Cases reported "Dermatitis, Contact"

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1/46. Allergic contact dermatitis to a salicyclic acid plaster.

    We report two patients who developed allergic eczematous contact dermatitis to a salacid plaster used to treat plantar warts. Both patients were subsequently shown to be allergic to dehydroabietic acid, a resin contained in the plaster.
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2/46. Too hot to handle: an unusual exposure of HDI in specialty painters.

    BACKGROUND: Hexamethylene Diisocyanate (HDI) is a color stable aliphatic isocyanate that is used in specialty paints as a hardener. Due to the lower vapor pressure of its commercial biuret form, it is considered a relatively "safe" isocyanate from an exposure standpoint. This case series reports on an unusual toxic exposure to HDI. Between November 1993 and May 1994, seven specialty painters and one boiler maker who were working at three different power plants were examined at the Institute of Occupational and environmental health at west virginia University. At their respective work sites, HDI was applied to the hot surfaces of boilers that were not shut down, and allowed sufficient time to cool. Consequently, these workers were exposed to volatile HDI and its thermal decomposition products. methods: All of these workers underwent a complete physical examination, spirometry, and methacholine challenge testing. RESULTS: All 8 workers complained of dyspnea, while 4 of the 8 also complained of rash. On examination 3 workers were methacholine challenge positive and 2 had persistent rash. At follow-up 4 years later, 5 workers still had to use inhalation medication and one had progressive asthma and dermatitis. All 8 workers, by the time of the follow-up, had gone through economic and occupational changes. CONCLUSIONS: This case series reports on an unusual exposure to HDI. It is unusual in that: 1) There were two simultaneous sentinel cases with two different material safety data sheets (MSDS) for the same product, 2) Exposure was to volatile HDI and its decomposition products and 3) Hazardous conditions of exposure occurred at three different sites.
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3/46. Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi.

    Two forest workers affected with allergic contact dermatitis, which occurred only during work in forest areas, showed positive patch test reactions to lichens containing usnic acid and to isolated usnic acid. lichens are plants composed of fungi living in symbiosis with algae. Usnic acid, one of the lichenic acids which accumulates in lichenized fungi, is a monobasic acid with dibenzofuran structure and antibiotic properties. Dibenzofuran is chemically related to furocoumarans. lichens are plentiful in temperate zone forests and allergy to usnic acid represents some part of the "cedar-poisoning" problem in british columbia. Geographical distribution of lichens containing usnic acid suggests that allergy to usnic acid will be found to be more common than presently recognized.
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4/46. Occupational dermatitis from a one-component naphthalene type epoxy adhesive.

    In an electronics plant, a new one-component naphthalene type epoxy resin was used as an adhesive for reinforcing a circuit board. The resinous part of the adhesive consisted of diglycidyl ether of bisphenol A (DGEBA) and 1,6-bis(2,3-epoxypropoxy)naphthalene type epoxy resins. The hardener was methylhexahydrophthalic anhydride (MHHPA). Of 54 workers, 15 (27.8%) were diagnosed to have work-related dermatitis but were not patch tested. Therefore, it was impossible to determine the specific agent responsible for the worker's symptoms or to distinguish between allergic and irritant contact dermatitis. They worked without protective gloves until they started to develop skin symptoms. The hands were the commonly affected region (13 out of 15 cases). The latent period of dermatitis was very short (mean 2.2 weeks). Of these, 10 cases (66.7%) received medication for dermatitis, and 9 cases (60%) were transferred to other work. The work-related skin symptoms were closely related to the specific tasks, i.e., filling dispensers with the adhesive and manual application of the adhesive to a portion of a circuit board using a dispenser. For occupational hygiene reasons, contact with epoxy resins should be minimized by taking all possible measures into use, including protective gloves. Further studies are required to clarify the allergenicity of 1,6-bis(2,3-epoxypropoxy)naphthalene, since very little is known about the mechanism through which it leads to the symptoms of dermatitis.
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5/46. Pacemaker contact sensitivity: case report and review of the literature.

    Pacemaker contact sensitivity is a rare condition. Less than 25 reports of pacemaker skin reaction have been described over the past 30 years. This report describes one patient who developed contact dermatitis after implantation of two subsequent pacemakers. The diagnosis was made with skin patch tests that were positive to polyurethane 75D and polysulfone beige, two of the pacemaker and connector components. review of the literature and general guidelines for the management of this unusual condition is depicted in this report.
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6/46. Allergic "contact" dermatitis from disulfiram implants.

    Two cases of allergic "contact" dermatitis to implanted disulfiram (tetraethythiuramdisulfide or TETD) pellets are described. This side effect has never been reported before. Other local complications from disulfiram implantations are reviewed.
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7/46. Cross-reactivity with tagetes in arnica contact eczema.

    A 69-year-old patient, with known mercury and adhesive plaster allergy, developed facial dermatitis within 24 h of contact with arnica (arnica). skin testing showed positive reactions to arnica and, among various other plants of the Compositae, also to tagetes sp. hybr. (marigold). Cross-reactivity between tagetes and arnica has not previously been described.
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keywords = plant
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8/46. Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce).

    In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens.
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9/46. Allergic contact dermatitis in shiitake (Lentinus edodes (Berk) Sing) growers.

    A 42-year-old female shiitake grower was investigated to clarify the etiology of skin lesions which developed during the planting of shiitake hyphae into bed logs. She complained of repeated eczematous skin lesions during the planting season, from March to July, for 10 years. She handled 7,000 pieces of small conic blocks made of beech, with shiitake hyphae attached to their surface, per day, and 300,000 pieces altogether per season. She was positive on patch testing with extracts of shiitake hyphae. In contrast, female shiitake growers with skin lesions associated with work other than planting, and without skin lesions, were negative on patch testing to the hyphae. Moderate allergenicity was observed to extracts of shiitake hyphae in a guinea pig maximization test. These findings indicated the etiology of skin lesions in shiitake growers to be allergic contact dermatitis induced by shiitake hyphae.
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keywords = plant
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10/46. Occupational contact dermatitis due to croton (Codiaeum variegatum (L.) A. Juss var. pictum (Lodd.) Muell. Arg.). Sensitization by plants of the euphorbiaceae.

    One of today's most decorative and popular ornamental potted plants is croton. Handling this plant over a period of 6 months produced contact eczema of the hands in a nursery gardener. patch tests with croton leaves were positive. Control tests remained negative. Sensitization experiments in guinea pigs with a methanolic extract of the leaves were successful. All results of the study indicate that: -latex of croton produces no primary irritant reaction -latex is able to induce a real contact allergy -contact allergens are constituents of the milky sap. Whether the di- and triesters of phorbol so far isolated as irritant and cocarcinogenic factors from the latex of various euphorbiaceae species and sensitizers shall be investigated in further experiments.
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