1/49. Disseminated trichosporonosis with Trichosporon asahii.Trichosporon asahii fungemia was associated with multiple, purpuric, papular lesions on the abdomen and extremities in a 53-year-old man with acute myeloblastic leukemia. Histologically, budding yeasts were demonstrated in the dermis. The yeast-form fungus was identified as T. asahii.- - - - - - - - - - ranking = 1keywords = leukemia (Clic here for more details about this article) |
2/49. Cutaneous infection caused by Cylindrocarpon lichenicola in a patient with acute myelogenous leukemia.Cylindrocarpon lichenicola is a saprophytic soil fungus which has rarely been associated with human disease. We report the first case of localized invasive cutaneous infection caused by this fungus in a 53-year-old male from the rural midwestern united states with relapsed acute myelogenous leukemia. On admission for induction chemotherapy, the patient was noted to have an abrasive laceration between the fourth and fifth metacarpophalangeal joints and on the dorsum of the right hand, which progressed to frank ulceration following chemotherapy. A biopsy provided an initial diagnosis of an invasive fungal infection consistent with aspergillosis based on the histopathological appearance of the mold in tissue. Multiple positive fungal cultures which were obtained from the biopsied tissue were subsequently identified by microscopic and macroscopic characteristics to be C. lichenicola. The infection resolved following marrow regeneration, aggressive debridement of the affected tissue, and treatment with amphotericin b. This case extends the conditions associated with invasive disease caused by C. lichenicola.- - - - - - - - - - ranking = 7.5180526390252keywords = leukemia, myelogenous, myelogenous leukemia (Clic here for more details about this article) |
3/49. A case of disseminated cryptococcosis with skin eruption in a patient with acute leukemia.Disseminated cryptococcosis is a life-threatening infection caused by cryptococcus neoformans and cutaneous dissemination occurs in 10-15% of patients. We report a case of a 49-y-old leukemic patient with disseminated cryptococcosis who presented with fever, headache, normal cerebrospinal fluid profile and multiple skin lesions mimicking molluscum contagiosum.- - - - - - - - - - ranking = 4keywords = leukemia (Clic here for more details about this article) |
4/49. Invasive mycotic infections in the immunocompromised child.Oncologic therapy creates a highly vulnerable group of children with little or no natural immunity. In addition to the problems of coagulopathies, these children are prone to unusual infectious diseases. One group of saprophytic infections, the mycotic organisms, represents stubborn and often lethal diseases challenging present diagnostic and therapeutic skills. This is a case report of invasive Aspergillus organisms in the nose and premaxilla in a 9-year-old child suffering from acute monocytic leukemia.- - - - - - - - - - ranking = 1keywords = leukemia (Clic here for more details about this article) |
5/49. Disseminated candidiasis in a patient with acute myelogenous leukemia.Disseminated candidiasis is a frequently fatal condition that is rising steadily in immunocompromised patients. We present the case of a 62-year-old African American woman with acute myelogenous leukemia who developed characteristic cutaneous signs of systemic candidiasis. Early cultures and biopsies resulted in early diagnosis, which prompted proper antifungal therapy and a positive outcome.- - - - - - - - - - ranking = 7.5180526390252keywords = leukemia, myelogenous, myelogenous leukemia (Clic here for more details about this article) |
6/49. Successful outcome of disseminated fusarium infection with skin localization treated with voriconazole and amphotericin b-lipid complex in a patient with acute leukemia.A disseminated fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin b-lipid complex alone but responded successfully when voriconazole was added.- - - - - - - - - - ranking = 5keywords = leukemia (Clic here for more details about this article) |
7/49. Combination therapy of disseminated fusarium oxysporum infection with terbinafine and amphotericin b.A case of disseminated infection with fusarium oxysporum following chemotherapy of acute myelogenous leukemia is reported. Antifungal treatment was successful with a 13-day course of oral terbinafine 250 mg t.i.d. in combination with amphotericin b deoxycholate 1.0-1.5 mg/kg qd and subsequently intravenous liposomal amphotericin b 5 mg/kg qd. Preceding monotherapy with amphotericin b deoxycholate 1.0-1.5 mg/kg qd had not stopped the progression of infection. The combination therapy described here represents a novel approach to the treatment of fusarium spp. in the immunocompromised host in whom fusarium spp. are known to cause disseminated infection with high mortality.- - - - - - - - - - ranking = 1.503610527805keywords = leukemia, myelogenous, myelogenous leukemia (Clic here for more details about this article) |
8/49. ecthyma gangrenosum caused by disseminated Exserohilum in a child with leukemia: a case report and review of the literature.We report an 8-year-old boy with acute leukemia who developed ecthyma gangrenosum secondary to infection with Exserohilum spp., a rare cause of human disease. The skin, paranasal sinuses and lungs were involved. To the best of our knowledge, this is the first report of ecthyma gangrenosum caused by Exserohilum spp. This case emphasizes the importance of prompt skin biopsy for early diagnosis and treatment of this life-threatening infection.- - - - - - - - - - ranking = 5keywords = leukemia (Clic here for more details about this article) |
9/49. Voriconazole for the treatment of disseminated nodular cutaneous aspergillosis in a patient affected by acute myeloid leukemia.We report a 44-year-old patient with refractory acute myeloid leukemia who developed a rare form of disseminated cutaneous aspergillosis resulting from colonization in the deep reticular dermis of aspergillus flavus. Diagnosis was based on cutaneous biopsy. Antifungal therapy was started with liposomal amphotericin b (L AmB). However, the lesions continued to spread and there was a marked decline in the patient's clinical condition. Consequently, L AmB was replaced with voriconazole. Response to voriconazole was excellent with regression of the skin lesions and a rapid improvement of the patient's general clinical condition.- - - - - - - - - - ranking = 5keywords = leukemia (Clic here for more details about this article) |
10/49. Bull's-eye cutaneous infarct of zygomycosis: a bedside diagnosis confirmed by touch preparation.We report an immunocompromised woman with chronic lymphocytic leukemia who developed cutaneous zygomycosis at the site of an arterial line. The initial lesion resembled a bulls-eye. Bull's-eye lesions of zygomycosis have been reported twice before. Recognition of this sign may allow the dermatologist to make a rapid presumptive diagnosis and initiate treatment for this life-threatening infection.- - - - - - - - - - ranking = 1keywords = leukemia (Clic here for more details about this article) |
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