1/20. Multiple nodular metastases in mesenteric panniculitis by uterine papillary serous adenocarcinoma (UPSC): CT appearance of a case.Intra-abdominal panniculitis is a thickening of the mesentery of the small/large intestine due to infiltration of lipid-laden macrophages associated with a variable amount of fibrosis. This condition is rarely associated with malignant neoplasms. We report the computed tomography (CT) findings of a patient treated for uterine papillary serous adenocarcinoma (UPSC). She had mesenteric panniculitis where metastatic tumor nodules implanted. This was the only intraperitoneal recurrence. To our knowledge, no such finding has been reported in the gynecologic and radiologic literature to date. On CT images, the differential diagnosis is with cystic dilatations of mesenteric lymph vessels.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
2/20. A lymph nodal capillary-cavernous hemangioma.A capillary-cavernous hemangioma in an obturator lymph node was found incidentally in a 64 year-old woman who had undergone unilateral salpingo-oophorectomy and lymphadenectomy for an ovarian neoplasm. Vascular tumors of lymph nodes are briefly reviewed including eight previously described nodal capillary-cavernous hemangiomas. The association with other splanchnic hemangiomas is pointed out and the likelihood that the lesion is a hamartoma rather than a true neoplasm is addressed. Despite its rarity, this entity needs to be recognized by lymphologists who image lymph nodes by lymphangiography as well as by lymph nodal pathologists.- - - - - - - - - - ranking = 2keywords = neoplasm (Clic here for more details about this article) |
3/20. Solid papillary-cystic tumor of the pancreas.BACKGROUND/AIMS: Clinical diagnosis and histopathological findings of a solid papillary-cystic tumor (SCT) of the pancreas may be unrecognized due to difficult differentiation between exocrine and endocrine pancreatic neoplasms, such as acinar cell carcinoma. Surgeons should be aware of this benign but rather uncommon lesion because complete excision is possible and successful. METHODOLOGY: The clinical course, surgical treatment and morphological findings of 3 patients with SCT are analyzed. The cases comprised 2 females and 1 male ranging in age from 49-72 years. The tumors were identified by histopathologic examination including immunostaining. RESULTS: The tumors, which were localized in the head, body and tail of the pancreas expressed a distinct immunostaining such as focal alpha1-antitrypsin in cases 1 and 2, and diffuse vimentin in all 3 cases. Keratin reactivity appeared positive in case 2 and 3, and neuroendocrine markers in case 2. The diversity of immunostaining emphasizes the tumor cell phenotype expressing epithelial, mesenchymal, and endocrine lines. After pancreatic resection 2 patients recovered successfully and 1 died. No lymph node or distal metastases were found at autopsy. CONCLUSIONS: Considering the favorable prognosis, the pancreatic SCT should be recognized by clinicians and pathologists, and surgically removed.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
4/20. Metastatic female adnexal tumor of probable Wolffian origin: a case report and review of the literature.female adnexal tumor of probable wolffian origin is a rare neoplasm that can present diagnostic difficulties. We report herein a case of a 60-year-old woman with female adnexal tumor of probable wolffian origin arising within the leaves of a broad ligament and, 5 years later, presenting with metastasis to the liver. The morphologic, immunohistochemical, ultrastructural, and dna ploidy findings of the original and metastatic tumor, differential diagnoses, and the results of the English-language literature review are presented.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
5/20. Primary papillary serous carcinoma of the peritoneum: CT-pathologic correlation.We present the CT findings of three cases of primary papillary serous carcinoma of the peritoneum. All patients presented with massive ascites. CT of the abdomen and pelvis showed omental caking in all patients. The parietal peritoneum of the pelvis showed diffuse enhancement with nodular thickening in all patients. No calcification was noted in the omental and parietal peritoneal masses, although psammoma bodies were present microscopically in one case. The ovaries were normal in size but showed a fine enhancing surface nodularity similar to the pelvic peritoneum. The CT findings of primary papillary serous carcinoma of the peritoneum are nonspecific, but this diagnosis should be considered when peritoneal carcinomatosis is seen on CT with normal-sized ovaries in the absence of other primary malignant neoplasms.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
