prodrome and skin findings of purpura and livedo reticularis. blood cultures identified streptococcus pneumoniae. Rapid initiation of appropriate therapy resulted in resolution of the infection and clearing of all skin signs.- - - - - - - - - - ranking = 1.8332933877504keywords = livedo reticularis, reticularis, livedo (Clic here for more details about this article) |
4/4. livedo reticularis associated with hereditary protein c deficiency and recurrent thromboembolism.We report the occurrence of livedo reticularis in a patient with symptomatic hereditary type 1 protein c deficiency. antithrombin iii deficiency and the antiphospholipid syndrome may also be associated with livedo reticularis, and we suggest that a thrombophilia screen may be a useful investigation in a patient with otherwise unexplained livedo, particularly if there is a personal or family history of thromboembolism.- - - - - - - - - - ranking = 2.9014337883291keywords = livedo reticularis, reticularis, livedo (Clic here for more details about this article) |