1/26. Testicular cysts: management and literature review.Simple testicular cysts are extremely rare; only 20 cases have been reported in the literature. Sites include the tunica albuginea, tunica vaginalis, and testicular epidermis. Conservative enucleation is an effective treatment for these lesions once ultrasound examination establishes that the mass is cystic. Such Enucleation salvages testicular tissue. In the cases discussed, two patients were initially evaluated for vague testicular discomfort and one patient for male infertility. All were subsequently found to have benign testicular cysts. All the cysts were excised, and all patients remain disease-free. Included is a case series report of simple testicular cysts and a review of the literature.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
2/26. "Pseudocyst of the auricle", othematoma and otoseroma: three faces of the same coin?Cystic swellings of the choncha of the ear without serious inflammation are routine findings for otolaryngologists. They are frequently diagnosed as othematoma or otoseroma and may be caused by traceable traumas or microtraumas. "Pseudocyst of the auricle" is defined as intracartilaginous cavity lacking epithelial lining. Thus, according to previous reports "pseudocysts" are supposed to occur due to chondromalacia within the cartilage. We recently observed four cases of "pseudocyst of the auricle" characterized by non-inflammatory, merely painless swellings on the anthelix part of the ears without history of any previous trauma. Incisional biopsies were taken from the dorsal side of the concha and freed 2 to 2.5 ml of viscous serous fluid. Histopathological examination of biopsy specimens showed regular epidermis overlying normal reticular dermis and perichondrium as well as regular cartilage in all patients. In the fourth patient the biopsy, additionally, revealed a tiny intracartilaginous cavity measuring 1 x 4 micrometers in diameter. Histopathologically "pseudocysts of the auricle" are reported to represent small intracartilaginous hollows lacking epithelial linings. Following previous descriptions they are located within the cartilage of the concha of the ear. Because of the small size of the intracartilaginous cavity they are unable to contain more than a few microliters of fluid. Therefore cystic swellings of the auricle containing comparatively large amounts of serous liquid must be located outside the cartilage. In this context the concept of "pseudocyst of the auricle" as reported, can only be seen as the third face of a coin that shows othematoma on the one and otoseroma on the other side.- - - - - - - - - - ranking = 2keywords = dermis (Clic here for more details about this article) |
3/26. Atrichia with papular lesions: electron microscopic observations of cystic lesions.Atrichia with papular lesions is a rare inherited skin disorder characterized by congenital atrichia with numerous papules. We describe a 27-year-old woman with atrichia, who had numerous papules on her scalp, nape, and axillae. Histologically, many keratinous cysts were seen in the middermis of a skin specimen from the nape. Electron microscopy showed that the developing keratinocytes in the walls of some cysts were rich in glycogen granules and had epidermoid keratinization with formation of keratohyaline granules and that laminated bodies were formed before keratinization. langerhans cells were often seen in the walls of the cysts. In addition, a broad glassy vitreous layer surrounded the cyst wall. From these findings, it was suggested that the cystic lesions might have originated from immature or incomplete hair follicles. In particular, the structure of the cyst wall corresponded well to infundibular and/or isthmal portions of the outer root sheath of the hair follicle.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
4/26. Membranous fat necrosis: a non-specific histological finding.Two patients presented with nodular lesions on their lower limbs. Histologically, the dermis, in one case, and the panniculus, in the other, displayed pseudocystic lesions delimited by a serpiginous membranous structure showing the staining characteristics of ceroid. One patient had sclerosing panniculitis while the other had a traumatic panniculitis.These cases illustrate that membranous fat necrosis is a non-specific histological finding and that multiple processes are involved in its etiopathogenesis.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
5/26. Cystic giant solitary trichoepithelioma.A case of a giant solitary trichoepithelioma is reported. The tumor was located on the thigh, extending from the deep dermis to the subcutaneous tissue with no epidermal contact, and showed a large central cystic cavity that measured 9 cm x 4 cm. We review the cases published under this and other names.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