6/20. Papillary serous carcinoma of the peritoneum: analysis of clonality of peritoneal tumors.Papillary serous carcinoma of the peritoneum (PSCP) is a primary neoplasm of peritoneal origin, and is histologically difficult to differentiate from papillary serous carcinoma of the ovary (PSCO). PSCP is frequently accompanied by many peritoneal tumors, and has been managed as a disseminated disease. In previous reports, however, the clonality of the tumors has not been fully discussed. Recently, the significant roles of the p53 and BRCA1 genes in PSCP have been reported. In this study, we investigated immunohistochemical staining for p53 proteins, and investigated p53 gene mutations, using dna sequencing analysis, to clarify the clonality of PSCP tumors. Immunohistochemically, all the tumor samples demonstrated nuclear overexpression of p53 proteins, and the dna sequencing analysis of the p53 gene showed diverse point mutations at codons 167 and 192 in two of four anatomically different tumors. In conclusion, the possibility of polyclonality of PSCP tumors is suggested.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
7/20. Oncocytic biliary cystadenocarcinoma is a form of intraductal oncocytic papillary neoplasm of the liver.Biliary cystadenocarcinoma with oncocytic differentiation was first reported in 1992. This is a report of a second case. The patient (a 71-year-old man) was admitted to our hospital complaining of abdominal fullness. Multicystic lesions were identified in the left hepatic lobe radiologically. The patient died of peritoneal dissemination of carcinoma 20 months later. At autopsy, the tumor of the left hepatic lobe was found to be composed of adjoining multiple cystic lesions and a solid lesion with infiltration of the hepatic hilus and peritoneal dissemination. Histologically, the multicystic lesions were covered by papillary neoplastic epithelial cells with an eosinophilic granular cytoplasm resembling that of oncocytes and a fine fibrovascular core. The cyst wall was fibrous, but there was no mesenchymal stroma. In the solid lesion and infiltrated areas, acidophilic and granular carcinoma cells formed small glandular or solid cord patterns with much mucin secretion (mucinous carcinoma). Immunohistochemically, carcinoma cells of both components were found to contain many mitochondria and showed the phenotypes of hepatocytes and cholangiocytes. Interestingly, the intrahepatic biliary tree also was invaded by carcinoma cells. This may be a case of intraductal oncocytic papillary neoplasm of the left hepatic lobe followed by secondary cystic dilatation of the affected bile duct.- - - - - - - - - - ranking = 5keywords = neoplasm (Clic here for more details about this article) |
8/20. Papillary serous carcinoma of peritoneum: case study and review of the literature on the differential diagnosis of malignant peritoneal tumors.The distinction between malignant mesothelioma and other malignant neoplasms diffusely involving the peritoneum is important for proper patient treatment. The extra-ovarian peritoneal serous papillary carcinoma is a rare, primary, multicentric peritoneal tumor that is morphologically identical to ovarian serous carcinoma of equivalent grade, but can spare or minimally involve the ovaries. We report such a tumor in a 65-year-old female who had abdominal swelling, ascites with positive cytology and a high grade of nuclear atypia in malignant cells as well as elevated serum CA125. Exploratory laparotomy findings of intrabdominal carcinomatosis were not accompanied by any evident primary site; so the diagnosis of a primary papillary serous neoplasia of the peritoneum was strongly considered. Since the amount of residual disease may be an important prognostic determining factor in primary papillary serous carcinoma of the peritoneum, the patient was debulked to no macroscopic disease and was then given platin-based chemotherapy. The tumor's differential diagnosis from malignant mesothelioma was based, apart from morphologic criteria, on the tumor's immunoreactivity to MOC-31, Ber-EP4 and TAG-72, as well as on the lack of immunostaining for keratin 5/6 and calretinin. Differential diagnosis from ovarian cancer was possible only after the pathological examination of the surgically resected ovaries; the tumor showed minimal superficial invasion of the ovarian cortex.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
9/20. Papillary cystadenocarcinoma arising from minor salivary glands in the anterior portion of the tongue: a case report.Papillary cystadenocarcinoma is a rare malignant neoplasm of the salivary gland. We report a case of papillary cystadenocarcinoma arising from the minor salivary gland in the anterior portion of the tongue of a 72-year-old male patient with a history of adenocarcinoma of the colon and prostate. Further, we discussed histopathological and clinical features of this lesion, and reviewed the literature.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
10/20. Multifocal papillary-cystic neoplasm of the pancreas.This case report describes the second known instance of a multifocal capillary pancreatic neoplasm. Both cases occurred in young African American females. A less-than-total pancreatectomy was performed to maintain endocrine function.- - - - - - - - - - ranking = 5keywords = neoplasm (Clic here for more details about this article) |
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