6/26. Milium-like syringoma: a case study on histogenesis.BACKGROUND: Milium-like syringoma is a variant of syringoma first described in 1987. Only few cases have been reported in the literature. It may be misleading clinically, and its histogenesis has not been clarified. CASE REPORT: We present a case of periorbital milium-like syringoma, with studies on the histopathologic, histochemical, and immunohistochemical features. RESULTS: histology showed a large keratin-filled cyst in the upper portion of the lesion approximating the epidermis. Serial sections revealed that the cyst connected with the underlying syringomatous epithelial strands. Melanin was absent in the wall of the cyst, as demonstrated by Fontana-Masson stain. Cytokeratin 7 was expressed neither in the milia nor in the solid epithelial parts. carcinoembryonic antigen (CEA) reactivity was seen in the luminal cells of the keratinous cysts. However, in the largest keratin-filled cyst clinically suggesting a milium, only the lower half of the cyst was positive for CEA. These results proved that the milia were part of syringoma with eccrine duct differentiation. Fusion of the upper half of the largest cyst with the epidermis may explain the absence of CEA positivity in this part, analogous with eccrine duct milia. review of the literature indicated that this variant of syringoma occurs more often in Asians. CONCLUSION: We present evidence, and propose the histogenesis of milium-like syringoma, that it is a variant of syringoma with a prominent cystic component showing features of eccrine duct milia. Recognition of its nature is of therapeutic significance. Further studies are required to verify its clinical characteristics as compared with ordinary syringomas.- - - - - - - - - - ranking = 2keywords = dermis (Clic here for more details about this article) |
7/26. Onycholemmal carcinoma.We report on a slowly growing malignant tumor of the nail bed epithelium in a 69-year-old male. On light microscopic examination, the tumor was composed of: (1) some small cysts filled with eosinophilic, amorphous keratin and lined by an atypical squamous epithelium devoid of a granular layer and (2) solid nests and strands of atypical keratinocytes filling the dermis and penetrating the phalangeal bone. Because the nail bed epithelium is comparable to the outer root sheath, or trichilemma of the hair follicle, and since the reported tumor showed some analogies with trichilemmal carcinoma, we suggest that this entity be designated 'onycholemmal carcinoma'. disarticulation of the involved phalanx was performed and neither local recurrence nor distant metastasis was observed during 4 years of follow up.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
8/26. Folliculosebaceous cystic hamartoma with hair shaft fragments.We describe herein a 57-year-old Japanese male with a folliculosebaceous cystic hamartoma (FCH) presenting several hair shaft fragments in the cyst. Clinically, a skin-colored, dome-shaped, hard nodule, 5 x 4 mm in diameter was observed on the antitragus of his left ear. Histological examination revealed a large cystic structure surrounded by multiple mature sebaceous lobules and rudimentary hair follicules in the middle of the dermis. The cystic structure contained laminated orthokeratotic keratin and several hair shaft fragments. The fibrous stroma invaded the sebaceous lobules and obvious clefts were seen around the folliculosebaceous units located in the dermis. These features are characteristic histological findings of FCH. To our knowledge, this case is unusual with the presence of hair shaft fragments within the cystic structure. In addition, we discuss the histopathological findings of FCH and also review other cases of FCH in the literature.- - - - - - - - - - ranking = 2keywords = dermis (Clic here for more details about this article) |
9/26. Papillomavirus-infected keratinous cyst on the sole. A histologic, immunohistochemical, and electron microscopic study.A 17-year-old boy had a keratinous cyst on the sole. The keratinous cyst and its overlying epidermis had solitarily scattered keratinocytes, which contained a peculiar intracytoplasmic inclusion body above the lower spinous layer. immunohistochemistry and electron microscopy revealed that the nuclei of these cells had virions of papillomavirus. These virions appeared above the spinous layer. The inclusion bodies were highly eosinophilic masses in the viable layer, and slightly basophilic, fine granules in the cornified layer. Their number at any time was usually one. Their histologic and ultrastructural features and their N-(7-dimethylamino-4-methylcoumarinyl)-maleimide staining property were different from those of keratohyalin and from those of amyloid or hyaline body. Also the keratinous cyst was associated with colloid bodies, showing the lamellated figure in the subepithelial area.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
10/26. Hepatic cerebrospinal fluid pseudocyst: a case report and review of the literature.An abdominal pseudocyst is a rare, but important complication in patients with a ventriculo-peritoneal (VP) shunt insertion. Several predisposing factors for this complication have been suggested, including infection, obstruction or dislodgement, but the pathophysiology is still unknown. However, the abdominal inflammatory process is accepted widely as a hypothesis for the formation of an abdominal pseudocyst. In this study, we report the case of a 21-year-old male that presented with a high-grade fever, poor appetite, shortness of breath and unconsciousness 1 week after receiving a VP shunt insertion for obstructive hydrocephalus. ultrasonography and computed tomographic scans of the abdomen revealed a well-defined large hepatic cyst surrounding the peritoneal tube of the VP shunt. A hepatic cerebrospinal fluid (CSF) cyst was diagnosed and staphylococcus epidermis was cultured via CSF. After externalization of the VP shunt and adequate antibiotic treatment, the hepatic cyst was resolved. There was no recurrence observed in the regular follow up.- - - - - - - - - - ranking = 1keywords = dermis (Clic here for more details about this article) |
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